NDEL1 and ZNF230

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		NDEL1	ZNF230
Gene Name		nudE neurodevelopment protein 1-like 1	zinc finger protein 230
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Nucleolus Cytoplasm Centrosome Spindle Cytosol Kinesin Complex Microtubule Cell Leading Edge Axon Hillock Neurofilament Cytoskeleton	Nucleus
	Molecular Function	Protein Binding Microtubule Binding Alpha-tubulin Binding Beta-tubulin Binding Oligopeptidase Activity	DNA Binding Metal Ion Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Neuron Migration Inner Cell Mass Cell Proliferation Proteolysis Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Retrograde Axon Cargo Transport Regulation Of Neuron Projection Development Cell Migration Cerebral Cortex Radially Oriented Cell Migration Central Nervous System Neuron Axonogenesis Activation Of Cdc42 GTPase Activity Positive Regulation Of Axon Extension Vesicle Transport Along Microtubule Positive Regulation Of Axon Regeneration Nuclear Envelope Disassembly Establishment Of Chromosome Localization Centrosome Localization Neurofilament Cytoskeleton Organization Neuron Projection Extension	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Generic Transcription Pathway
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 19684603)
Protein-Protein Interactions		58 interactors: AIMP2 ANK2 APP BMI1 CCDC88A CCHCR1 CCSER1 CCSER2 CDK5 CENPF CEP170 CEP63 CWF19L2 DISC1 DIXDC1 DTNB DYNC1H1 GOLGA2 IMMT KALRN KIFC3 KRT40 LUC7L2 MAGEA11 MBIP MIS18A MLLT10 MRC2 MTUS2 NDC80 NDE1 PAFAH1B1 PKP2 SNAPC5 SNX6 SYNE1 TACC3 TRAF3IP3 TRIM27 USP2 XPA YWHAE YWHAG ZNF10 ZNF17 ZNF180 ZNF197 ZNF211 ZNF230 ZNF260 ZNF264 ZNF417 ZNF490 ZNF544 ZNF572 ZNF599 ZNF844 ZNF91	6 interactors: CCDC136 CCNDBP1 FSD2 KRT40 MDFI NDEL1
Entrez ID		81565	7773
HPRD ID		06340	15754
Ensembl ID		ENSG00000166579	ENSG00000159882
Uniprot IDs		Q9GZM8	Q9UIE0
PDB IDs		2V66
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Cerebral Cortex Development Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Cell Division Pallium Development Cell Cycle Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Telencephalon Development Organelle Organization Cytoskeleton Organization Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Cell Cycle Neural Precursor Cell Proliferation Microtubule-based Process Microtubule Cytoskeleton Organization Forebrain Development Regulation Of Gene Expression Cellular Process Cerebral Cortex Radially Oriented Cell Migration Mitotic Cell Cycle Process Nitrogen Compound Metabolic Process Regulation Of Heart Rate By Cardiac Conduction Organelle Localization Brain Development Neuron Migration Head Development Cerebral Cortex Cell Migration Movement Of Cell Or Subcellular Component Cell Cycle Process Mitotic Nuclear Division Establishment Of Organelle Localization Telencephalon Cell Migration Cardiac Muscle Cell Action Potential Forebrain Cell Migration Cellular Localization	Positive Regulation Of Axon Regeneration Retrograde Axon Cargo Transport Positive Regulation Of Neuron Projection Regeneration Activation Of Cdc42 GTPase Activity Mitotic Centrosome Separation Neurofilament Cytoskeleton Organization Centrosome Separation In Utero Embryonic Development Regulation Of Axon Regeneration Positive Regulation Of Cdc42 GTPase Activity Trophoblast Giant Cell Differentiation Inner Cell Mass Cell Proliferation Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification Microtubule Nucleation Regulation Of Cdc42 GTPase Activity Cytoplasmic Sequestering Of Protein Blastocyst Growth Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Microtubule Polymerization Regulation Of Cdc42 Protein Signal Transduction Centrosome Localization Vesicle Transport Along Microtubule Cell Differentiation Involved In Embryonic Placenta Development Activation Of Rho GTPase Activity Activation Of JUN Kinase Activity Positive Regulation Of Axon Extension Intermediate Filament Cytoskeleton Organization Nuclear Envelope Disassembly Intermediate Filament-based Process Establishment Of Mitotic Spindle Orientation Microtubule Polymerization Or Depolymerization Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Chromosome Localization Negative Regulation Of DNA Binding Axon Cargo Transport Negative Regulation Of Transcription Factor Import Into Nucleus Organelle Transport Along Microtubule Activation Of Ras GTPase Activity Centrosome Cycle Spindle Localization Embryo Development Cerebral Cortex Radially Oriented Cell Migration Neuron Projection Extension Central Nervous System Neuron Axonogenesis Nuclear Envelope Organization Regulation Of Axon Extension Positive Regulation Of JUN Kinase Activity
Tagcloud ?		ammonis c57bl ca3 capillary cornu dentate dg disc1 disrupted epilepsy epilepticus erk etiology gyrus hippocampus homolog hypothesize lis1 lissencephaly meanwhile microtubule mitosis organization pilocarpine schizophrenia se seizure spontaneous vessels
Tagcloud (Difference) ?		ammonis c57bl ca3 capillary cornu dentate dg disc1 disrupted epilepsy epilepticus erk etiology gyrus hippocampus homolog hypothesize lis1 lissencephaly meanwhile microtubule mitosis organization pilocarpine schizophrenia se seizure spontaneous vessels
Tagcloud (Intersection) ?