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TAX1BP1 and TBC1D17
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
TAX1BP1
TBC1D17
Gene Name
Tax1 (human T-cell leukemia virus type I) binding protein 1
TBC1 domain family, member 17
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Extracellular Vesicular Exosome
Autophagic Vacuole
Cytosol
Cytoplasmic Vesicle
Molecular Function
Protein Binding
Kinase Binding
Rab GTPase Activator Activity
Protein Binding
Biological Process
Apoptotic Process
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Type I Interferon Production
Negative Regulation Of Apoptotic Process
Innate Immune Response
Autophagy
Protein Transport
Positive Regulation Of Rab GTPase Activity
Retrograde Transport, Endosome To Golgi
Regulation Of Cilium Assembly
Pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Negative regulators of RIG-I/MDA5 signaling
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
40 interactors:
ARHGAP1
CALCOCO2
CNTN2
COG7
CWF19L2
CXXC1
DAZAP2
DSTN
EMILIN1
FAM168A
FAM189A2
FOXC2
GABARAP
IKBKG
KIF5B
LGALS8
LMO3
MAP1LC3B
MAP1LC3C
MRPL11
MRPL53
MYO6
NMRK1
ORC5
PLEKHN1
RAB18
RAD18
RIPK1
RNF11
SSX2
STARD13
TBC1D17
TCEA2
TNFAIP3
TNIP1
TNIP3
TRAF6
TSG101
TSHZ3
UBC
19 interactors:
ASCC2
CALCOCO1
CCT5
CDKN2D
DHX29
FBL
GABARAPL1
GPS1
GTF3C1
MAP1LC3A
MAP1LC3B
NIPSNAP1
OPTN
RAB1A
RAB5A
RAB5B
RAB5C
SLC1A5
TAX1BP1
Entrez ID
8887
79735
HPRD ID
05618
15471
Ensembl ID
ENSG00000106052
ENSG00000104946
Uniprot IDs
A4D196
B4DSG5
Q86VP1
Q9HA65
PDB IDs
Enriched GO Terms of Interacting Partners
?
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Toll-like Receptor Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
MyD88-independent Toll-like Receptor Signaling Pathway
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Regulation Of Innate Immune Response
Toll-like Receptor 4 Signaling Pathway
Organelle Disassembly
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
TRIF-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Nucleophagy
Immune Response-regulating Signaling Pathway
JNK Cascade
Cellular Response To Stress
Mitochondrion Degradation
Regulation Of Vascular Wound Healing
Regulation Of Type I Interferon Production
Stress-activated MAPK Cascade
Negative Regulation Of Intracellular Signal Transduction
Stress-activated Protein Kinase Signaling Cascade
Regulation Of Intracellular Signal Transduction
Positive Regulation Of NF-kappaB Transcription Factor Activity
Autophagic Vacuole Assembly
Positive Regulation Of Immune Response
Positive Regulation Of Immune System Process
Activation Of MAPK Activity
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Macroautophagy
Regulation Of Signaling
I-kappaB Kinase/NF-kappaB Signaling
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Autophagy
Toll-like Receptor 9 Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Viral Protein Processing
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Intracellular Receptor Signaling Pathway
Positive Regulation Of Type I Interferon Production
Membrane Organization
Macroautophagy
Autophagic Vacuole Assembly
Cellular Response To Starvation
Rab Protein Signal Transduction
Autophagy
Cellular Response To Nutrient Levels
Response To Starvation
Cellular Response To Extracellular Stimulus
Nucleophagy
Response To Nutrient Levels
Response To Extracellular Stimulus
Vacuole Organization
Mitochondrion Degradation
Organelle Disassembly
Plasma Membrane To Endosome Transport
Ras Protein Signal Transduction
Response To External Stimulus
Cellular Response To Nitrogen Starvation
Cellular Response To Stress
Membrane Fusion
Cytoplasmic Transport
Regulation Of Endocytosis
Membrane Organization
Organelle Assembly
Response To Stimulus
Endosomal Transport
Intracellular Protein Transport
Response To Stress
Histone Glutamine Methylation
Extracellular Amino Acid Transport
Small GTPase Mediated Signal Transduction
Interleukin-8 Secretion
Cargo Loading Into COPII-coated Vesicle
Peptidyl-glutamine Methylation
Golgi Organization
Response To Other Organism
Receptor Internalization Involved In Canonical Wnt Signaling Pathway
Regulation Of Endosome Size
Response To Biotic Stimulus
Regulation Of Vesicle-mediated Transport
Interleukin-8 Production
SnoRNA Metabolic Process
Negative Regulation Of Receptor Recycling
Cellular Protein Localization
Mitochondrion Organization
Protein Transport
Negative Regulation Of Intracellular Signal Transduction
Vesicle-mediated Transport
Endomembrane System Organization
5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter
Tagcloud
?
100nm
48h
81m
anapc13
calm2
carcinogenic
diarrheic
drawing
exhaustive
explanation
hn1
malat1
mapre2
mllt11
molluscs
oa
okadaic
pathologies
poisoning
positives
pttg1
rodents
sga
shellfish
shsy5y
ssh
subtractive
toxins
tumourigenesis
Tagcloud (Difference)
?
100nm
48h
81m
anapc13
calm2
carcinogenic
diarrheic
drawing
exhaustive
explanation
hn1
malat1
mapre2
mllt11
molluscs
oa
okadaic
pathologies
poisoning
positives
pttg1
rodents
sga
shellfish
shsy5y
ssh
subtractive
toxins
tumourigenesis
Tagcloud (Intersection)
?