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YY1AP1 and PRKAB2
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
YY1AP1
PRKAB2
Gene Name
YY1 associated protein 1
protein kinase, AMP-activated, beta 2 non-catalytic subunit
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Nucleoplasm
Cytosol
AMP-activated Protein Kinase Complex
Molecular Function
Protein Binding
AMP-activated Protein Kinase Activity
Protein Binding
Identical Protein Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Cell Cycle
Energy Reserve Metabolic Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Carnitine Shuttle
Organelle Organization
Mitochondrion Organization
Cell Cycle Arrest
Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Fatty Acid Biosynthetic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Regulation Of Protein Kinase Activity
Membrane Organization
Pathways
Organelle biogenesis and maintenance
Integration of energy metabolism
Metabolism of lipids and lipoproteins
Regulation of Rheb GTPase activity by AMPK
IRS-mediated signalling
mTOR signalling
Translocation of GLUT4 to the plasma membrane
Import of palmitoyl-CoA into the mitochondrial matrix
mTOR signalling
IGF1R signaling cascade
IRS-related events triggered by IGF1R
Energy dependent regulation of mTOR by LKB1-AMPK
PKB-mediated events
PI3K Cascade
Signaling by Insulin receptor
Fatty acid, triacylglycerol, and ketone body metabolism
Insulin receptor signalling cascade
Regulation of AMPK activity via LKB1
IRS-related events
Mitochondrial biogenesis
IRS-mediated signalling
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
AMPK inhibits chREBP transcriptional activation activity
PKB-mediated events
PI3K Cascade
Drugs
Adenosine monophosphate
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
ATXN1
ATXN1L
EWSR1
MAD2L2
MAPK14
MAPK8IP2
MDM2
PRKAB2
VHL
ZFAT
70 interactors:
ADAMTSL4
BANP
BEND5
BLZF1
CALCOCO2
CASP6
CCDC33
CCDC36
CDX4
CREB3L1
CRX
CSNK2B
DAO
DDIT4L
DICER1
DST
EPM2A
FAM208B
FDX1
FLNC
GATA1
GATAD2B
GET4
GNB2L1
GOLGA2
GRN
IKZF1
IKZF3
KCTD5
KLF15
KRT40
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-12
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-4
LZTS2
MAGED1
MDFI
MEOX2
NEBL
PIAS2
PRDM14
PRKAA1
PRKAA2
PRKAG1
PRKAG2
PRKAG3
PSME3
PYGM
RBPMS
REL
RHEBL1
RIMBP3
SPRY2
STX11
STX19
TADA2A
TCF4
TP53BP2
TRAF2
TRIM10
UBXN11
YY1AP1
ZBTB32
Entrez ID
55249
5565
HPRD ID
08485
04117
Ensembl ID
ENSG00000163374
ENSG00000131791
Uniprot IDs
B4DQQ0
I6L9C2
Q9H869
O43741
PDB IDs
2F15
2V8Q
2V92
2V9J
2Y8L
2Y8Q
2Y94
2YA3
4EAI
4EAJ
Enriched GO Terms of Interacting Partners
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Regulation Of Transcription From RNA Polymerase II Promoter
Signal Transduction In Response To DNA Damage
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Transcription, DNA-templated
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Phosphorylation
Negative Regulation Of Gene Expression
Positive Regulation Of Metabolic Process
Cell Cycle Checkpoint
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Response To Stress
Cellular Metabolic Process
Lung Alveolus Development
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Excitatory Postsynaptic Membrane Potential
Cellular Response To UV-C
P38MAPK Cascade
Cellular Response To Vitamin B1
Regulation Of Postsynaptic Membrane Potential
Cell Cycle Process
Regulation Of Protein Phosphorylation
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cell Cycle
Negative Regulation Of Signal Transduction
Response To Radiation
Response To Abiotic Stimulus
Posttranscriptional Regulation Of Gene Expression
Cellular Response To Hypoxia
RNA Metabolic Process
Cellular Response To Decreased Oxygen Levels
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Nucleocytoplasmic Transport
Response To Peptide
Biosynthetic Process
Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cell Cycle Arrest
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Glycogen Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Glycolytic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Protein Modification Process
Negative Regulation Of Cell Cycle
Energy Reserve Metabolic Process
Regulation Of Cell Cycle
Regulation Of RNA Metabolic Process
Positive Regulation Of Gene Expression
Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Polysaccharide Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Macromolecule Biosynthetic Process
Organelle Organization
Gene Expression
Cell Cycle Process
Positive Regulation Of Phosphorylation
RNA Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of Protein Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Signaling
Fatty Acid Biosynthetic Process
Cellular Process
Regulation Of Cellular Ketone Metabolic Process
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
Transcription From RNA Polymerase II Promoter
Regulation Of Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Binding
Regulation Of Metabolic Process
Regulation Of Carbohydrate Metabolic Process
Regulation Of Phosphorylation
Regulation Of Generation Of Precursor Metabolites And Energy
Regulation Of Cell Death
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