PEX26 and PEX19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (fluorescent resonance energy transfer, two hybrid)

		PEX26	PEX19
Description		peroxisomal biogenesis factor 26	peroxisomal biogenesis factor 19
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Cytosol Membrane	Nucleus Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Membrane Brush Border Membrane Protein-containing Complex
	Molecular Function	Protein Binding Protein-membrane Adaptor Activity Protein-containing Complex Binding ATPase Binding	Protein Binding Peroxisome Membrane Targeting Sequence Binding Peroxisome Membrane Class-1 Targeting Sequence Binding ATPase Binding Protein Carrier Chaperone
	Biological Process	Protein Transport Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Receptor Recycling Protein To Membrane Docking Protein Unfolding Protein Import Into Peroxisome Membrane	Protein Folding Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding
Pathways		Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import	ABC transporters in lipid homeostasis Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)	Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS
Interacting Genes		6 interacting genes: PEX1 PEX14 PEX19 PEX5 PEX6 SUFU	39 interacting genes: ABCD1 ABCD2 ABCD3 BCL2L11 CDC25A CDKN2A DLG4 EIF1B F11R FKBP7 GSKIP IFNB1 IL23A IRF3 KIFAP3 NAT8L OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PSORS1C2 PXMP4 SLC25A17 SLC34A1 SLC61A1 SMAD2 SRPK1 STK3 SUOX TMEM54 TXN2
Entrez ID		55670	5824
HPRD ID		10559	02610
Ensembl ID		ENSG00000215193	ENSG00000162735
Uniprot IDs		A0A024R100 A0A0S2Z5M7 Q7Z412	A0A0S2Z497 P40855
PDB IDs			2W85 2WL8 3AJB 3MK4 5LNF
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization To Peroxisome Peroxisomal Membrane Transport Peroxisome Organization Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Unfolding Protein Import Into Peroxisome Matrix Peroxisomal Membrane Receptor Recycling Protein Import Into Peroxisome Matrix, Translocation Intracellular Protein Transmembrane Transport Peroxisome Receptor Metabolic Process Protein Transmembrane Transport Establishment Of Protein Localization To Organelle Peroxisome Membrane Targeting Sequence Binding Intracellular Protein Transport Intracellular Transport Protein Targeting Protein Import Into Peroxisome Matrix, Docking Protein Localization To Organelle Protein Import Into Peroxisome Matrix, Substrate Release Protein Import Into Peroxisome Membrane Cellular Localization Establishment Of Localization In Cell Ubiquitin-modified Protein Reader Activity Protein Carrier Chaperone Protein Transporter Activity Protein Transport Transmembrane Transport Response To Reactive Oxygen Species Establishment Of Protein Localization Organelle Organization Protein-containing Complex Skin Development Intracellular Protein Localization Protein Monoubiquitination Response To Oxidative Stress Response To Polyamine Macromolecule Peroxisome Transport Along Microtubule Negative Regulation Of Lipid Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Regulation Of Cellular Response To Drug Positive Regulation Of Cellular Response To Drug Protein Tetramerization Multicellular Organismal Locomotion Microtubule-based Peroxisome Localization Peroxisome Matrix Targeting Signal-1 Binding Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Positive Regulation Of Response To Drug	Peroxisome Organization Peroxisomal Membrane Peroxisomal Membrane Transport Peroxisome Establishment Of Protein Localization To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Unfolding Intracellular Protein Transmembrane Transport Protein Import Into Peroxisome Matrix, Substrate Release Receptor Recycling Peroxisomal Importomer Complex Protein Transmembrane Transport Long-chain Fatty Acid Import Into Peroxisome Receptor Metabolic Process Protein Import Into Peroxisome Membrane Very Long-chain Fatty Acid Catabolic Process Protein Transmembrane Transporter Activity Establishment Of Protein Localization To Organelle Fatty Acid Oxidation Fatty Acid Catabolic Process Protein Localization To Organelle Lipid Oxidation Cellular Localization Fatty Acyl-CoA Hydrolase Activity Organophosphate Ester Transmembrane Transporter Activity Nucleobase-containing Compound Transmembrane Transporter Activity Cellular Response To Reactive Oxygen Species Long-chain Fatty Acid Transmembrane Transporter Activity Fatty Acid Beta-oxidation Intracellular Transport Protein Monoubiquitination Organelle Organization Sulfur Compound Transmembrane Transporter Activity Amide Transmembrane Transporter Activity Regulation Of Peroxisome Size Peroxisome Membrane Biogenesis Lipid Modification Intracellular Protein Transport Transmembrane Transport Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking Response To Reactive Oxygen Species Fatty Acid Transport Protein-containing Complex ATPase-coupled Transmembrane Transporter Activity Protein To Membrane Docking Very Long-chain Fatty Acid Metabolic Process Intracellular Lipid Transport Protein Binding
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