NDEL1 and LUC7L2

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		NDEL1	LUC7L2
Gene Name		nudE neurodevelopment protein 1-like 1	LUC7-like 2 (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Nucleolus Cytoplasm Centrosome Spindle Cytosol Kinesin Complex Microtubule Cell Leading Edge Axon Hillock Neurofilament Cytoskeleton	U1 SnRNP Nuclear Speck
	Molecular Function	Protein Binding Microtubule Binding Alpha-tubulin Binding Beta-tubulin Binding Oligopeptidase Activity	MRNA Binding Protein Binding Enzyme Binding Poly(A) RNA Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Neuron Migration Inner Cell Mass Cell Proliferation Proteolysis Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Retrograde Axon Cargo Transport Regulation Of Neuron Projection Development Cell Migration Cerebral Cortex Radially Oriented Cell Migration Central Nervous System Neuron Axonogenesis Activation Of Cdc42 GTPase Activity Positive Regulation Of Axon Extension Vesicle Transport Along Microtubule Positive Regulation Of Axon Regeneration Nuclear Envelope Disassembly Establishment Of Chromosome Localization Centrosome Localization Neurofilament Cytoskeleton Organization Neuron Projection Extension	MRNA Splice Site Selection
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: AIMP2 ANK2 APP BMI1 CCDC88A CCHCR1 CCSER1 CCSER2 CDK5 CENPF CEP170 CEP63 CWF19L2 DISC1 DIXDC1 DTNB DYNC1H1 GOLGA2 IMMT KALRN KIFC3 KRT40 LUC7L2 MAGEA11 MBIP MIS18A MLLT10 MRC2 MTUS2 NDC80 NDE1 PAFAH1B1 PKP2 SNAPC5 SNX6 SYNE1 TACC3 TRAF3IP3 TRIM27 USP2 XPA YWHAE YWHAG ZNF10 ZNF17 ZNF180 ZNF197 ZNF211 ZNF230 ZNF260 ZNF264 ZNF417 ZNF490 ZNF544 ZNF572 ZNF599 ZNF844 ZNF91	54 interactors: AIMP2 ALB APP APPBP2 ATF7IP ATRX CADPS CCDC53 CDC37 CDK4 CDK5RAP2 CHD3 EXOC1 FAM173A FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG KIAA1377 KLHL20 LINC00341 LPL MAN2A2 MAP1LC3B NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRPK1 SRPK2 SRSF6 SRSF7 SSFA2 SVIL ULK2 UNC119 YWHAG ZCCHC10
Entrez ID		81565	51631
HPRD ID		06340	17456
Ensembl ID		ENSG00000166579	ENSG00000146963
Uniprot IDs		Q9GZM8	Q9Y383
PDB IDs		2V66
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Cerebral Cortex Development Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Cell Division Pallium Development Cell Cycle Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Telencephalon Development Organelle Organization Cytoskeleton Organization Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Cell Cycle Neural Precursor Cell Proliferation Microtubule-based Process Microtubule Cytoskeleton Organization Forebrain Development Regulation Of Gene Expression Cellular Process Cerebral Cortex Radially Oriented Cell Migration Mitotic Cell Cycle Process Nitrogen Compound Metabolic Process Regulation Of Heart Rate By Cardiac Conduction Organelle Localization Brain Development Neuron Migration Head Development Cerebral Cortex Cell Migration Movement Of Cell Or Subcellular Component Cell Cycle Process Mitotic Nuclear Division Establishment Of Organelle Localization Telencephalon Cell Migration Cardiac Muscle Cell Action Potential Forebrain Cell Migration Cellular Localization	Organelle Organization Establishment Of Localization In Cell Cellular Localization Protein Transport Regulation Of Kinase Activity Establishment Of Protein Localization Cell Cycle Process Anatomical Structure Development Intracellular Transport Cell Cycle Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Developmental Process Regulation Of Protein Kinase Activity Cellular Component Assembly Positive Regulation Of Cell Cycle Regulation Of MRNA Processing Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Development Regulation Of Cell Differentiation Multicellular Organismal Development Regulation Of RNA Splicing Exocytosis Regulation Of Protein Metabolic Process Regulation Of Neurogenesis Establishment Of Cell Polarity Protein Localization Chromatin Organization Retrograde Axon Cargo Transport Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Process Regulation Of Neuron Differentiation Nuclear Export Mitotic Cell Cycle Regulation Of Cell Size Apoptotic Process Axon Cargo Transport Programmed Cell Death Chromosome Organization Organelle Localization Regulation Of Cellular Process Regulation Of Cell Death Positive Regulation Of Mitotic Cell Cycle Phase Transition Cell Death Positive Regulation Of Metabolic Process Death Regulation Of Phosphorylation Positive Regulation Of Cell Cycle Phase Transition Regulation Of Protein Phosphorylation Regulation Of Gene Expression
Tagcloud ?		ammonis c57bl ca3 capillary cornu dentate dg disc1 disrupted epilepsy epilepticus erk etiology gyrus hippocampus homolog hypothesize lis1 lissencephaly meanwhile microtubule mitosis organization pilocarpine schizophrenia se seizure spontaneous vessels	add african alleles americans ankrd17 antihypertensive caucasian caucasians connections cox18 displaying diuretics elevations fto grin3a hctz heterozygotes hydrochlorothiazide hyperuricaemia padi4 pard3b pear pharmacogenomic replicated rs4784333 suggestive thiazide ua uric
Tagcloud (Difference) ?		ammonis c57bl ca3 capillary cornu dentate dg disc1 disrupted epilepsy epilepticus erk etiology gyrus hippocampus homolog hypothesize lis1 lissencephaly meanwhile microtubule mitosis organization pilocarpine schizophrenia se seizure spontaneous vessels	add african alleles americans ankrd17 antihypertensive caucasian caucasians connections cox18 displaying diuretics elevations fto grin3a hctz heterozygotes hydrochlorothiazide hyperuricaemia padi4 pard3b pear pharmacogenomic replicated rs4784333 suggestive thiazide ua uric
Tagcloud (Intersection) ?