PKNOX1 and HOXB7

Number of citations of the paper that reports this interaction (PubMedID 9366523)
0

Data Source:
HPRD (in vivo)

		PKNOX1	HOXB7
Description		PBX/knotted 1 homeobox 1	homeobox B7
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytoplasm	Chromatin Nucleus Nucleoplasm Cytosol Nuclear Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Angiogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Hemopoiesis T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Embryonic Skeletal System Morphogenesis Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Blood and toenail selenium levels ( 25343990) Cognitive performance ( 20125193) Information processing speed ( 21130836)	Hypertension ( 27618447) LDL cholesterol levels ( 32203549) Mean arterial pressure ( 30487518) Pulse pressure ( 27618447 28135244) Systolic blood pressure ( 27618447 30487518)
Interacting Genes		56 interacting genes: ANKRD49 APC APP ARL13B BAIAP2 BEX4 BLOC1S5 BORCS6 BRD2 C1S CAPRIN1 CMYA5 EEF1A2 EXOC7 FAM110B FHL2 FIBP FMNL2 GAS7 HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 ITGB3BP KIF1A KIF1B MACF1 MEIS1 MPP3 NRIP1 NUP58 PAX6 PBX1 PBX2 PBX3 PFDN2 POU2F1 PRSS3 RAB11FIP4 RFX3 RNF40 SPTBN1 STAT1 STAT6 SYNM TCOF1 TEKT4P2 TET2 TLX1 TRIM59 TTC3 UBR1 VPS37C WIZ ZBTB3	13 interacting genes: APP CLK3 CREBBP CSNK2A1 EP300 GMNN HOXB6 IRAK3 NFKBIA PARP1 PBX1 PKNOX1 XRCC6
Entrez ID		5316	3217
HPRD ID		03653	00850
Ensembl ID		ENSG00000160199	ENSG00000260027
Uniprot IDs		B4DGV5 E7EPN6 P55347 Q6PKH2 Q96I87	P09629
PDB IDs		1X2N
Enriched GO Terms of Interacting Partners?		Pattern Specification Process Positive Regulation Of Transcription By RNA Polymerase II Chromatin DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Regionalization Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Embryonic Morphogenesis Regulation Of RNA Metabolic Process Microtubule Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Animal Organ Morphogenesis Eye Development Regulation Of Nucleobase-containing Compound Metabolic Process Microtubule-based Transport Nucleus Proximal/distal Pattern Formation Retrograde Neuronal Dense Core Vesicle Transport DNA Binding Axo-dendritic Transport Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Organelle Transport Along Microtubule Transport Along Microtubule Positive Regulation Of Biosynthetic Process Neuron Development Sensory Organ Development Positive Regulation Of Macromolecule Metabolic Process Regulation Of Dendritic Spine Morphogenesis Dense Core Granule Cytoskeletal Transport Transcription Coregulator Binding Anterograde Axonal Transport Regulation Of Metabolic Process Vesicle Transport Along Microtubule Positive Regulation Of Metabolic Process Cytoskeleton-dependent Intracellular Transport Regulation Of Gene Expression Transcription Corepressor Binding	Transcription Regulator Complex Regulation Of Innate Immune Response Regulation Of Gene Expression Immune System Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Protein Localization To Nucleus Damaged DNA Binding Activation Of Innate Immune Response Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Defense Response Histone H3K27 Acetyltransferase Activity Regulation Of Transcription By RNA Polymerase II Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Defense Response Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Innate Immune Response Regulation Of Immune Response Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Recombinational Repair Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Protein-DNA Complex Negative Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Cellular Response To Radiation Positive Regulation Of DNA-templated Transcription Hemopoiesis Innate Immune Response-activating Signaling Pathway DNA-binding Transcription Factor Binding Activation Of Immune Response Canonical NF-kappaB Signal Transduction Positive Regulation Of RNA Metabolic Process Response To Radiation Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Double-strand Break Repair Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
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