PID1 and ADAMTSL4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PID1	ADAMTSL4
Gene Name		phosphotyrosine interaction domain containing 1	ADAMTS-like 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Cellular_component Interstitial Matrix Endoplasmic Reticulum Lumen
	Molecular Function		Protease Binding Metalloendopeptidase Activity Protein Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Energy Reserve Metabolic Process Positive Regulation Of Gene Expression Regulation Of Mitochondrial Fusion Cellular Response To Leptin Stimulus Fat Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Fat Cell Proliferation Mitochondrion Morphogenesis Cellular Response To Cytokine Stimulus Cellular Response To Interleukin-6 Cellular Response To Tumor Necrosis Factor Cellular Response To Fatty Acid Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Mitochondrial DNA Replication Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of ATP Biosynthetic Process Positive Regulation Of ATP Biosynthetic Process Negative Regulation Of Glucose Import In Response To Insulin Stimulus	Protein O-linked Glycosylation Proteolysis Apoptotic Process Extracellular Matrix Organization Protein O-linked Fucosylation Positive Regulation Of Apoptotic Process Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS		Pulmonary function (interaction) ( 23284291) Reasoning ( 21107309)	Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		13 interactors: ADAMTSL4 BANP CCDC33 CRX GOLGA2 GOPC KRTAP10-1 LRP1 MDFI NME1 NOTCH2NL SPERT THAP1	106 interactors: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 C19orf66 C6orf165 CATSPER1 CCDC26 CHCHD2 CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL1P1 GNE GNMT GOLGA8EP HGF HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587
Entrez ID		55022	54507
HPRD ID		07944	18237
Ensembl ID		ENSG00000153823	ENSG00000143382
Uniprot IDs		Q7Z2X4	F8WAD0 Q6UY14 Q9UFG7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasmic Sequestering Of Protein Regulation Of Binding Cytoplasmic Sequestering Of CFTR Protein Beta-amyloid Clearance Positive Regulation Of Photoreceptor Cell Differentiation Regulation Of DNA Binding Negative Regulation Of Intracellular Protein Transport Negative Regulation Of Binding Negative Regulation Of Intracellular Transport Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Regulation Of Protein Transport Developmental Process Regulation Of Establishment Of Protein Localization Negative Regulation Of Protein Transport Negative Regulation Of Golgi To Plasma Membrane Protein Transport Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization Regulation Of Golgi To Plasma Membrane Protein Transport	Multicellular Organismal Development Keratinization Organ Development Developmental Process Keratinocyte Differentiation System Development Anatomical Structure Development Epidermis Development Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Epidermal Cell Differentiation Sensory Organ Development Response To Organic Substance Organic Anion Transport Positive Regulation Of Neuron Projection Regeneration Regulation Of Transcription From RNA Polymerase II Promoter Epithelium Development Cellular Response To Thyroid Hormone Stimulus MRNA Transcription From RNA Polymerase II Promoter Skin Development Positive Regulation Of Transcription, DNA-templated Transepithelial Transport Semicircular Canal Development Positive Regulation Of Gene Expression Regulation Of Branching Involved In Salivary Gland Morphogenesis MRNA Transcription Response To Thyroid Hormone Negative Regulation Of Hydrolase Activity Cell Differentiation Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?		adaptor apla associates augmented changed confocal depending developmentally disrupted e3 est fe65 ligase localization motif nedd4 originally phosphotyrosine pid2 pplp pull putative subcellular tag ubiquitin ubiquitinated ubiquitylation w243kp245k ww	abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Difference) ?		adaptor apla associates augmented changed confocal depending developmentally disrupted e3 est fe65 ligase localization motif nedd4 originally phosphotyrosine pid2 pplp pull putative subcellular tag ubiquitin ubiquitinated ubiquitylation w243kp245k ww	abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Intersection) ?