PKNOX1 and ZBTB3

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		PKNOX1	ZBTB3
Gene Name		PBX/knotted 1 homeobox 1	zinc finger and BTB domain containing 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Cytoplasm	Nucleus
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Protein Heterodimerization Activity	DNA Binding Metal Ion Binding
	Biological Process	Angiogenesis Transcription From RNA Polymerase II Promoter T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Cognitive performance ( 20125193) Information processing speed ( 21130836)
Protein-Protein Interactions		15 interactors: APP HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 MEIS1 PAX6 PBX1 PBX2 POU2F1 RFX3 TLX1 VPS37C ZBTB3	21 interactors: ANKRD2 BIN1 EIF5B FOXM1 GATA4 GTF2A1L IKBKG IRF6 JADE2 LEF1 NR3C1 PKNOX1 PPARG PROX1 SKIL SMAD3 SSX3 SUPT5H THRA ZMYM2 ZNF556
Entrez ID		5316	79842
HPRD ID		03653	15693
Ensembl ID		ENSG00000160199	ENSG00000185670
Uniprot IDs		E7EPN6 P55347 Q6PKH2 Q96I87	Q9H5J0
PDB IDs		1X2N
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Pattern Specification Process Positive Regulation Of Cellular Biosynthetic Process Anatomical Structure Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Embryonic Morphogenesis Organ Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organ Development Anterior/posterior Pattern Specification Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Embryonic Skeletal System Development Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Anatomical Structure Development Cellular Nitrogen Compound Metabolic Process Embryo Development System Development Embryonic Organ Development Developmental Process Nitrogen Compound Metabolic Process Cell Differentiation Positive Regulation Of Metabolic Process Skeletal System Development Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Skeletal System Morphogenesis Regulation Of Metabolic Process Embryonic Organ Morphogenesis Proximal/distal Pattern Formation Cell Development Chordate Embryonic Development Negative Regulation Of Neuron Differentiation Embryo Development Ending In Birth Or Egg Hatching Transcription From RNA Polymerase II Promoter Rhombomere Development	Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Epithelial Cell Differentiation DNA-templated Transcription, Initiation Nitrogen Compound Metabolic Process Epithelium Development Gland Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Differentiation Regulation Of Cellular Process Tissue Development Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Organ Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Steroid Hormone Mediated Signaling Pathway Lens Fiber Cell Differentiation Regulation Of Cell Differentiation Positive Regulation Of Cell Development Muscle Structure Development Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		219a 5p aberration amongst confer consortium dys effectors enrichment epha4 epigenetic esr1 hsa ipa mcic microrna micrornas mind neuropsychological predicted psychiatric ranked respective schizophrenia searched sets strengthened thousands transcriptionally
Tagcloud (Difference) ?		219a 5p aberration amongst confer consortium dys effectors enrichment epha4 epigenetic esr1 hsa ipa mcic microrna micrornas mind neuropsychological predicted psychiatric ranked respective schizophrenia searched sets strengthened thousands transcriptionally
Tagcloud (Intersection) ?