NDEL1 and SNAPC5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NDEL1	SNAPC5
Description		nudE neurodevelopment protein 1 like 1	small nuclear RNA activating complex polypeptide 5
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Chromosome Cytoplasm Centrosome Microtubule Organizing Center Spindle Cytosol Cytoskeleton Kinesin Complex Microtubule Microtubule Associated Complex Synaptic Vesicle Axon Cell Leading Edge Axon Hillock Neurofilament Cytoskeleton Axon Cytoplasm	Nucleus Nucleoplasm Nucleolus Nuclear Body
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Alpha-tubulin Binding Beta-tubulin Binding	RNA Polymerase III General Transcription Initiation Factor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Neuron Migration Inner Cell Mass Cell Proliferation Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Nervous System Development Retrograde Axonal Transport Insulin Receptor Signaling Pathway Regulation Of Neuron Projection Development Cell Migration Cerebral Cortex Radially Oriented Cell Migration Central Nervous System Neuron Axonogenesis Cell Differentiation Lysosome Localization Regulation Of Intracellular Protein Transport Positive Regulation Of GTPase Activity Vesicle Transport Along Microtubule Chromosome Localization Centrosome Localization Neurofilament Cytoskeleton Organization Radial Glia-guided Pyramidal Neuron Migration Positive Regulation Of Ruffle Assembly Neuron Projection Extension	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS
Interacting Genes		85 interacting genes: ABI3 ACTB AIMP2 AKAP9 ANK2 APP BMI1 BORCS6 BRK1 CASK CCDC88A CCSER1 CDK5 CENPF CEP170 CEP55 CEP63 CWF19L2 DISC1 DIXDC1 DTNB DYNC1H1 DYNLL1 FXR2 GOLGA2 IMMT KALRN KIF19 KIF2C KIF5A KIFC3 KLC4 LUC7L2 MAGEA11 MBIP MED11 MIS18A MLLT10 MRC2 MTUS2 MYO5A NDC80 PAFAH1B1 PARD6G PARVG PICK1 PKP2 PRC1 RBM10 RBM14 RBM5 RPA2 SLAIN1 SNAPC5 SNX6 SYNE1 TACC3 TRAF3IP3 TUBB USP2 XPA YWHAE YWHAG ZC2HC1C ZNF10 ZNF12 ZNF17 ZNF180 ZNF197 ZNF211 ZNF230 ZNF250 ZNF260 ZNF264 ZNF3 ZNF35 ZNF417 ZNF490 ZNF544 ZNF572 ZNF599 ZNF662 ZNF707 ZNF844 ZNF91	43 interacting genes: AMOT ARHGEF38 BATF BFSP2 BLOC1S1 BRCC3 CBY2 CCDC196 CDCA8 CREB5 CREBBP CYTH1 CYTH4 DDIT3 EMILIN1 FAM9C GALR1 GORAB GRIPAP1 HMG20B ITGB3BP JUN LMO2 MBD3L1 MCRS1 MYF5 NDEL1 NMI NOL4 NUDT10 NUP62 POLR2J RNF4 S100Z SNAPC1 SNAPC4 STMN4 TRAPPC2 TRAPPC2B TXLNB ZNF177 ZNF559-ZNF177 ZNRD2
Entrez ID		81565	10302
HPRD ID		06340	16183
Ensembl ID		ENSG00000166579	ENSG00000174446
Uniprot IDs		A6NIZ0 Q9GZM8	O75971
PDB IDs		2V66	7ZWC 7ZWD 7ZX7 7ZX8 7ZXE
Enriched GO Terms of Interacting Partners?		Microtubule-based Process Cytoskeleton Microtubule Cell Division Kinesin Complex Microtubule Binding Microtubule Cytoskeleton Organization Cytoskeleton Organization Centrosome Nucleus Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Identical Protein Binding Regulation Of RNA Biosynthetic Process DNA Binding Cytoskeleton-dependent Intracellular Transport Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Maintenance Of Location In Cell Organelle Organization Kinesin Binding Maintenance Of Location Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Cytoplasmic Microtubule Organization Organelle Localization Acetylcholine Receptor Activator Activity Microtubule-based Movement Regulation Of Heart Rate By Cardiac Conduction Metal Ion Binding Establishment Of Organelle Localization Regulation Of Cell Cycle Microtubule Organizing Center Organization Central Region Of Growth Cone Protein Binding Cardiac Conduction Protein Kinase C Binding Retrograde Axonal Transport Presynapse Kinetochore Supramolecular Fiber Organization Maintenance Of Protein Location In Cell Spindle Organization Regulation Of Microtubule Cytoskeleton Organization Cytoplasmic Microtubule Microtubule Motor Activity	SnRNA-activating Protein Complex Peptidyl-lysine Acetylation Protein Binding Integrated Stress Response Signaling RNA Polymerase II Transcription Regulator Complex CAMP Response Element Binding TRAPPII Protein Complex TRAPPIII Protein Complex SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity Positive Regulation Of Mitotic Cytokinesis Centrosome Separation Mitotic Centrosome Separation SnRNA Transcription Regulation Of Mitotic Cytokinesis
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