DAO and PEX5

Number of citations of the paper that reports this interaction (PMID 20178365)
7

Data Source:
BioGRID (unspecified method)

		DAO	PEX5
Gene Name		D-amino-acid oxidase	peroxisomal biogenesis factor 5
Image
Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex
	Molecular Function	D-amino-acid Oxidase Activity Receptor Binding Protein Binding Protein Dimerization Activity Cofactor Binding FAD Binding	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Leucine Metabolic Process Proline Catabolic Process Cellular Nitrogen Compound Metabolic Process D-serine Catabolic Process Dopamine Biosynthetic Process Small Molecule Metabolic Process Glyoxylate Metabolic Process Oxidation-reduction Process D-alanine Catabolic Process D-serine Metabolic Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization
Pathways		Glyoxylate metabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS			IgG glycosylation ( 23382691)
Protein-Protein Interactions		5 interactors: AOC1 DAOA EP300 PEX5 PRKAB2	68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772
Entrez ID		1610	5830
HPRD ID		15917	02684
Ensembl ID		ENSG00000110887	ENSG00000139197
Uniprot IDs		P14920	B4DR50 B4E0T2 P50542
PDB IDs		2DU8 2E48 2E49 2E4A 2E82 2GNZ 3CUK 3G3E 3W4I 3W4J 3W4K 3ZNN 3ZNO 3ZNP 3ZNQ	1FCH 2C0L 2C0M 2J9Q 2W84 3R9A
Enriched GO Terms of Interacting Partners?		Histone H2B Acetylation Cellular Response To Copper Ion Starvation Cellular Response To Azide Negative Regulation Of D-amino-acid Oxidase Activity Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation N-terminal Peptidyl-lysine Acetylation Protein Import Into Peroxisome Matrix, Docking Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Cellular Response To Heparin Regulation Of Tubulin Deacetylation Response To Heparin Cellular Response To Copper Ion Negative Regulation Of Protein Homooligomerization Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Carnitine Shuttle Fatty Acid Metabolic Process Cellular Response To Histamine Negative Regulation Of Protein Oligomerization Positive Regulation By Host Of Viral Transcription Carnitine Transmembrane Transport Oxidation-reduction Process N-terminal Protein Amino Acid Acetylation Carnitine Transport Response To Histamine Mitochondrion Organization Protein Import Into Peroxisome Matrix Transmembrane Transport Cellular Response To Organonitrogen Compound Quaternary Ammonium Group Transport Cellular Response To Organic Substance Cellular Response To Ammonium Ion Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Oxidoreductase Activity Response To Copper Ion Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Monocarboxylic Acid Metabolic Process Very Long-chain Fatty Acid Metabolic Process N-terminal Protein Amino Acid Modification Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Regulation Of Cellular Response To Heat Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Interaction With Symbiont Regulation Of Fatty Acid Biosynthetic Process Monovalent Inorganic Cation Transport	Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process
Tagcloud ?		accessory atrophy cerebellar degeneration deprives diameters dorsal fewer inferior io ioc limits mao medial micron mutants neurons olivary olive olivocerebellar p45 pcd pcs po postsynaptic presynaptic purkinje starts virtually	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?		accessory atrophy cerebellar degeneration deprives diameters dorsal fewer inferior io ioc limits mao medial micron mutants neurons olivary olive olivocerebellar p45 pcd pcs po postsynaptic presynaptic purkinje starts virtually	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?