HDAC8 and MDC1

  • Number of citations of the paper that reports this interaction (PMID 14578343)
  • 66
  • Data Source:
  • BioGRID (unspecified method)

HDAC8

MDC1

Gene Name histone deacetylase 8 mediator of DNA-damage checkpoint 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 9 interactors: ESRRA HIST1H3A HIST1H4A HIST3H3 HIST4H4 MDC1 PRKACA RTN1 RUNX1T1 37 interactors: ANAPC1 ATM BARD1 BRCA1 CASP3 CENPC CHEK2 COPS5 CREBBP CSNK2A1 DTX2 EP300 GATA4 H2AFX HDAC10 HDAC8 HINFP LOC729324 NBN NCL PIAS1 PIAS4 PRIM1 RAD50 RAD51 RNF8 SMC1A SUMO1 SUMO2 TP53 TP53BP1 UIMC1 USP28 VAMP5 WHSC1 WRN ZNF251
Entrez ID 55869 9656
HPRD ID 02227 16252
Ensembl ID ENSG00000147099 ENSG00000137337
Uniprot IDs Q9BY41 A1Z5I9 Q14676
PDB IDs 1T64 1T67 1T69 1VKG 1W22 2V5W 2V5X 3EW8 3EWF 3EZP 3EZT 3F06 3F07 3F0R 3MZ3 3MZ4 3MZ6 3MZ7 3RQD 3SFF 3SFH 2ADO 2AZM 2ETX 3K05 3UEO 3UMZ 3UN0 3UNM 3UNN 3UOT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activator  acylthiourea  anticancer  calorimetric  conformed  cooperative  deacetylase  derivative  detailed  discriminatory  encoded  feature  insight  isothermal  isozyme  kinetic  kinetics  malignancy  mechanistic  modeling  neuroblastoma  served  sh  steady  sy5y  thermodynamics  titration  tm  wherein 
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
Tagcloud (Difference) ?
activator  acylthiourea  anticancer  calorimetric  conformed  cooperative  deacetylase  derivative  detailed  discriminatory  encoded  feature  insight  isothermal  isozyme  kinetic  kinetics  malignancy  mechanistic  modeling  neuroblastoma  served  sh  steady  sy5y  thermodynamics  titration  tm  wherein 
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
Tagcloud (Intersection) ?