DAO and DAOA

Number of citations of the paper that reports this interaction (PMID 12364586)
112

Data Source:
HPRD (in vitro, two hybrid)

		DAO	DAOA
Gene Name		D-amino-acid oxidase	D-amino acid oxidase activator
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol	Mitochondrion Golgi Apparatus Perinuclear Region Of Cytoplasm
	Molecular Function	D-amino-acid Oxidase Activity Receptor Binding Protein Binding Protein Dimerization Activity Cofactor Binding FAD Binding	Enzyme Activator Activity Enzyme Binding
	Biological Process	Leucine Metabolic Process Proline Catabolic Process Cellular Nitrogen Compound Metabolic Process D-serine Catabolic Process Dopamine Biosynthetic Process Small Molecule Metabolic Process Glyoxylate Metabolic Process Oxidation-reduction Process D-alanine Catabolic Process D-serine Metabolic Process	Positive Regulation Of Catalytic Activity Negative Regulation Of D-amino-acid Oxidase Activity
Pathways		Glyoxylate metabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS			Bipolar disorder and schizophrenia ( 20889312) Obesity-related traits ( 23251661) Visceral fat ( 22589738)
Protein-Protein Interactions		5 interactors: AOC1 DAOA EP300 PEX5 PRKAB2	1 interactors: DAO
Entrez ID		1610	267012
HPRD ID		15917	07591
Ensembl ID		ENSG00000110887	ENSG00000182346
Uniprot IDs		P14920	A2T115 P59103
PDB IDs		2DU8 2E48 2E49 2E4A 2E82 2GNZ 3CUK 3G3E 3W4I 3W4J 3W4K 3ZNN 3ZNO 3ZNP 3ZNQ
Enriched GO Terms of Interacting Partners?		Histone H2B Acetylation Cellular Response To Copper Ion Starvation Cellular Response To Azide Negative Regulation Of D-amino-acid Oxidase Activity Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation N-terminal Peptidyl-lysine Acetylation Protein Import Into Peroxisome Matrix, Docking Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Cellular Response To Heparin Regulation Of Tubulin Deacetylation Response To Heparin Cellular Response To Copper Ion Negative Regulation Of Protein Homooligomerization Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Carnitine Shuttle Fatty Acid Metabolic Process Cellular Response To Histamine Negative Regulation Of Protein Oligomerization Positive Regulation By Host Of Viral Transcription Carnitine Transmembrane Transport Oxidation-reduction Process N-terminal Protein Amino Acid Acetylation Carnitine Transport Response To Histamine Mitochondrion Organization Protein Import Into Peroxisome Matrix Transmembrane Transport Cellular Response To Organonitrogen Compound Quaternary Ammonium Group Transport Cellular Response To Organic Substance Cellular Response To Ammonium Ion Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Oxidoreductase Activity Response To Copper Ion Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Monocarboxylic Acid Metabolic Process Very Long-chain Fatty Acid Metabolic Process N-terminal Protein Amino Acid Modification Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Regulation Of Cellular Response To Heat Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Interaction With Symbiont Regulation Of Fatty Acid Biosynthetic Process Monovalent Inorganic Cation Transport	D-alanine Catabolic Process D-serine Catabolic Process D-amino Acid Catabolic Process D-serine Metabolic Process Glyoxylate Metabolic Process Leucine Metabolic Process Proline Catabolic Process Dopamine Biosynthetic Process Serine Family Amino Acid Catabolic Process Catecholamine Biosynthetic Process Dopamine Metabolic Process Proline Metabolic Process Catecholamine Metabolic Process Serine Family Amino Acid Metabolic Process Cellular Aldehyde Metabolic Process Phenol-containing Compound Metabolic Process Cellular Amino Acid Catabolic Process Carboxylic Acid Catabolic Process Alpha-amino Acid Metabolic Process Cellular Amino Acid Metabolic Process Monocarboxylic Acid Metabolic Process
Tagcloud ?		accessory atrophy cerebellar degeneration deprives diameters dorsal fewer inferior io ioc limits mao medial micron mutants neurons olivary olive olivocerebellar p45 pcd pcs po postsynaptic presynaptic purkinje starts virtually	advent alleles bd bipolar captured chip comt covalently disc1 dtnbp1 easily enhancers feasible genetics h3k4me1 h3k9ac immunoprecipitates mark methodologies monomethylated nrg1 pde4b promoters reason seq sz throughput unidentified
Tagcloud (Difference) ?		accessory atrophy cerebellar degeneration deprives diameters dorsal fewer inferior io ioc limits mao medial micron mutants neurons olivary olive olivocerebellar p45 pcd pcs po postsynaptic presynaptic purkinje starts virtually	advent alleles bd bipolar captured chip comt covalently disc1 dtnbp1 easily enhancers feasible genetics h3k4me1 h3k9ac immunoprecipitates mark methodologies monomethylated nrg1 pde4b promoters reason seq sz throughput unidentified
Tagcloud (Intersection) ?