DACH1 and AHCYL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DACH1	AHCYL1
Gene Name		dachshund family transcription factor 1	adenosylhomocysteinase-like 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Cytosol Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Factor Activity Involved In Preinitiation Complex Assembly RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Protein Binding	Adenosylhomocysteinase Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Suckling Behavior Respiratory Gaseous Exchange Cell Proliferation Negative Regulation Of Transcription By Competitive Promoter Binding Negative Regulation Of Cell Migration Development Of Primary Female Sexual Characteristics Negative Regulation Of Fibroblast Proliferation RNA Polymerase II Transcriptional Preinitiation Complex Assembly Negative Regulation Of Cell Proliferation Involved In Contact Inhibition	MRNA Polyadenylation Protein Export From Nucleus One-carbon Metabolic Process Biological_process Positive Regulation Of Sodium Ion Transport Regulation Of MRNA 3'-end Processing Regulation Of Ion Transmembrane Transporter Activity S-adenosylmethionine Cycle Regulation Of Anion Transport
Pathways
Drugs
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Chronic kidney disease ( 20383146) Longevity ( 20834067) Obsessive-compulsive disorder ( 22889921) Urate levels ( 23263486)
Protein-Protein Interactions		18 interactors: AHCYL1 C1orf35 CREBBP EYA1 EYA3 FGF12 JUN NAGK NCOR1 PPIG RNF14 SIN3A SIX1 SMAD3 SMAD4 U2AF2 UBE2I ZCCHC10	14 interactors: BID CDKN2C DACH1 GEM HGS ITPR1 MEOX2 PPL PSMD9 SLC23A1 SOX30 SRPK1 SRPK2 ZNF165
Entrez ID		1602	10768
HPRD ID		16031	07613
Ensembl ID		ENSG00000165659	ENSG00000168710
Uniprot IDs		Q9UI36	O43865
PDB IDs		1L8R	3MTG
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Heart Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heart Development Positive Regulation Of Transcription, DNA-templated Ureteric Bud Development Negative Regulation Of Biosynthetic Process Mesonephric Tubule Development Mesonephric Epithelium Development Regulation Of Heart Morphogenesis Mesonephros Development Cellular Metabolic Process Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Secondary Heart Field Cardioblast Proliferation Macromolecule Biosynthetic Process Kidney Epithelium Development Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of DNA-templated Transcription In Response To Stress SMAD Protein Signal Transduction Histone Dephosphorylation Response To Transforming Growth Factor Beta Branching Involved In Ureteric Bud Morphogenesis Outflow Tract Morphogenesis	Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Regulation Of Metabolic Process Intracellular Signal Transduction Nuclear Speck Organization Transepithelial L-ascorbic Acid Transport Neuron Death Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Developmental Process Regulation Of Cell Proliferation L-ascorbic Acid Transport Molecular Hydrogen Transport Regulation Of MRNA Processing Signal Transduction In Response To DNA Damage Regulation Of RNA Splicing Regulation Of Cell Cycle Gene Expression RNA Polymerase II Transcriptional Preinitiation Complex Assembly Proteasome Regulatory Particle Assembly Multicellular Organismal Development Nucleus Organization Voluntary Musculoskeletal Movement Dehydroascorbic Acid Transport Regulation Of Cellular Localization Cell Death Death Regulation Of Gene Expression Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Cellular Nitrogen Compound Metabolic Process Nucleobase Transport Somite Specification Regulation Of Viral Process G1/S Transition Of Mitotic Cell Cycle Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Glial Cell Apoptotic Process Negative Regulation Of Calcium-mediated Signaling Intrinsic Apoptotic Signaling Pathway Immune Response Cellular Macromolecular Complex Assembly Negative Regulation Of Transcription By Competitive Promoter Binding Sperm Chromatin Condensation Positive Regulation Of Protein Homooligomerization Regulation Of Secretion Immune System Process
Tagcloud ?		atlas basal bcl2 call chip conclusionthe considerations depend deregulation focused gata3 introductiongata3 luminal mammary methodsgata3 mutated proper regard representing resultswe seq shared shift signatures special subgroup suppressing thsd4 tumorigenesis	abnormality accession attempt csf1 elicit exon exons fused fusion giant karyotypic kb nos nt p11 pathogenetic q21 replaced replacement s100a10 sole stop tag tenosynovial theme transcript tsgct untranslated utr
Tagcloud (Difference) ?		atlas basal bcl2 call chip conclusionthe considerations depend deregulation focused gata3 introductiongata3 luminal mammary methodsgata3 mutated proper regard representing resultswe seq shared shift signatures special subgroup suppressing thsd4 tumorigenesis	abnormality accession attempt csf1 elicit exon exons fused fusion giant karyotypic kb nos nt p11 pathogenetic q21 replaced replacement s100a10 sole stop tag tenosynovial theme transcript tsgct untranslated utr
Tagcloud (Intersection) ?