CCDC88A and NDEL1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		CCDC88A	NDEL1
Gene Name		coiled-coil domain containing 88A	nudE neurodevelopment protein 1-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Lamellipodium Cytoplasmic Vesicle	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Nucleolus Cytoplasm Centrosome Spindle Cytosol Kinesin Complex Microtubule Cell Leading Edge Axon Hillock Neurofilament Cytoskeleton
	Molecular Function	Actin Binding Microtubule Binding Phosphatidylinositol Binding Protein Homodimerization Activity Protein Kinase B Binding	Protein Binding Microtubule Binding Alpha-tubulin Binding Beta-tubulin Binding Oligopeptidase Activity
	Biological Process	Regulation Of Protein Phosphorylation DNA Replication Regulation Of DNA Replication Regulation Of Neuron Projection Development Cell Migration Lamellipodium Assembly TOR Signaling Activation Of Protein Kinase B Activity Regulation Of Actin Cytoskeleton Organization Regulation Of Cell Proliferation Membrane Organization	Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Neuron Migration Inner Cell Mass Cell Proliferation Proteolysis Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Retrograde Axon Cargo Transport Regulation Of Neuron Projection Development Cell Migration Cerebral Cortex Radially Oriented Cell Migration Central Nervous System Neuron Axonogenesis Activation Of Cdc42 GTPase Activity Positive Regulation Of Axon Extension Vesicle Transport Along Microtubule Positive Regulation Of Axon Regeneration Nuclear Envelope Disassembly Establishment Of Chromosome Localization Centrosome Localization Neurofilament Cytoskeleton Organization Neuron Projection Extension
Pathways			Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Height ( 21998595)
Protein-Protein Interactions		6 interactors: AKT1 BRAF DISC1 EXOC1 NDEL1 PRKACA	58 interactors: AIMP2 ANK2 APP BMI1 CCDC88A CCHCR1 CCSER1 CCSER2 CDK5 CENPF CEP170 CEP63 CWF19L2 DISC1 DIXDC1 DTNB DYNC1H1 GOLGA2 IMMT KALRN KIFC3 KRT40 LUC7L2 MAGEA11 MBIP MIS18A MLLT10 MRC2 MTUS2 NDC80 NDE1 PAFAH1B1 PKP2 SNAPC5 SNX6 SYNE1 TACC3 TRAF3IP3 TRIM27 USP2 XPA YWHAE YWHAG ZNF10 ZNF17 ZNF180 ZNF197 ZNF211 ZNF230 ZNF260 ZNF264 ZNF417 ZNF490 ZNF544 ZNF572 ZNF599 ZNF844 ZNF91
Entrez ID		55704	81565
HPRD ID		11131	06340
Ensembl ID		ENSG00000115355	ENSG00000166579
Uniprot IDs		O14997 Q3V6T2	Q9GZM8
PDB IDs			2V66
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Differentiation Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Cell Differentiation Positive Regulation Of Blood Vessel Endothelial Cell Migration Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cell Development Membrane Organization Positive Regulation Of Protein Modification Process Nuclear Envelope Disassembly Regulation Of Blood Vessel Endothelial Cell Migration Response To Light Stimulus Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cell Adhesion Regulation Of Neuron Projection Development Regulation Of Protein Catabolic Process Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Transport Regulation Of Cellular Amino Acid Metabolic Process Cerebral Cortex Radially Oriented Cell Migration Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Protein Metabolic Process Nuclear Envelope Organization Regulation Of Glucose Import Positive Regulation Of Signal Transduction Endomembrane System Organization Regulation Of Signal Transduction Response To Radiation Response To Peptide Hormone Positive Regulation Of Protein Kinase Activity Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Projection Organization Response To Peptide Positive Regulation Of Kinase Activity Regulation Of Cellular Ketone Metabolic Process Organ Development Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell Development Regulation Of Endothelial Cell Proliferation Cerebral Cortex Cell Migration Regulation Of Signaling Regulation Of Cell Proliferation Regulation Of Neuron Differentiation Organelle Organization Positive Regulation Of Catalytic Activity Telencephalon Cell Migration Positive Regulation Of Transferase Activity	G2/M Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Cerebral Cortex Development Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Cell Division Pallium Development Cell Cycle Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Telencephalon Development Organelle Organization Cytoskeleton Organization Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Cell Cycle Neural Precursor Cell Proliferation Microtubule-based Process Microtubule Cytoskeleton Organization Forebrain Development Regulation Of Gene Expression Cellular Process Cerebral Cortex Radially Oriented Cell Migration Mitotic Cell Cycle Process Nitrogen Compound Metabolic Process Regulation Of Heart Rate By Cardiac Conduction Organelle Localization Brain Development Neuron Migration Head Development Cerebral Cortex Cell Migration Movement Of Cell Or Subcellular Component Cell Cycle Process Mitotic Nuclear Division Establishment Of Organelle Localization Telencephalon Cell Migration Cardiac Muscle Cell Action Potential Forebrain Cell Migration Cellular Localization
Tagcloud ?			ammonis c57bl ca3 capillary cornu dentate dg disc1 disrupted epilepsy epilepticus erk etiology gyrus hippocampus homolog hypothesize lis1 lissencephaly meanwhile microtubule mitosis organization pilocarpine schizophrenia se seizure spontaneous vessels
Tagcloud (Difference) ?			ammonis c57bl ca3 capillary cornu dentate dg disc1 disrupted epilepsy epilepticus erk etiology gyrus hippocampus homolog hypothesize lis1 lissencephaly meanwhile microtubule mitosis organization pilocarpine schizophrenia se seizure spontaneous vessels
Tagcloud (Intersection) ?