TAX1BP1 and RAD54L2

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		TAX1BP1	RAD54L2
Description		Tax1 binding protein 1	RAD54 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Cytoplasm Mitochondrion Autophagosome Cytosol Cytoplasmic Vesicle Extracellular Exosome	Nucleus Nuclear Body
	Molecular Function	Protein Binding Zinc Ion Binding Kinase Binding Protein-macromolecule Adaptor Activity Signaling Adaptor Activity Metal Ion Binding	Nucleotide Binding DNA Binding Transcription Coregulator Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity ATP-dependent Chromatin Remodeler Activity
	Biological Process	Immune System Process Cytoplasmic Pattern Recognition Receptor Signaling Pathway Autophagy Apoptotic Process Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Protein K48-linked Ubiquitination Protein Localization To Phagocytic Vesicle Negative Regulation Of Interleukin-1-mediated Signaling Pathway	Chromatin Organization Chromatin Remodeling Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)	Estimated glomerular filtration rate ( 31152163)
Interacting Genes		72 interacting genes: ARHGAP1 ARK2N AZI2 CBX8 COG7 CWF19L2 CXXC1 DAXX DAZAP2 DSTN ENTREP1 FAM161A FAM168A FAM90A1 FOXC2 GABARAP GABARAPL1 GABARAPL2 IGFN1 IKBKG KANK2 KAT5 KIF5B L3MBTL2 LITAF LMO3 LNX1 LRATD2 MAP1LC3C MRPL11 MRPL53 MYO6 NMRK1 NTAQ1 ORC5 PIBF1 PLEKHB2 PLEKHN1 POLR1C RAB18 RAD18 RAD23B RAD54L2 RIPK1 RNF11 RNF26 SCNM1 SH3GLB1 SSX2 STARD13 TBC1D15 TBC1D17 TCAF1 TCEA2 TCL1A TNFAIP3 TNIP3 TRAF4 TRAF6 TRAPPC6A TRIM14 TRIM45 TSEN2 TSG101 TSHZ3 UBA52 UBASH3A UBB UBC UBTFL1 USP2 ZNF446	44 interacting genes: AR ATN1 ATXN1 ATXN1L BANP BHLHE40 CBX3 CRK FAM118B FXR2 HMG20A HNRNPCL1 HOMER1 IMPDH1 KIFC3 KRTAP6-3 LCE1D LCE1F NR3C1 NR5A1 NR5A2 PAICS PIAS1 POU1F1 PPARG PSMA3 RAD51 RBPMS RUNX1T1 RXRA SIAH1 SQSTM1 SUMO1 SUMO2 SUMO3 TAX1BP1 TFAP2D THAP1 TRAF2 TRAF4 UBE2I VCX ZBTB26 ZC2HC1A
Entrez ID		8887	23132
HPRD ID		05618	10018
Ensembl ID		ENSG00000106052	ENSG00000164080
Uniprot IDs		B4DSG5 Q86VP1	B3KV54 Q9Y4B4
PDB IDs		2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G 8W6A 8W6B
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Binding Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Protein Binding Autophagosome Autophagosome Maturation Protein-containing Complex Disassembly Autophagosome Membrane Cytoplasm Modification-dependent Protein Catabolic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Polyubiquitin Modification-dependent Protein Binding Macromolecule Catabolic Process Endosome Membrane Proteolysis Involved In Protein Catabolic Process Protein Tag Activity Autophagy GABA Receptor Binding Autophagosome Assembly Regulation Of Canonical NF-kappaB Signal Transduction Macroautophagy Autophagosome Organization Mitophagy Ubiquitin Protein Ligase Activity Cellular Response To Starvation WW Domain Binding Post-translational Protein Modification Protein Ubiquitination Autophagy Of Mitochondrion Catabolic Process Regulation Of Protein Modification Process Signaling Adaptor Activity Response To Starvation Protein Modification Process Proteolysis Ubiquitin-dependent Protein Catabolic Process Regulation Of Macromolecule Metabolic Process Protein Modification By Small Protein Conjugation Beta-tubulin Binding Regulation Of Primary Metabolic Process Cellular Response To Nutrient Levels Organelle Assembly Vacuole Organization Identical Protein Binding Zinc Ion Binding Cytosol Positive Regulation Of Protein Modification Process	Identical Protein Binding Enzyme Binding PML Body Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Transcription Coregulator Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Receptor Activity Nucleus Postsynaptic Cytosol Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nucleobase-containing Compound Biosynthetic Process Protein Sumoylation Nucleoplasm Negative Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase II 'de Novo' XMP Biosynthetic Process Presynaptic Cytosol Ubiquitin Protein Ligase Binding Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Intracellular Receptor Signaling Pathway Signaling Adaptor Activity Hormone-mediated Signaling Pathway Chromatin Regulation Of Primary Metabolic Process Chromatin Binding GMP Biosynthetic Process IMP Dehydrogenase Activity DNA-binding Transcription Factor Activity Negative Regulation Of Metabolic Process Protein Tag Activity Purine Ribonucleoside Monophosphate Biosynthetic Process Zinc Ion Binding Regulation Of Gene Expression SUMO Transferase Activity Sequence-specific DNA Binding Double-stranded DNA Binding RNA Polymerase II Transcription Regulator Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process
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