PEX26 and PEX6

Number of citations of the paper that reports this interaction (PubMedID 12717447)
0

Data Source:
HPRD (in vivo, in vitro)

		PEX26	PEX6
Description		peroxisomal biogenesis factor 26	peroxisomal biogenesis factor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Cytosol Membrane	Photoreceptor Outer Segment Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Membrane Cell Projection Photoreceptor Cell Cilium
	Molecular Function	Protein Binding Protein-membrane Adaptor Activity Protein-containing Complex Binding ATPase Binding	Nucleotide Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Protein-containing Complex Binding Ubiquitin-modified Protein Reader Activity Protein Transporter Activity
	Biological Process	Protein Transport Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Receptor Recycling Protein To Membrane Docking Protein Unfolding Protein Import Into Peroxisome Membrane	Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Unfolding Protein Stabilization
Pathways		Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import	Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)	Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS			Alzheimer's disease in APOE e4+ carriers ( 25778476) Hematocrit ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		6 interacting genes: PEX1 PEX14 PEX19 PEX5 PEX6 SUFU	8 interacting genes: ATF7IP CERS2 PEX1 PEX26 PEX5 RPL27A RPS14 SMAD3
Entrez ID		55670	5190
HPRD ID		10559	03293
Ensembl ID		ENSG00000215193	ENSG00000124587
Uniprot IDs		A0A024R100 A0A0S2Z5M7 Q7Z412	Q13608
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization To Peroxisome Peroxisomal Membrane Transport Peroxisome Organization Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Unfolding Protein Import Into Peroxisome Matrix Peroxisomal Membrane Receptor Recycling Protein Import Into Peroxisome Matrix, Translocation Intracellular Protein Transmembrane Transport Peroxisome Receptor Metabolic Process Protein Transmembrane Transport Establishment Of Protein Localization To Organelle Peroxisome Membrane Targeting Sequence Binding Intracellular Protein Transport Intracellular Transport Protein Targeting Protein Import Into Peroxisome Matrix, Docking Protein Localization To Organelle Protein Import Into Peroxisome Matrix, Substrate Release Protein Import Into Peroxisome Membrane Cellular Localization Establishment Of Localization In Cell Ubiquitin-modified Protein Reader Activity Protein Carrier Chaperone Protein Transporter Activity Protein Transport Transmembrane Transport Response To Reactive Oxygen Species Establishment Of Protein Localization Organelle Organization Protein-containing Complex Skin Development Intracellular Protein Localization Protein Monoubiquitination Response To Oxidative Stress Response To Polyamine Macromolecule Peroxisome Transport Along Microtubule Negative Regulation Of Lipid Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Regulation Of Cellular Response To Drug Positive Regulation Of Cellular Response To Drug Protein Tetramerization Multicellular Organismal Locomotion Microtubule-based Peroxisome Localization Peroxisome Matrix Targeting Signal-1 Binding Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Positive Regulation Of Response To Drug	Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Unfolding Establishment Of Protein Localization To Peroxisome Peroxisomal Membrane Transport Peroxisome Organization Receptor Recycling Intracellular Protein Transmembrane Transport Receptor Metabolic Process Protein Import Into Peroxisome Membrane Peroxisomal Membrane Protein Transmembrane Transport Protein Targeting To Peroxisome Peroxisome Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Negative Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration Cytosol Establishment Of Protein Localization To Organelle Positive Regulation Of Transforming Growth Factor Beta3 Production Microtubule-based Peroxisome Localization Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Cytosolic Ribosome Sterol Response Element Binding Paraxial Mesoderm Morphogenesis Peroxisome Targeting Sequence Binding Negative Regulation Of Schwann Cell Migration Cytoplasmic Translation Regulation Of Lung Blood Pressure Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking Intracellular Protein Transport Mesoderm Morphogenesis Immune System Development Structural Constituent Of Ribosome Protein To Membrane Docking Pericardium Development Protein Import Into Peroxisome Matrix, Substrate Release Sphingosine N-acyltransferase Activity Transdifferentiation SMAD Protein Complex Trophoblast Cell Migration Regulation Of Response To Wounding Protein Localization To Organelle Negative Regulation Of Glial Cell Migration DEAD/H-box RNA Helicase Binding Heteromeric SMAD Protein Complex Regulation Of Transforming Growth Factor Beta2 Production Ribosome
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