ASAP3 and PDZD3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ASAP3	PDZD3
Gene Name		ArfGAP with SH3 domain, ankyrin repeat and PH domain 3	PDZ domain containing 3
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Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Focal Adhesion	Cytosol Brush Border Subapical Complex Apical Part Of Cell
	Molecular Function	ARF GTPase Activator Activity Zinc Ion Binding	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity
	Biological Process	Cell Migration Positive Regulation Of ARF GTPase Activity Regulation Of Stress Fiber Assembly	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance CGMP-mediated Signaling Negative Regulation Of CGMP Biosynthetic Process Negative Regulation Of Guanylate Cyclase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ARF6 PDZD3 REL TFCP2 UBE3A	17 interactors: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7
Entrez ID		55616	79849
HPRD ID		11662	06191
Ensembl ID		ENSG00000088280	ENSG00000172367
Uniprot IDs		B4DRP2 Q8TDY4	B0YJ61 Q86UT5
PDB IDs		2B0O 3LVQ 3LVR	2V90
Enriched GO Terms of Interacting Partners?		Negative Regulation Of CGMP Biosynthetic Process Sperm Entry Negative Regulation Of Guanylate Cyclase Activity	Transmembrane Transport Ion Transport Ion Transmembrane Transport Sodium-independent Organic Anion Transport Anion Transport Organic Anion Transport Anion Transmembrane Transport Drug Transport Monocarboxylic Acid Transport Quaternary Ammonium Group Transport Transport Cation Transmembrane Transport Drug Transmembrane Transport Carboxylic Acid Transport Organic Acid Transport Antibiotic Transport Toxin Transport Ammonium Transmembrane Transport Organic Cation Transport Cation Transport Oligopeptide Transport Ammonium Transport Response To Drug Inorganic Anion Transport Carnitine Transmembrane Transport Carnitine Transport Lipid Transport Lipid Localization Monovalent Inorganic Cation Transport Dipeptide Transport Histamine Uptake Positive Regulation Of ARF GTPase Activity Short-chain Fatty Acid Import Positive Regulation Of Voltage-gated Chloride Channel Activity Positive Regulation Of Intestinal Epithelial Structure Maintenance Quorum Sensing Involved In Interaction With Host Sodium-dependent Organic Cation Transport Fatty Acid Transport Regulation Of Intestinal Epithelial Structure Maintenance Prostaglandin Transport Peptide Transport Hormone Transport Extraocular Skeletal Muscle Development Oligopeptide Transmembrane Transport Regulation Of Chloride Transport Amide Transport Iodide Transport Thyroid Hormone Transport Transepithelial Chloride Transport Cellular Chloride Ion Homeostasis
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