ASAP3

Description		ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
Image
GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Cell Migration Positive Regulation Of GTPase Activity Regulation Of Stress Fiber Assembly
Pathways
Drugs
Diseases
GWAS		Cholesterol, total ( 24097068) LDL cholesterol levels ( 32203549) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Severe insulin-resistant type 2 diabetes ( 34737425) Total cholesterol levels ( 28334899) Triglyceride levels ( 32203549)
Interacting Genes		9 interacting genes: ARF6 CRK MTNR1A NHERF4 REL TCF4 TEPSIN TFCP2 UBE3A
Entrez ID		55616
HPRD ID		11662
Ensembl ID		ENSG00000088280
Uniprot IDs		A0AAA9YHE6 B4DRP2 Q8TDY4
PDB IDs		2B0O 3LVQ 3LVR
Enriched GO Terms of Interacting Partners?		Response To Nerve Growth Factor Postsynaptic Specialization Organization Regulation Of Rac Protein Signal Transduction Erythrocyte Apoptotic Process Protein Localization To Membrane Cellular Response To Nerve Growth Factor Stimulus Sperm Entry Positive Regulation Of Golgi Lumen Acidification Guanylate Cyclase Inhibitor Activity Coated Vesicle Membrane Signaling Adaptor Activity Positive Regulation Of Protein Localization To Membrane Establishment Of Cell Polarity Regulation Of Dendrite Development Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Positive Regulation Of Protein Localization Protein Localization To Cleavage Furrow Cerebellar Neuron Development DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Beta-catenin-TCF7L2 Complex Regulation Of Golgi Lumen Acidification Regulation Of Intracellular Signal Transduction Localization Within Membrane Melatonin Receptor Activity NF-kappaB Complex TFIIB-class Transcription Factor Binding
Tagcloud ?