VPS37C

Gene Name		vacuolar protein sorting 37 homolog C (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	ESCRT I Complex Endosome Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Calcium-dependent Protein Binding
	Biological Process	Protein Transport Viral Process Endosomal Transport Viral Life Cycle Virion Assembly Viral Protein Processing Membrane Organization Intracellular Transport Of Virus
Pathways		Assembly Of The HIV Virion Synthesis And Processing Of GAG, GAGPOL Polyproteins HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Membrane binding and targetting of GAG proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-protein Interactions		32 interactors: ABI2 AES APP C1orf94 CEP55 DAZAP2 DDIT3 FAM168A GOLGA2 HGS HNRNPUL1 MAPK1IP1L PDCD6 PDCD6IP PKNOX1 PLSCR1 PSMA3 RBPMS RFX6 RINT1 SH3GL1 SORBS2 SORBS3 STAM2 TACC3 TFG TFIP11 TSG101 UBC VPS28 WWP2 XIAP
Entrez ID		55048
HPRD ID		15652
Ensembl ID		ENSG00000167987
Uniprot IDs		A5D8V6
PDB IDs
Enriched GO Terms of Interacting Partners?		Virion Assembly Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Viral Protein Processing Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of ERBB Signaling Pathway Viral Life Cycle Cellular Protein Catabolic Process Endosomal Transport Intracellular Transport Of Virus Protein Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Apoptotic Process Programmed Cell Death Regulation Of Cellular Process Cell Death Regulation Of Extracellular Vesicular Exosome Assembly Death Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Modification-dependent Protein Catabolic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Viral Process Intracellular Transport Cellular Macromolecule Catabolic Process Viral Budding Membrane Organization Gene Expression Positive Regulation Of Exocytosis Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Ubiquitination Cell Cycle Regulation Of Cellular Localization Regulation Of Transcription From RNA Polymerase II Promoter Protein Processing Negative Regulation Of Signal Transduction Establishment Of Protein Localization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Localization Positive Regulation Of Metabolic Process Proteasomal Protein Catabolic Process Cell Separation After Cytokinesis
Tagcloud ?		bl bud budding cargo degrade escrt hairpin hijacks jr k38a multivesicular mvb nl4 p6 polyproteins pppy producer pseudovirus ptap retroviral retrovirus retroviruses tank tbk1 tethering tzm ubiquitylated ultrastructure vero