DAO and AOC1

Number of citations of the paper that reports this interaction (PMID 8195119)
1

Data Source:
HPRD (in vivo)

		DAO	AOC1
Gene Name		D-amino-acid oxidase	amine oxidase, copper containing 1
Image
Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol	Extracellular Space Peroxisome Plasma Membrane Tight Junction Extracellular Vesicular Exosome
	Molecular Function	D-amino-acid Oxidase Activity Receptor Binding Protein Binding Protein Dimerization Activity Cofactor Binding FAD Binding	Receptor Activity Cation Channel Activity Sodium Channel Activity Copper Ion Binding Calcium Ion Binding Primary Amine Oxidase Activity Drug Binding Heparin Binding Zinc Ion Binding Protein Complex Binding Protein Homodimerization Activity Quinone Binding Diamine Oxidase Activity Histamine Oxidase Activity Methylputrescine Oxidase Activity Propane-1,3-diamine Oxidase Activity
	Biological Process	Leucine Metabolic Process Proline Catabolic Process Cellular Nitrogen Compound Metabolic Process D-serine Catabolic Process Dopamine Biosynthetic Process Small Molecule Metabolic Process Glyoxylate Metabolic Process Oxidation-reduction Process D-alanine Catabolic Process D-serine Metabolic Process	Amine Metabolic Process Sodium Ion Transmembrane Transport Cellular Response To Copper Ion Starvation Response To Drug Response To Antibiotic Oxidation-reduction Process Cellular Response To Copper Ion Cellular Response To Histamine Cellular Response To Heparin Cellular Response To Azide
Pathways		Glyoxylate metabolism Metabolism of amino acids and derivatives
Drugs			Amiloride Diminazene
Diseases
GWAS
Protein-Protein Interactions		5 interactors: AOC1 DAOA EP300 PEX5 PRKAB2	3 interactors: DAO DNM2 FGD1
Entrez ID		1610	26
HPRD ID		15917	00088
Ensembl ID		ENSG00000110887	ENSG00000002726
Uniprot IDs		P14920	C9J690 P19801
PDB IDs		2DU8 2E48 2E49 2E4A 2E82 2GNZ 3CUK 3G3E 3W4I 3W4J 3W4K 3ZNN 3ZNO 3ZNP 3ZNQ	3HI7 3HIG 3HII 3K5T 3MPH
Enriched GO Terms of Interacting Partners?		Histone H2B Acetylation Cellular Response To Copper Ion Starvation Cellular Response To Azide Negative Regulation Of D-amino-acid Oxidase Activity Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation N-terminal Peptidyl-lysine Acetylation Protein Import Into Peroxisome Matrix, Docking Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Cellular Response To Heparin Regulation Of Tubulin Deacetylation Response To Heparin Cellular Response To Copper Ion Negative Regulation Of Protein Homooligomerization Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Carnitine Shuttle Fatty Acid Metabolic Process Cellular Response To Histamine Negative Regulation Of Protein Oligomerization Positive Regulation By Host Of Viral Transcription Carnitine Transmembrane Transport Oxidation-reduction Process N-terminal Protein Amino Acid Acetylation Carnitine Transport Response To Histamine Mitochondrion Organization Protein Import Into Peroxisome Matrix Transmembrane Transport Cellular Response To Organonitrogen Compound Quaternary Ammonium Group Transport Cellular Response To Organic Substance Cellular Response To Ammonium Ion Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Oxidoreductase Activity Response To Copper Ion Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Monocarboxylic Acid Metabolic Process Very Long-chain Fatty Acid Metabolic Process N-terminal Protein Amino Acid Modification Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Regulation Of Cellular Response To Heat Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Interaction With Symbiont Regulation Of Fatty Acid Biosynthetic Process Monovalent Inorganic Cation Transport	D-serine Catabolic Process D-alanine Catabolic Process Negative Regulation Of Membrane Tubulation D-amino Acid Catabolic Process D-serine Metabolic Process Glyoxylate Metabolic Process Leucine Metabolic Process Proline Catabolic Process Regulation Of Cell Morphogenesis Dopamine Biosynthetic Process Positive Regulation Of Apoptotic Process Serine Family Amino Acid Catabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Filopodium Assembly Catecholamine Biosynthetic Process Regulation Of Cdc42 GTPase Activity Nitric Oxide Metabolic Process Dopamine Metabolic Process Proline Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of Cdc42 Protein Signal Transduction Transferrin Transport Regulation Of Nitric-oxide Synthase Activity Catecholamine Metabolic Process Receptor Internalization Cell Projection Organization Serine Family Amino Acid Metabolic Process Regulation Of Axon Extension Cellular Aldehyde Metabolic Process Regulation Of Oxidoreductase Activity Iron Ion Transport Receptor Metabolic Process Regulation Of Apoptotic Process Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Regulation Of Cell Death Phenol-containing Compound Metabolic Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Synaptic Vesicle Transport Reactive Oxygen Species Metabolic Process
Tagcloud ?		accessory atrophy cerebellar degeneration deprives diameters dorsal fewer inferior io ioc limits mao medial micron mutants neurons olivary olive olivocerebellar p45 pcd pcs po postsynaptic presynaptic purkinje starts virtually	adipocytes amine aoc2 aoc3 aos benzylamine diamine glycerol histamine histaminergic ileum invalidation ko lipolysis lipolytic mao maoa maob oxidases oxidation oxidized peroxide reaching rodent semicarbazide ssao visceral
Tagcloud (Difference) ?		accessory atrophy cerebellar degeneration deprives diameters dorsal fewer inferior io ioc limits medial micron mutants neurons olivary olive olivocerebellar p45 pcd pcs po postsynaptic presynaptic purkinje starts virtually	adipocytes amine aoc2 aoc3 aos benzylamine diamine glycerol histamine histaminergic ileum invalidation ko lipolysis lipolytic maoa maob oxidases oxidation oxidized peroxide reaching rodent semicarbazide ssao visceral
Tagcloud (Intersection) ?		mao