DACH1 and RNF14

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DACH1	RNF14
Gene Name		dachshund family transcription factor 1	ring finger protein 14
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Factor Activity Involved In Preinitiation Complex Assembly RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Protein Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Androgen Receptor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Suckling Behavior Respiratory Gaseous Exchange Cell Proliferation Negative Regulation Of Transcription By Competitive Promoter Binding Negative Regulation Of Cell Migration Development Of Primary Female Sexual Characteristics Negative Regulation Of Fibroblast Proliferation RNA Polymerase II Transcriptional Preinitiation Complex Assembly Negative Regulation Of Cell Proliferation Involved In Contact Inhibition	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Protein Ubiquitination Androgen Receptor Signaling Pathway Response To Estradiol Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Chronic kidney disease ( 20383146) Longevity ( 20834067) Obsessive-compulsive disorder ( 22889921) Urate levels ( 23263486)
Protein-Protein Interactions		18 interactors: AHCYL1 C1orf35 CREBBP EYA1 EYA3 FGF12 JUN NAGK NCOR1 PPIG RNF14 SIN3A SIX1 SMAD3 SMAD4 U2AF2 UBE2I ZCCHC10	22 interactors: AR DACH1 ESR1 FAM46A HNF1A HNRNPA1 NCOA4 NR3C1 PHF7 TAGLN TNFAIP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2U UBE2V1 UBE2W VDR
Entrez ID		1602	9604
HPRD ID		16031	05745
Ensembl ID		ENSG00000165659	ENSG00000013561
Uniprot IDs		Q9UI36	B7Z229 Q9UBS8
PDB IDs		1L8R
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Heart Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heart Development Positive Regulation Of Transcription, DNA-templated Ureteric Bud Development Negative Regulation Of Biosynthetic Process Mesonephric Tubule Development Mesonephric Epithelium Development Regulation Of Heart Morphogenesis Mesonephros Development Cellular Metabolic Process Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Secondary Heart Field Cardioblast Proliferation Macromolecule Biosynthetic Process Kidney Epithelium Development Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of DNA-templated Transcription In Response To Stress SMAD Protein Signal Transduction Histone Dephosphorylation Response To Transforming Growth Factor Beta Branching Involved In Ureteric Bud Morphogenesis Outflow Tract Morphogenesis	Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Protein K63-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Intracellular Steroid Hormone Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Steroid Hormone Mediated Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Innate Immune Response Response To Organic Substance Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Hormone-mediated Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Protein Monoubiquitination Cellular Protein Catabolic Process Mammary Gland Branching Involved In Pregnancy Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Protein Catabolic Process Cellular Response To Organic Substance Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress ISG15-protein Conjugation Regulation Of DNA-templated Transcription In Response To Stress Mammary Gland Duct Morphogenesis Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Lipid TRIF-dependent Toll-like Receptor Signaling Pathway Cellular Protein Modification Process Cellular Response To Stress Developmental Process Involved In Reproduction MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
Tagcloud ?		atlas basal bcl2 call chip conclusionthe considerations depend deregulation focused gata3 introductiongata3 luminal mammary methodsgata3 mutated proper regard representing resultswe seq shared shift signatures special subgroup suppressing thsd4 tumorigenesis
Tagcloud (Difference) ?		atlas basal bcl2 call chip conclusionthe considerations depend deregulation focused gata3 introductiongata3 luminal mammary methodsgata3 mutated proper regard representing resultswe seq shared shift signatures special subgroup suppressing thsd4 tumorigenesis
Tagcloud (Intersection) ?