TAX1BP1 and CXXC1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TAX1BP1	CXXC1
Gene Name		Tax1 (human T-cell leukemia virus type I) binding protein 1	CXXC finger protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck Histone Methyltransferase Complex Set1C/COMPASS Complex
	Molecular Function	Protein Binding Kinase Binding	Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K4 Specific) Unmethylated CpG Binding
	Biological Process	Apoptotic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process Innate Immune Response	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process Positive Regulation Of Transcription, DNA-templated Histone H3-K4 Methylation
Pathways		RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Negative regulators of RIG-I/MDA5 signaling Innate Immune System	IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS			Chronic lymphocytic leukemia ( 20062064)
Protein-Protein Interactions		40 interactors: ARHGAP1 CALCOCO2 CNTN2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN EMILIN1 FAM168A FAM189A2 FOXC2 GABARAP IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 MYO6 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP1 TNIP3 TRAF6 TSG101 TSHZ3 UBC	8 interactors: EP300 MEOX2 NR5A1 PPP1CA SMURF1 TAX1BP1 TBP TP53
Entrez ID		8887	30827
HPRD ID		05618	10852
Ensembl ID		ENSG00000106052	ENSG00000154832
Uniprot IDs		A4D196 B4DSG5 Q86VP1	Q9P0U4
PDB IDs			3QMB 3QMC 3QMD 3QMG 3QMH 3QMI
Enriched GO Terms of Interacting Partners?		Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling MyD88-independent Toll-like Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Organelle Disassembly Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Nucleophagy Immune Response-regulating Signaling Pathway JNK Cascade Cellular Response To Stress Mitochondrion Degradation Regulation Of Vascular Wound Healing Regulation Of Type I Interferon Production Stress-activated MAPK Cascade Negative Regulation Of Intracellular Signal Transduction Stress-activated Protein Kinase Signaling Cascade Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Autophagic Vacuole Assembly Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Activation Of MAPK Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Macroautophagy Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Autophagy Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Protein Processing Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intracellular Receptor Signaling Pathway Positive Regulation Of Type I Interferon Production Membrane Organization	Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Rhythmic Process Somitogenesis Somite Development Regulation Of Gene Expression Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Segmentation Transforming Growth Factor Beta Receptor Signaling Pathway Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Transcription, DNA-templated Response To Transforming Growth Factor Beta Photoperiodism Entrainment Of Circadian Clock Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Anterior/posterior Pattern Specification Positive Regulation Of Cellular Biosynthetic Process Multicellular Organismal Aging Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Deacetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Neuron Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Death Death Epithelium Development Histone H2B Acetylation Transcription, DNA-templated Pattern Specification Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage RNA Biosynthetic Process Regulation Of Circadian Rhythm Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels
Tagcloud ?		100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis	accessibility cfp cfp1 cg cpg cpgs dense dinucleotides elegans genomes h3k4me3 hot invertebrates irrelevant islands lie nonmethylated occupied ortholog promoters recruits remainder set1 setd1a sparsely unmethylated unusually vertebrate
Tagcloud (Difference) ?		100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis	accessibility cfp cfp1 cg cpg cpgs dense dinucleotides elegans genomes h3k4me3 hot invertebrates irrelevant islands lie nonmethylated occupied ortholog promoters recruits remainder set1 setd1a sparsely unmethylated unusually vertebrate
Tagcloud (Intersection) ?