VPS37C and PKNOX1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VPS37C	PKNOX1
Gene Name		vacuolar protein sorting 37 homolog C (S. cerevisiae)	PBX/knotted 1 homeobox 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	ESCRT I Complex Endosome Membrane Late Endosome Membrane Extracellular Vesicular Exosome	Nucleus Transcription Factor Complex Cytoplasm
	Molecular Function	Protein Binding Calcium-dependent Protein Binding	Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Protein Transport Viral Process Endosomal Transport Viral Life Cycle Virion Assembly Viral Protein Processing Membrane Organization Intracellular Transport Of Virus	Angiogenesis Transcription From RNA Polymerase II Promoter T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Assembly Of The HIV Virion Synthesis And Processing Of GAG, GAGPOL Polyproteins HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Membrane binding and targetting of GAG proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS			Biochemical measures ( 19260141) Cognitive performance ( 20125193) Information processing speed ( 21130836)
Protein-Protein Interactions		32 interactors: ABI2 AES APP C1orf94 CEP55 DAZAP2 DDIT3 FAM168A GOLGA2 HGS HNRNPUL1 MAPK1IP1L PDCD6 PDCD6IP PKNOX1 PLSCR1 PSMA3 RBPMS RFX6 RINT1 SH3GL1 SORBS2 SORBS3 STAM2 TACC3 TFG TFIP11 TSG101 UBC VPS28 WWP2 XIAP	15 interactors: APP HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 MEIS1 PAX6 PBX1 PBX2 POU2F1 RFX3 TLX1 VPS37C ZBTB3
Entrez ID		55048	5316
HPRD ID		15652	03653
Ensembl ID		ENSG00000167987	ENSG00000160199
Uniprot IDs		A5D8V6	E7EPN6 P55347 Q6PKH2 Q96I87
PDB IDs			1X2N
Enriched GO Terms of Interacting Partners?		Virion Assembly Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Viral Protein Processing Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of ERBB Signaling Pathway Viral Life Cycle Cellular Protein Catabolic Process Endosomal Transport Intracellular Transport Of Virus Protein Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Apoptotic Process Programmed Cell Death Regulation Of Cellular Process Cell Death Regulation Of Extracellular Vesicular Exosome Assembly Death Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Modification-dependent Protein Catabolic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Viral Process Intracellular Transport Cellular Macromolecule Catabolic Process Viral Budding Membrane Organization Gene Expression Positive Regulation Of Exocytosis Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Ubiquitination Cell Cycle Regulation Of Cellular Localization Regulation Of Transcription From RNA Polymerase II Promoter Protein Processing Negative Regulation Of Signal Transduction Establishment Of Protein Localization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Localization Positive Regulation Of Metabolic Process Proteasomal Protein Catabolic Process Cell Separation After Cytokinesis	Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Pattern Specification Process Positive Regulation Of Cellular Biosynthetic Process Anatomical Structure Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Embryonic Morphogenesis Organ Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organ Development Anterior/posterior Pattern Specification Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Embryonic Skeletal System Development Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Anatomical Structure Development Cellular Nitrogen Compound Metabolic Process Embryo Development System Development Embryonic Organ Development Developmental Process Nitrogen Compound Metabolic Process Cell Differentiation Positive Regulation Of Metabolic Process Skeletal System Development Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Skeletal System Morphogenesis Regulation Of Metabolic Process Embryonic Organ Morphogenesis Proximal/distal Pattern Formation Cell Development Chordate Embryonic Development Negative Regulation Of Neuron Differentiation Embryo Development Ending In Birth Or Egg Hatching Transcription From RNA Polymerase II Promoter Rhombomere Development
Tagcloud ?		bl bud budding cargo degrade escrt hairpin hijacks jr k38a multivesicular mvb nl4 p6 polyproteins pppy producer pseudovirus ptap retroviral retrovirus retroviruses tank tbk1 tethering tzm ubiquitylated ultrastructure vero	219a 5p aberration amongst confer consortium dys effectors enrichment epha4 epigenetic esr1 hsa ipa mcic microrna micrornas mind neuropsychological predicted psychiatric ranked respective schizophrenia searched sets strengthened thousands transcriptionally
Tagcloud (Difference) ?		bl bud budding cargo degrade escrt hairpin hijacks jr k38a multivesicular mvb nl4 p6 polyproteins pppy producer pseudovirus ptap retroviral retrovirus retroviruses tank tbk1 tethering tzm ubiquitylated ultrastructure vero	219a 5p aberration amongst confer consortium dys effectors enrichment epha4 epigenetic esr1 hsa ipa mcic microrna micrornas mind neuropsychological predicted psychiatric ranked respective schizophrenia searched sets strengthened thousands transcriptionally
Tagcloud (Intersection) ?