YY1AP1 and MAD2L2

Number of citations of the paper that reports this interaction (PubMedID 17541814)
0

Data Source:
BioGRID (affinity chromatography technology, pull down)

		YY1AP1	MAD2L2
Description		YY1 associated protein 1	mitotic arrest deficient 2 like 2
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytoplasm Ino80 Complex	Chromatin Nucleus Nucleoplasm Anaphase-promoting Complex Chromosome Cytoplasm Spindle Cytoskeleton Zeta DNA Polymerase Complex Site Of Double-strand Break
	Molecular Function	Protein Binding	Transcription Corepressor Activity Protein Binding JUN Kinase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Cell Population Proliferation Cell Differentiation Regulation Of Cell Cycle	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth Somatic Diversification Of Immunoglobulins Involved In Immune Response DNA Repair Double-strand Break Repair DNA Damage Response Actin Filament Organization Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription By Competitive Promoter Binding Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Protein Catabolic Process Error-prone Translesion Synthesis DNA Damage Response, Signal Transduction Resulting In Transcription Telomere Maintenance In Response To DNA Damage Positive Regulation Of Isotype Switching Positive Regulation Of DNA-templated Transcription Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways			Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		12 interacting genes: ATXN1 ATXN1L EWSR1 FXR1 MAD2L2 MAPK14 MAPK8IP2 MDM2 PCNT PRKAB2 VHL ZFAT	47 interacting genes: ADAM15 ADAM17 ADAM9 CAMK2B CDC20 CDH1 CIMIP1 DEPDC5 ELK1 FAM217B FTO FZR1 GSC2 IKZF1 IKZF3 INCA1 KCTD9 KRT34 MAD2L1 MAD2L1BP MBD3L1 MYBPC2 PLAGL2 POLDIP2 PPM1B PRCC PRR5L PRRC2A RAB11FIP4 RBBP6 REL REV1 REV3L SFI1 SHLD1 TCF4 THAP6 TRIM27 TRIM54 TRIM7 YPEL3 YY1AP1 ZBED1 ZMYND12 ZNF511 ZNF558 ZNF655
Entrez ID		55249	10459
HPRD ID		08485	07246
Ensembl ID		ENSG00000163374	ENSG00000116670
Uniprot IDs		B4DQQ0 I6L9C2 Q9H869	Q9UI95
PDB IDs			3ABD 3ABE 3VU7 4EXT 4GK0 4GK5 5XPT 5XPU 6BC8 6BCD 6BI7 6K07 6K08 6KEA 6KTO 6M7A 6M7B 6NIF 6VE5 6WS0 6WS5 6WW9 6WWA 7L9P
Enriched GO Terms of Interacting Partners?		POZ Domain Binding Social Behavior Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process JUN Kinase Binding Positive Regulation Of Intracellular Protein Transport Regulation Of RNA Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Protein Transport Positive Regulation Of Developmental Process Negative Regulation Of Catabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Signal Transduction Positive Regulation Of Cell Differentiation Amyloid Fibril Formation Learning Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleolus Ribonucleoprotein Complex Binding Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Response To Stress Cytoplasm Lung Alveolus Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process Positive Regulation Of Protein Transport Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Response To Formaldehyde Cellular Response To Vitamin B1 DNA Damage Response, Signal Transduction Resulting In Transcription Positive Regulation Of RNA Metabolic Process Regulation Of Intracellular Transport Regulation Of Gene Expression Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Metabolic Process Learning Or Memory Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Response To Light Stimulus Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Muscle Cell Differentiation	Mitotic Checkpoint Complex Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Metal Ion Binding Translesion Synthesis Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Protein Binding Positive Regulation Of Cell Cycle Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Regulation Of Cell Cycle DNA Binding DNA Biosynthetic Process Postreplication Repair Error-free Translesion Synthesis Positive Regulation Of Synapse Maturation DNA Synthesis Involved In DNA Repair Anaphase-promoting Complex Binding Ubiquitin-protein Transferase Activator Activity Negative Regulation Of Type I Interferon Production Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Error-prone Translesion Synthesis Regulation Of Mitotic Cell Cycle Ubiquitin Ligase Activator Activity Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle DNA-binding Transcription Factor Activity Positive Regulation Of Ubiquitin-protein Transferase Activity Zinc Ion Binding Regulation Of Mitotic Sister Chromatid Separation Regulation Of Nuclear Division Negative Regulation Of Interferon-beta Production Positive Regulation Of Catabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Process Amyloid Precursor Protein Catabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Chromosome Separation DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Regulation Of Cell Cycle Phase Transition SUMO Transferase Activity Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Mitotic Sister Chromatid Separation Anaphase-promoting Complex Regulation Of Metabolic Process Sequence-specific DNA Binding
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