NDEL1 and DIXDC1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		NDEL1	DIXDC1
Gene Name		nudE neurodevelopment protein 1-like 1	DIX domain containing 1
Image
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Nucleolus Cytoplasm Centrosome Spindle Cytosol Kinesin Complex Microtubule Cell Leading Edge Axon Hillock Neurofilament Cytoskeleton	Cytosol Focal Adhesion Neuronal Cell Body Protein Complex Axon Terminus
	Molecular Function	Protein Binding Microtubule Binding Alpha-tubulin Binding Beta-tubulin Binding Oligopeptidase Activity	Actin Binding Protein Binding Protein Domain Specific Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Gamma-tubulin Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Neuron Migration Inner Cell Mass Cell Proliferation Proteolysis Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Retrograde Axon Cargo Transport Regulation Of Neuron Projection Development Cell Migration Cerebral Cortex Radially Oriented Cell Migration Central Nervous System Neuron Axonogenesis Activation Of Cdc42 GTPase Activity Positive Regulation Of Axon Extension Vesicle Transport Along Microtubule Positive Regulation Of Axon Regeneration Nuclear Envelope Disassembly Establishment Of Chromosome Localization Centrosome Localization Neurofilament Cytoskeleton Organization Neuron Projection Extension	Cell Cycle Wnt Signaling Pathway Cerebellar Cortex Development Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Neuron Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Axonogenesis Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: AIMP2 ANK2 APP BMI1 CCDC88A CCHCR1 CCSER1 CCSER2 CDK5 CENPF CEP170 CEP63 CWF19L2 DISC1 DIXDC1 DTNB DYNC1H1 GOLGA2 IMMT KALRN KIFC3 KRT40 LUC7L2 MAGEA11 MBIP MIS18A MLLT10 MRC2 MTUS2 NDC80 NDE1 PAFAH1B1 PKP2 SNAPC5 SNX6 SYNE1 TACC3 TRAF3IP3 TRIM27 USP2 XPA YWHAE YWHAG ZNF10 ZNF17 ZNF180 ZNF197 ZNF211 ZNF230 ZNF260 ZNF264 ZNF417 ZNF490 ZNF544 ZNF572 ZNF599 ZNF844 ZNF91	8 interactors: APP ATXN1 AXIN1 CDC5L MAP3K4 NDEL1 ULK2 ZDHHC17
Entrez ID		81565	85458
HPRD ID		06340	16804
Ensembl ID		ENSG00000166579	ENSG00000150764
Uniprot IDs		Q9GZM8	E9PRV4 Q155Q3 Q86SR7
PDB IDs		2V66	3PZ7
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Cerebral Cortex Development Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Cell Division Pallium Development Cell Cycle Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Telencephalon Development Organelle Organization Cytoskeleton Organization Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Cell Cycle Neural Precursor Cell Proliferation Microtubule-based Process Microtubule Cytoskeleton Organization Forebrain Development Regulation Of Gene Expression Cellular Process Cerebral Cortex Radially Oriented Cell Migration Mitotic Cell Cycle Process Nitrogen Compound Metabolic Process Regulation Of Heart Rate By Cardiac Conduction Organelle Localization Brain Development Neuron Migration Head Development Cerebral Cortex Cell Migration Movement Of Cell Or Subcellular Component Cell Cycle Process Mitotic Nuclear Division Establishment Of Organelle Localization Telencephalon Cell Migration Cardiac Muscle Cell Action Potential Forebrain Cell Migration Cellular Localization	Developmental Cell Growth Developmental Growth Involved In Morphogenesis Cell Growth Regulation Of Signal Transduction Developmental Growth Regulation Of Developmental Growth Regulation Of Signaling Axon Cargo Transport Response To Light Stimulus Neuron Projection Extension Visual Learning Visual Behavior Positive Regulation Of JUN Kinase Activity Signaling Neuron Differentiation Cell Communication Forebrain Development Regulation Of JUN Kinase Activity Associative Learning Wnt-activated Signaling Pathway Involved In Forebrain Neuron Fate Commitment Canonical Wnt Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Response To Radiation Growth Regulation Of Phosphorylation Axonogenesis System Development Regulation Of Neuron Differentiation Adult Locomotory Behavior Synaptic Growth At Neuromuscular Junction Male Germ-line Sex Determination Axon Development RNA Processing Positive Regulation Of JNK Cascade Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cell Size Microtubule-based Transport Regulation Of Phosphorus Metabolic Process Regulation Of Growth Positive Regulation Of Stress-activated MAPK Cascade Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Learning Intracellular Transport Positive Regulation Of Catalytic Activity Activation Of MAPK Activity Neuron Projection Morphogenesis Collateral Sprouting In Absence Of Injury Primary Sex Determination Axial Mesoderm Formation Generation Of Neurons
Tagcloud ?		ammonis c57bl ca3 capillary cornu dentate dg disc1 disrupted epilepsy epilepticus erk etiology gyrus hippocampus homolog hypothesize lis1 lissencephaly meanwhile microtubule mitosis organization pilocarpine schizophrenia se seizure spontaneous vessels	angiogenic array catenin gained gsk3beta hey huaier invasiveness ip1 kill knocking lrp6 mobility motility murr ovarian phosphorylations popularity robiniophila rppa s9 scratch skov3 srb trametes untreated viability wnt5a xenografts
Tagcloud (Difference) ?		ammonis c57bl ca3 capillary cornu dentate dg disc1 disrupted epilepsy epilepticus erk etiology gyrus hippocampus homolog hypothesize lis1 lissencephaly meanwhile microtubule mitosis organization pilocarpine schizophrenia se seizure spontaneous vessels	angiogenic array catenin gained gsk3beta hey huaier invasiveness ip1 kill knocking lrp6 mobility motility murr ovarian phosphorylations popularity robiniophila rppa s9 scratch skov3 srb trametes untreated viability wnt5a xenografts
Tagcloud (Intersection) ?