YY1AP1 and MAPK8IP2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		YY1AP1	MAPK8IP2
Gene Name		YY1 associated protein 1	mitogen-activated protein kinase 8 interacting protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Neuronal Cell Body Protein Complex Neuronal Postsynaptic Density
	Molecular Function	Protein Binding	Beta-amyloid Binding MAP-kinase Scaffold Activity Structural Molecule Activity Protein Binding Kinesin Binding Protein Kinase Binding Protein Kinase Activator Activity Protein Complex Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle	MAPK Cascade Behavioral Fear Response Signal Complex Assembly JNK Cascade Mating Behavior Regulation Of Receptor Activity Positive Regulation Of Stress-activated MAPK Cascade Social Behavior Positive Regulation Of Protein Kinase Activity Regulation Of JNK Cascade Nonassociative Learning Dendrite Morphogenesis Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ATXN1 ATXN1L EWSR1 MAD2L2 MAPK14 MAPK8IP2 MDM2 PRKAB2 VHL ZFAT	52 interactors: ADRB2 AFG3L2 APP ASRGL1 BBS10 C14orf1 CFL1 CHN1 CRMP1 DUSP16 EGFR ERBB2 EZH2 FGF12 FSCN1 GBP2 ITSN1 KIFC2 KLC1 LRP1 LRP2 LRP8 MAGED4B MAP2K3 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAPK10 MAPK8 MAPK8IP1 MAPK8IP3 MAPK9 MASP1 NDUFS6 PLXNA3 PRSS23 RAI1 RBX1 RPS6KB2 SMARCB1 SMS SYNE2 TIAM1 TP53BP2 UNC119 VCP VPS33B VRK2 YY1AP1 ZNF593 ZNF784
Entrez ID		55249	23542
HPRD ID		08485	09674
Ensembl ID		ENSG00000163374	ENSG00000008735
Uniprot IDs		B4DQQ0 I6L9C2 Q9H869	Q13387
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction In Response To DNA Damage Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Phosphorylation Negative Regulation Of Gene Expression Positive Regulation Of Metabolic Process Cell Cycle Checkpoint Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Cellular Metabolic Process Lung Alveolus Development Positive Regulation Of Cellular Biosynthetic Process Regulation Of Excitatory Postsynaptic Membrane Potential Cellular Response To UV-C P38MAPK Cascade Cellular Response To Vitamin B1 Regulation Of Postsynaptic Membrane Potential Cell Cycle Process Regulation Of Protein Phosphorylation Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Negative Regulation Of Signal Transduction Response To Radiation Response To Abiotic Stimulus Posttranscriptional Regulation Of Gene Expression Cellular Response To Hypoxia RNA Metabolic Process Cellular Response To Decreased Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Nucleocytoplasmic Transport Response To Peptide Biosynthetic Process	Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade JNK Cascade Signal Transduction By Phosphorylation MAPK Cascade Regulation Of Protein Kinase Activity Regulation Of MAPK Cascade Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Kinase Activity JUN Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of MAP Kinase Activity Response To Stress Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of MAPK Cascade Regulation Of Signal Transduction Response To Light Stimulus Response To External Stimulus Response To Radiation Regulation Of Signaling Intracellular Signal Transduction Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Axon Guidance Regulation Of Intracellular Signal Transduction Signal Transduction Axonogenesis Phosphorylation Cell Part Morphogenesis Axon Development Response To Stimulus Cell Morphogenesis Involved In Neuron Differentiation Response To Abiotic Stimulus Protein Phosphorylation Cellular Response To Stress Signaling
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