TAX1BP1 and ENTREP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TAX1BP1	ENTREP1
Description		Tax1 binding protein 1	endosomal transmembrane epsin interactor 1
Image			No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Cytoplasm Mitochondrion Autophagosome Cytosol Cytoplasmic Vesicle Extracellular Exosome	Endosome Plasma Membrane Membrane Early Endosome Membrane Late Endosome Membrane Recycling Endosome Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Kinase Binding Protein-macromolecule Adaptor Activity Signaling Adaptor Activity Metal Ion Binding	Protein Binding Ubiquitin Ligase Activator Activity
	Biological Process	Immune System Process Cytoplasmic Pattern Recognition Receptor Signaling Pathway Autophagy Apoptotic Process Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Protein K48-linked Ubiquitination Protein Localization To Phagocytic Vesicle Negative Regulation Of Interleukin-1-mediated Signaling Pathway	Negative Adaptation Of Signaling Pathway Receptor Internalization CXCL12-activated CXCR4 Signaling Pathway
Pathways		Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)
Interacting Genes		72 interacting genes: ARHGAP1 ARK2N AZI2 CBX8 COG7 CWF19L2 CXXC1 DAXX DAZAP2 DSTN ENTREP1 FAM161A FAM168A FAM90A1 FOXC2 GABARAP GABARAPL1 GABARAPL2 IGFN1 IKBKG KANK2 KAT5 KIF5B L3MBTL2 LITAF LMO3 LNX1 LRATD2 MAP1LC3C MRPL11 MRPL53 MYO6 NMRK1 NTAQ1 ORC5 PIBF1 PLEKHB2 PLEKHN1 POLR1C RAB18 RAD18 RAD23B RAD54L2 RIPK1 RNF11 RNF26 SCNM1 SH3GLB1 SSX2 STARD13 TBC1D15 TBC1D17 TCAF1 TCEA2 TCL1A TNFAIP3 TNIP3 TRAF4 TRAF6 TRAPPC6A TRIM14 TRIM45 TSEN2 TSG101 TSHZ3 UBA52 UBASH3A UBB UBC UBTFL1 USP2 ZNF446	11 interacting genes: BAG3 CALCOCO2 NEDD4 OPTN SFN STAM2 TAX1BP1 UBQLN1 UBXN1 WWP1 WWP2
Entrez ID		8887	9413
HPRD ID		05618	16255
Ensembl ID		ENSG00000106052	ENSG00000135063
Uniprot IDs		B4DSG5 Q86VP1	Q15884 Q8WU02
PDB IDs		2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G 8W6A 8W6B
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Binding Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Protein Binding Autophagosome Autophagosome Maturation Protein-containing Complex Disassembly Autophagosome Membrane Cytoplasm Modification-dependent Protein Catabolic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Polyubiquitin Modification-dependent Protein Binding Macromolecule Catabolic Process Endosome Membrane Proteolysis Involved In Protein Catabolic Process Protein Tag Activity Autophagy GABA Receptor Binding Autophagosome Assembly Regulation Of Canonical NF-kappaB Signal Transduction Macroautophagy Autophagosome Organization Mitophagy Ubiquitin Protein Ligase Activity Cellular Response To Starvation WW Domain Binding Post-translational Protein Modification Protein Ubiquitination Autophagy Of Mitochondrion Catabolic Process Regulation Of Protein Modification Process Signaling Adaptor Activity Response To Starvation Protein Modification Process Proteolysis Ubiquitin-dependent Protein Catabolic Process Regulation Of Macromolecule Metabolic Process Protein Modification By Small Protein Conjugation Beta-tubulin Binding Regulation Of Primary Metabolic Process Cellular Response To Nutrient Levels Organelle Assembly Vacuole Organization Identical Protein Binding Zinc Ion Binding Cytosol Positive Regulation Of Protein Modification Process	Catabolic Process Autophagy Regulation Of Macroautophagy Autophagosome Polyubiquitin Modification-dependent Protein Binding Regulation Of Autophagy Macroautophagy Cytosol Phosphoserine Residue Binding Negative Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Cation Transmembrane Transport Macromolecule Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Potassium Channel Inhibitor Activity Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Monoatomic Ion Transmembrane Transport Protein Catabolic Process Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Macroautophagy Negative Regulation Of Monoatomic Ion Transport Ubiquitin Binding Proteolysis Involved In Protein Catabolic Process Ubiquitin Ligase Complex Negative Regulation Of Transmembrane Transport Regulation Of Nucleocytoplasmic Transport Cytoplasm Cellular Response To Unfolded Protein Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Intracellular Transport Negative Regulation Of Potassium Ion Transmembrane Transport Regulation Of ERAD Pathway Negative Regulation Of Transporter Activity Cellular Response To Topologically Incorrect Protein Negative Regulation Of Potassium Ion Transport Positive Regulation Of Autophagy Proteasomal Protein Catabolic Process Aggresome Regulation Of Protein Export From Nucleus Intracellular Protein Transport Protein-macromolecule Adaptor Activity Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Protein Transport Intracellular Protein Localization Protein Ubiquitination Ubiquitin-protein Transferase Activity Protein Localization To Organelle Proteolysis Regulation Of Monoatomic Cation Transmembrane Transport
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