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TAX1BP1 and FAM189A2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
TAX1BP1
FAM189A2
Gene Name
Tax1 (human T-cell leukemia virus type I) binding protein 1
family with sequence similarity 189, member A2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Extracellular Vesicular Exosome
Cellular_component
Integral Component Of Membrane
Molecular Function
Protein Binding
Kinase Binding
Molecular_function
Biological Process
Apoptotic Process
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Type I Interferon Production
Negative Regulation Of Apoptotic Process
Innate Immune Response
Biological_process
Pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Negative regulators of RIG-I/MDA5 signaling
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
40 interactors:
ARHGAP1
CALCOCO2
CNTN2
COG7
CWF19L2
CXXC1
DAZAP2
DSTN
EMILIN1
FAM168A
FAM189A2
FOXC2
GABARAP
IKBKG
KIF5B
LGALS8
LMO3
MAP1LC3B
MAP1LC3C
MRPL11
MRPL53
MYO6
NMRK1
ORC5
PLEKHN1
RAB18
RAD18
RIPK1
RNF11
SSX2
STARD13
TBC1D17
TCEA2
TNFAIP3
TNIP1
TNIP3
TRAF6
TSG101
TSHZ3
UBC
9 interactors:
BAG3
CALCOCO2
SFN
STAM2
TAX1BP1
UBQLN1
UBXN1
WWP1
WWP2
Entrez ID
8887
9413
HPRD ID
05618
16255
Ensembl ID
ENSG00000106052
ENSG00000135063
Uniprot IDs
A4D196
B4DSG5
Q86VP1
Q15884
Q8WU02
PDB IDs
Enriched GO Terms of Interacting Partners
?
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Toll-like Receptor Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
MyD88-independent Toll-like Receptor Signaling Pathway
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Regulation Of Innate Immune Response
Toll-like Receptor 4 Signaling Pathway
Organelle Disassembly
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
TRIF-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Nucleophagy
Immune Response-regulating Signaling Pathway
JNK Cascade
Cellular Response To Stress
Mitochondrion Degradation
Regulation Of Vascular Wound Healing
Regulation Of Type I Interferon Production
Stress-activated MAPK Cascade
Negative Regulation Of Intracellular Signal Transduction
Stress-activated Protein Kinase Signaling Cascade
Regulation Of Intracellular Signal Transduction
Positive Regulation Of NF-kappaB Transcription Factor Activity
Autophagic Vacuole Assembly
Positive Regulation Of Immune Response
Positive Regulation Of Immune System Process
Activation Of MAPK Activity
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Macroautophagy
Regulation Of Signaling
I-kappaB Kinase/NF-kappaB Signaling
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Autophagy
Toll-like Receptor 9 Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Viral Protein Processing
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Intracellular Receptor Signaling Pathway
Positive Regulation Of Type I Interferon Production
Membrane Organization
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Viral Entry Into Host Cell
Entry Into Host Cell
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Interaction With Host
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Viral Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Regulation Of Epidermal Cell Division
Protein Catabolic Process
Regulation Of Apoptotic Process
Regulation Of Cell Death
Viral Life Cycle
Regulation Of Protein Ubiquitination
Cellular Macromolecule Catabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Keratinocyte Development
Negative Regulation Of Keratinocyte Proliferation
Apoptotic Process
Negative Regulation Of Cell Death
Negative Regulation Of Cellular Metabolic Process
Programmed Cell Death
Positive Regulation Of Protein Export From Nucleus
Regulation Of Metabolic Process
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Cell Death
Death
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Establishment Of Skin Barrier
Apoptotic Signaling Pathway
Negative Regulation Of Proteolysis
Regulation Of Water Loss Via Skin
Negative Regulation Of Protein Processing
Positive Regulation Of Epidermal Cell Differentiation
Regulation Of Keratinocyte Proliferation
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Protein Processing
Response To Stimulus
Regulation Of Potassium Ion Transmembrane Transporter Activity
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Protein K63-linked Ubiquitination
Regulation Of Protein Export From Nucleus
Release Of Cytochrome C From Mitochondria
Tagcloud
?
100nm
48h
81m
anapc13
calm2
carcinogenic
diarrheic
drawing
exhaustive
explanation
hn1
malat1
mapre2
mllt11
molluscs
oa
okadaic
pathologies
poisoning
positives
pttg1
rodents
sga
shellfish
shsy5y
ssh
subtractive
toxins
tumourigenesis
Tagcloud (Difference)
?
100nm
48h
81m
anapc13
calm2
carcinogenic
diarrheic
drawing
exhaustive
explanation
hn1
malat1
mapre2
mllt11
molluscs
oa
okadaic
pathologies
poisoning
positives
pttg1
rodents
sga
shellfish
shsy5y
ssh
subtractive
toxins
tumourigenesis
Tagcloud (Intersection)
?