CCDC88A and EXOC1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		CCDC88A	EXOC1
Gene Name		coiled-coil domain containing 88A	exocyst complex component 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Lamellipodium Cytoplasmic Vesicle	Exocyst Cytosol Plasma Membrane Membrane
	Molecular Function	Actin Binding Microtubule Binding Phosphatidylinositol Binding Protein Homodimerization Activity Protein Kinase B Binding	Protein Binding
	Biological Process	Regulation Of Protein Phosphorylation DNA Replication Regulation Of DNA Replication Regulation Of Neuron Projection Development Cell Migration Lamellipodium Assembly TOR Signaling Activation Of Protein Kinase B Activity Regulation Of Actin Cytoskeleton Organization Regulation Of Cell Proliferation Membrane Organization	Exocytosis Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization
Pathways			Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Height ( 21998595)	Cervical cancer ( 23817570)
Protein-Protein Interactions		6 interactors: AKT1 BRAF DISC1 EXOC1 NDEL1 PRKACA	28 interactors: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST GOLGA4 KANSL1 KDM1A KIAA0226 KIAA1551 KIF5A LUC7L2 MACF1 NUF2 RALA RB1CC1 SFR1 SH3BP5 SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO
Entrez ID		55704	55763
HPRD ID		11131	07615
Ensembl ID		ENSG00000115355	ENSG00000090989
Uniprot IDs		O14997 Q3V6T2	Q9NV70
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Differentiation Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Cell Differentiation Positive Regulation Of Blood Vessel Endothelial Cell Migration Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cell Development Membrane Organization Positive Regulation Of Protein Modification Process Nuclear Envelope Disassembly Regulation Of Blood Vessel Endothelial Cell Migration Response To Light Stimulus Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cell Adhesion Regulation Of Neuron Projection Development Regulation Of Protein Catabolic Process Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Transport Regulation Of Cellular Amino Acid Metabolic Process Cerebral Cortex Radially Oriented Cell Migration Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Protein Metabolic Process Nuclear Envelope Organization Regulation Of Glucose Import Positive Regulation Of Signal Transduction Endomembrane System Organization Regulation Of Signal Transduction Response To Radiation Response To Peptide Hormone Positive Regulation Of Protein Kinase Activity Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Projection Organization Response To Peptide Positive Regulation Of Kinase Activity Regulation Of Cellular Ketone Metabolic Process Organ Development Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell Development Regulation Of Endothelial Cell Proliferation Cerebral Cortex Cell Migration Regulation Of Signaling Regulation Of Cell Proliferation Regulation Of Neuron Differentiation Organelle Organization Positive Regulation Of Catalytic Activity Telencephalon Cell Migration Positive Regulation Of Transferase Activity	Golgi To Plasma Membrane Transport Movement Of Cell Or Subcellular Component Regulation Of Cellular Component Organization Locomotion Nervous System Development Post-Golgi Vesicle-mediated Transport Microtubule-based Process Regulation Of Cell Projection Organization Generation Of Neurons Regulation Of Autophagy TOR Signaling Organelle Organization Golgi To Plasma Membrane Protein Transport Neurogenesis Regulation Of Cell Size Regulation Of Cellular Component Size Chemotaxis Intracellular Signal Transduction Cellular Component Assembly Regulation Of Neuron Projection Development Vesicle-mediated Transport Autophagy Cellular Localization Axon Guidance Regulation Of Neurogenesis Positive Regulation Of Axon Extension Autophagic Vacuole Assembly Establishment Of Localization In Cell Regulation Of Primitive Erythrocyte Differentiation Lamellipodium Assembly Involved In Ameboidal Cell Migration Lamellipodium Assembly Microtubule Cytoskeleton Organization Cell Projection Organization Cell Communication Lamellipodium Organization Positive Regulation Of Neural Precursor Cell Proliferation Macroautophagy Cell Projection Morphogenesis Regulation Of Cell Development Extension Of A Leading Process Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Negative Regulation Of SNARE Complex Assembly Cell Part Morphogenesis Cerebral Cortex Radially Oriented Cell Migration Axonogenesis Regulation Of Axon Extension Regulation Of Neuron Differentiation Regulation Of Organelle Organization Cell Cycle Response To External Stimulus Golgi Vesicle Transport
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