CNDP2 and NDRG1

Number of citations of the paper that reports this interaction (PubMedID 17220478)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		CNDP2	NDRG1
Description		carnosine dipeptidase 2	N-myc downstream regulated 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Extracellular Exosome	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Microtubule Plasma Membrane Adherens Junction Microtubule Cytoskeleton Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Carboxypeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Dipeptidase Activity Metal Ion Binding Metallodipeptidase Activity	Protein Binding Microtubule Binding Nickel Cation Binding Small GTPase Binding Gamma-tubulin Binding Cadherin Binding
	Biological Process	Proteolysis	Signal Transduction Negative Regulation Of Cell Population Proliferation Response To Metal Ion DNA Damage Response, Signal Transduction By P53 Class Mediator Peripheral Nervous System Myelin Maintenance Mast Cell Activation Cellular Response To Hypoxia
Pathways		Glutathione synthesis and recycling Paracetamol ADME	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Refractive error ( 23396134 32231278) Serum metabolite levels ( 33031748)	Estimated glomerular filtration rate ( 31015462) Left-handedness ( 32989287) Nontyphoidal Salmonella bacteraemia ( 29523850) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)
Interacting Genes		8 interacting genes: CNDP1 CRK DAPP1 FILNC1 NDRG1 OGT STAT3 ZDHHC17	71 interacting genes: ACSL3 ACTG1 AP1M2 AP2M1 APOA1 APOA2 ARL4D ATP1A1 CANX CDH1 CLTC CNDP2 COPB2 CTNNB1 DDX1 DDX5 DLST EEF1G EEF2 EIF2S3 EIF3E ETS2 EWSR1 FASN GSK3B HNRNPF HNRNPH1 HNRNPU HSD17B4 HSP90AA1 HSPA5 ILF3 KIF5B LDHA MAOA MLH1 MME MYC NCL NR4A1 PABPC1 PHYHIP PKM PPP2R2A PRKACA PSMC2 PSMC3 PSMD2 RPL24 RPL3 RPL4 RPN2 RPS16 RPS20 RPS26 RPS3 RPS6 RPS8 RTN1 RUVBL2 S100B SEC23A SGK1 SHMT2 TAF9 TARS1 TLE3 UPF1 VCP XRCC5 ZNF155
Entrez ID		55748	10397
HPRD ID		09893	05586
Ensembl ID		ENSG00000133313	ENSG00000104419
Uniprot IDs		Q96KP4	Q8N959 Q92597
PDB IDs		4RUH	6ZMM
Enriched GO Terms of Interacting Partners?		Regulation Of Natural Killer Cell Mediated Immunity Helper T Cell Diapedesis Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication Signaling Receptor Binding Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Response To Peptide Hormone Signaling Adaptor Activity Protein Phosphorylated Amino Acid Binding Regulation Of Rac Protein Signal Transduction Positive Regulation Of Signaling Regulation Of Natural Killer Cell Mediated Cytotoxicity Response To Cholecystokinin Regulation Of ATP Metabolic Process Regulation Of Carbohydrate Catabolic Process Chromatin DNA Binding Regulation Of Glycolytic Process Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Phosphatidylinositol-3,4,5-trisphosphate Binding Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Regulation Of Leukocyte Mediated Cytotoxicity Cerebellar Neuron Development Negative Regulation Of Primary MiRNA Processing Negative Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Proliferation Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Intracellular Signal Transduction Plasma Membrane RNA Sequestering Activity Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Response To Wounding Diapedesis Regulation Of Protein Localization To Membrane Response To Hormone Negative Regulation Of Hydrogen Peroxide Metabolic Process Postsynapse To Nucleus Signaling Pathway Interleukin-11-mediated Signaling Pathway Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Interleukin-23-mediated Signaling Pathway T-helper 17 Type Immune Response Glutamatergic Synapse Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose	Ribonucleoprotein Complex Extracellular Exosome Cytosol RNA Binding Macromolecule Metabolic Process Translation Cytosolic Ribosome Macromolecule Biosynthetic Process Cadherin Binding Response To Cytokine Protein Metabolic Process Response To Peptide Secretory Granule Lumen Cellular Response To Cytokine Stimulus Cytoplasmic Translation Membrane Nucleoplasm ATP Hydrolysis Activity Regulation Of Protein Metabolic Process Ribosome Nucleobase-containing Compound Metabolic Process Cytosolic Small Ribosomal Subunit Structural Constituent Of Ribosome Regulation Of Primary Metabolic Process Small Ribosomal Subunit Nucleotide Binding Protein-RNA Complex Assembly Regulation Of Translation ATP Binding Nucleic Acid Metabolic Process Regulation Of Telomere Maintenance Protein Binding Catabolic Process RNA Metabolic Process Positive Regulation Of Cytoplasmic Translation Ficolin-1-rich Granule Lumen Protein-containing Complex Organization Regulation Of RNA Splicing Macromolecule Catabolic Process Cytoplasm Focal Adhesion Positive Regulation Of Biosynthetic Process Nucleus Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Disordered Domain Specific Binding Regulation Of Macromolecule Metabolic Process Ubiquitin Protein Ligase Binding Regulation Of Metabolic Process Post-transcriptional Regulation Of Gene Expression
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