CDKN2C and SCGB2A2

Number of citations of the paper that reports this interaction (PubMedID 25640309)
0

Data Source:
BioGRID (two hybrid)

		CDKN2C	SCGB2A2
Description		cyclin dependent kinase inhibitor 2C	secretoglobin family 2A member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Extracellular Region Extracellular Space
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein Kinase Binding	Protein Binding
	Biological Process	Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth Oligodendrocyte Differentiation Stem Cell Proliferation Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Stem Cell Proliferation	Androgen Receptor Signaling Pathway
Pathways		Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Cyclin D associated events in G1
Drugs
Diseases
GWAS		Atrial fibrillation ( 29290336) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cataracts ( 34127677) Cataracts (operation) ( 31816047) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 33713608 31562340) Hip circumference adjusted for BMI ( 34021172) Hippocampal tail volume (corrected for total hippocampal volume) ( 30279459) Ischemic stroke (large artery atherosclerosis) ( 26732560) Male-pattern baldness ( 28196072) Pulse pressure ( 30578418) QRS complex (12-leadsum) ( 27659466) QRS duration ( 27577874 21076409 27659466) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Thyroid stimulating hormone levels ( 32769997) Ventricular ectopy ( 29618737) Ventricular ectopy or supraventricular ectopy (pleiotropy) ( 29618737)	HIV-1 viral setpoint ( 26039976) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		59 interacting genes: AHCYL1 AKT1 ANGPTL4 APLP1 ARNT ATM ATR CCDC90B CCND2 CCNE1 CDK4 CDK6 CDKN2A CDKN2B COPS6 CRX CTDSP1 DRAP1 EPHA2 ERBB2 FGFR4 GDF9 GOPC GREB1 GRM1 KRT31 LATS2 LNX2 LRIF1 LY96 MAP2K3 MAP2K5 MAPK10 MAPK8 MTA3 MYC NAGK NAT2 NF2 NIF3L1 PBX4 PDGFRA PLEKHG4 POU6F2 PPP2CA RAF1 RBM48 REL SCGB2A2 SNU13 SORBS3 ST14 STK11 TCF12 TCF4 TLE1 TP53 UBC UNC119	6 interacting genes: CASP8 CDKN2C LSP1 SCGB1D2 TREM2 VASP
Entrez ID		1031	4250
HPRD ID		04534	05712
Ensembl ID		ENSG00000123080	ENSG00000110484
Uniprot IDs		P42773 Q6ICV4	Q13296 Q6NX70
PDB IDs		1BU9 1G3N 1IHB 1MX2 1MX4 1MX6
Enriched GO Terms of Interacting Partners?		Kinase Activity Protein Kinase Activity Regulation Of Mitotic Cell Cycle Phase Transition Protein Serine Kinase Activity Regulation Of Cell Cycle Phase Transition Cellular Senescence Phosphorylation Protein Serine/threonine Kinase Activity Regulation Of Mitotic Cell Cycle Protein Phosphorylation Intracellular Signal Transduction Mitotic Cell Cycle Phase Transition Regulation Of Primary Metabolic Process Regulation Of Epithelial Cell Proliferation Regulation Of Cell Cycle Regulation Of Intracellular Signal Transduction Regulation Of G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Signal Transduction MAPK Cascade Regulation Of Cell Cycle Process Replicative Senescence Positive Regulation Of Signal Transduction Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Macromolecule Metabolic Process Response To Radiation Regulation Of Cell Population Proliferation G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Regulation Of RNA Metabolic Process Regulation Of Signal Transduction Intracellular Signaling Cassette Positive Regulation Of Intracellular Signal Transduction Regulation Of Metabolic Process Positive Regulation Of Cell Communication Response To UV Positive Regulation Of Signaling Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Response To Light Stimulus Cellular Response To Radiation Regulation Of Signaling Regulation Of Cell Communication ATP Binding Regulation Of Catalytic Activity Regulation Of Transcription By RNA Polymerase II Regulation Of Phosphorus Metabolic Process Regulation Of Cell Cycle G2/M Phase Transition	Positive Regulation Of Proteolysis Response To Anesthetic Negative Regulation Of Canonical NF-kappaB Signal Transduction Ripoptosome Regulation Of Interleukin-1 Production Death Effector Domain Binding Regulation Of Myeloid Leukocyte Differentiation Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Pyroptotic Inflammatory Response Positive Regulation Of Leukocyte Differentiation CD95 Death-inducing Signaling Complex Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Myeloid Cell Differentiation Scaffold Protein Binding Lamellipodium Regulation Of Cytokine-mediated Signaling Pathway Myeloid Leukocyte Differentiation Positive Regulation Of Inflammatory Response Regulation Of Interleukin-1 Beta Production Positive Regulation Of CD40 Signaling Pathway Positive Regulation Of Engulfment Of Apoptotic Cell Positive Regulation Of Macrophage Fusion Positive Regulation Of C-C Chemokine Receptor CCR7 Signaling Pathway Sulfatide Binding Negative Regulation Of Astrocyte Activation CXCL12-activated CXCR4 Signaling Pathway Positive Regulation Of Complement Activation, Classical Pathway Negative Regulation Of Fat Cell Proliferation Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of CD40 Signaling Pathway Positive Regulation Of CAMKK-AMPK Signaling Cascade Respiratory Burst After Phagocytosis Negative Regulation Of Autophagic Cell Death Positive Regulation Of Complement Activation Detection Of Lipoteichoic Acid Detection Of Lipopolysaccharide Excitatory Synapse Pruning Complement-mediated Synapse Pruning Positive Regulation Of Microglial Cell Migration Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Apolipoprotein A-I Binding Positive Regulation Of High-density Lipoprotein Particle Clearance Negative Regulation Of Macrophage Colony-stimulating Factor Signaling Pathway Regulation Of CAMKK-AMPK Signaling Cascade Microglial Cell Activation Involved In Immune Response Regulation Of Astrocyte Activation Very-low-density Lipoprotein Particle Binding Positive Regulation Of Low-density Lipoprotein Particle Clearance Regulation Of Hippocampal Neuron Apoptotic Process Positive Regulation Of Synapse Pruning
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