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GSTM4 and NELFCD
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
GSTM4
NELFCD
Gene Name
glutathione S-transferase mu 4
negative elongation factor complex member C/D
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Nucleoplasm
Membrane
NELF Complex
Molecular Function
Glutathione Transferase Activity
Enzyme Binding
Protein Homodimerization Activity
Glutathione Binding
Protein Binding
Biological Process
Glutathione Metabolic Process
Xenobiotic Metabolic Process
Nitrobenzene Metabolic Process
Xenobiotic Catabolic Process
Small Molecule Metabolic Process
Glutathione Derivative Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Gene Expression
Viral Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Viral Transcription
Pathways
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
Defective UGT1A4 causes hyperbilirubinemia
Glutathione conjugation
Metabolic disorders of biological oxidation enzymes
Phase II conjugation
Defective UGT1A1 causes hyperbilirubinemia
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
Biological oxidations
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
Defective GGT1 causes Glutathionuria (GLUTH)
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
RNA Polymerase II Pre-transcription Events
Late Phase of HIV Life Cycle
Pausing and recovery of Tat-mediated HIV elongation
Formation of RNA Pol II elongation complex
HIV elongation arrest and recovery
HIV Life Cycle
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
HIV Transcription Elongation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Glutathione
Glutathione Sulfonic Acid
S-Octylglutathione
Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine
1-Hydroxy-2-S-Glutathionyl-3-Para-Nitrophenoxy-Propane
S-Hexylglutathione
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
APLP1
GSTM3
IGSF21
LRIF1
MED31
NELFCD
TLE1
TP53
UNC119
ZBTB16
19 interactors:
AAMP
AR
ARAF
ARPC4
CACNA1A
DNAJA1
ENDOV
EPRS
FRMD5
GSTM4
HDAC11
MTA1
NELFA
PRMT5
SERF2
SMAD4
TXK
UBE3A
ZNF638
Entrez ID
2948
51497
HPRD ID
00706
16096
Ensembl ID
ENSG00000168765
ENSG00000101158
Uniprot IDs
Q03013
H0UI80
Q8IXH7
PDB IDs
4GTU
Enriched GO Terms of Interacting Partners
?
Transcription From RNA Polymerase II Promoter
Cellular Aromatic Compound Metabolic Process
RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Negative Regulation Of Fibroblast Proliferation
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Clathrin-mediated Endocytosis
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Fibroblast Proliferation
Regulation Of Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Macromitophagy
Negative Regulation Of Caveolin-mediated Endocytosis
Oligodendrocyte Apoptotic Process
Negative Regulation Of Gene Expression
Cellular Detoxification Of Nitrogen Compound
Cytokinesis, Completion Of Separation
Negative Regulation Of Helicase Activity
Cellular Response To Norepinephrine Stimulus
Notch Signaling Pathway
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Nitrobenzene Metabolic Process
Negative Regulation Of Cell Proliferation
Positive Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Protein Localization To Nucleus
Positive Regulation Of NK T Cell Differentiation
Detoxification Of Nitrogen Compound
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Response To Toxic Substance
Regulation Of RNA Metabolic Process
Positive Regulation Of Thymocyte Apoptotic Process
Response To Norepinephrine
Positive Regulation Of Cell Aging
Establishment Of Blood-nerve Barrier
Male Germ-line Stem Cell Asymmetric Division
Androgen Receptor Signaling Pathway
Endothelial Cell Activation
Intracellular Steroid Hormone Receptor Signaling Pathway
Negative Regulation Of Biosynthetic Process
RNA Metabolic Process
Transcription, DNA-templated
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Intracellular Receptor Signaling Pathway
Growth
Regulation Of Protein Ubiquitination
Gene Expression
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Cell Death
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Integrin Biosynthetic Process
Cerebellar Molecular Layer Development
Sperm Entry
Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis
Regulation Of Metabolic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stimulus
Cellular Metabolic Process
Prostate Gland Development
Heterocycle Metabolic Process
Biosynthetic Process
Prolyl-tRNA Aminoacylation
Vestibular Nucleus Development
Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine
Nephrogenic Mesenchyme Morphogenesis
Positive Regulation Of Protein Autoubiquitination
Regulation Of Establishment Of Protein Localization
Rhythmic Process
Circadian Regulation Of Gene Expression
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Glutamyl-tRNA Aminoacylation
Positive Regulation Of Integrin Biosynthetic Process
Cerebellum Maturation
Nephrogenic Mesenchyme Development
Metanephric Mesenchyme Morphogenesis
Musculoskeletal Movement, Spinal Reflex Action
Regulation Of Protein Autoubiquitination
NK T Cell Differentiation
Positive Regulation Of Cellular Metabolic Process
Cellular Component Assembly
Tagcloud
?
abundances
agt
ahr
amongst
aryl
came
car3
coherency
constitutive
contrasting
creg1
ctsc
e2f6
enpp1
gatm
halogenated
hydrocarbon
hydrocarbons
inferences
kcnj8
me1
overlap
pdk1
physiologic
profiled
slc35a3
sqrdl
transcriptomic
xenobiotic
Tagcloud (Difference)
?
abundances
agt
ahr
amongst
aryl
came
car3
coherency
constitutive
contrasting
creg1
ctsc
e2f6
enpp1
gatm
halogenated
hydrocarbon
hydrocarbons
inferences
kcnj8
me1
overlap
pdk1
physiologic
profiled
slc35a3
sqrdl
transcriptomic
xenobiotic
Tagcloud (Intersection)
?