GSTM4

Description		glutathione S-transferase mu 4
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Protein Binding Transferase Activity Lyase Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Glutathione Binding
	Biological Process	Lipid Metabolic Process Glutathione Metabolic Process Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Long-chain Fatty Acid Biosynthetic Process
Pathways		Glutathione conjugation Biosynthesis of maresin conjugates in tissue regeneration (MCTR)
Drugs		Glutathione Glutathione sulfonic acid S-octylglutathione Glutathione disulfide gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine Deoxycholic acid 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane S-Hexylglutathione
Diseases
GWAS		Alcohol dependence ( 33290381) Seasonality and depression ( 30217971)
Interacting Genes		10 interacting genes: APLP1 GSTM3 IGSF21 LRIF1 MED31 NELFCD TLE1 TP53 UNC119 ZBTB16
Entrez ID		2948
HPRD ID		00706
Ensembl ID		ENSG00000168765
Uniprot IDs		A0A140VKE3 A6NNT0 Q03013
PDB IDs		4GTU
Enriched GO Terms of Interacting Partners?		Cellular Response To Norepinephrine Stimulus Alpha-2B Adrenergic Receptor Binding Regulation Of Primary Metabolic Process Cytosolic MRNA Polyadenylation Alpha-2C Adrenergic Receptor Binding Response To Norepinephrine System Development Central Nervous System Development Identical Protein Binding Developmental Process Nitrobenzene Metabolic Process Detoxification Of Nitrogen Compound Cellular Detoxification Of Nitrogen Compound Establishment Of Blood-nerve Barrier Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Pentose-phosphate Shunt Positive Regulation Of Thymocyte Apoptotic Process Response To Actinomycin D T Cell Proliferation Involved In Immune Response Negative Regulation Of Helicase Activity Transcription Repressor Complex Oxidative Stress-induced Premature Senescence Positive Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of G1 To G0 Transition PML Body Glucose Catabolic Process To Lactate Via Pyruvate Positive Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Fibroblast Proliferation Germ Cell Nucleus Cellular Response To Actinomycin D Negative Regulation Of Fibroblast Proliferation Regulation Of Transcription Initiation By RNA Polymerase II Germ-line Stem Cell Division Positive Regulation Of NK T Cell Differentiation Type 2 Angiotensin Receptor Binding Male Germ-line Stem Cell Asymmetric Division Negative Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation NELF Complex Regulation Of Macromolecule Metabolic Process Nuclear Matrix Alpha-2A Adrenergic Receptor Binding Histone Deacetylase Regulator Activity Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly
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