NTF4

Description		neurotrophin 4
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Synaptic Vesicle Axon Dendrite
	Molecular Function	Signaling Receptor Binding Nerve Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Long-term Memory Sensory Organ Boundary Specification Adult Locomotory Behavior Epidermis Development Nerve Development Ameloblast Differentiation Nerve Growth Factor Signaling Pathway Mechanoreceptor Differentiation Negative Regulation Of Programmed Cell Death Negative Regulation Of Neuron Apoptotic Process Neuron Projection Morphogenesis Modulation Of Chemical Synaptic Transmission Innervation Taste Bud Development
Pathways		PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling NTF4 activates NTRK2 (TRKB) signaling Activated NTRK2 signals through RAS Activated NTRK2 signals through PLCG1 Activated NTRK2 signals through PLCG1 Activated NTRK2 signals through PI3K Activated NTRK2 signals through FRS2 and FRS3 Activated NTRK2 signals through FRS2 and FRS3
Drugs
Diseases		Primary open angle glaucoma
GWAS		Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598)
Interacting Genes		8 interacting genes: ADAMTSL4 BDNF CLIC1 CRX GLRX3 LRP1 NGFR NTRK2
Entrez ID		4909
HPRD ID		01220
Ensembl ID		ENSG00000225950
Uniprot IDs		P34130
PDB IDs		1B8M 1B98 1HCF
Enriched GO Terms of Interacting Partners?		Brain-derived Neurotrophic Factor Receptor Signaling Pathway Neurotrophin Binding Neurotrophin Signaling Pathway Nervous System Development Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Synapse Assembly Nerve Development Positive Regulation Of Transcytosis Alpha-2 Macroglobulin Receptor Activity Cellular Response To Amyloid-beta Response To Amyloid-beta Apolipoprotein Receptor Activity Brain-derived Neurotrophic Factor Receptor Activity Pigment Cell Development Positive Regulation Of Axonogenesis Retina Development In Camera-type Eye Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway System Development Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Reverse Cholesterol Transport Amyloid-beta Binding Regulation Of Transcytosis Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Dorsal Aorta Development Dendrite Positive Regulation Of Cell Junction Assembly Modulation Of Chemical Synaptic Transmission Lipoprotein Particle Receptor Binding Death Receptor Activity Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Brain-derived Neurotrophic Factor Binding Protease Binding Circadian Rhythm Regulation Of Axonogenesis Positive Regulation Of Developmental Process Astrocyte Activation Involved In Immune Response Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Neurotrophin Receptor Activity Trans-synaptic Signaling By BDNF Dendritic Spine Positive Regulation Of Neuron Projection Development Nerve Growth Factor Receptor Binding Positive Regulation Of Lysosomal Protein Catabolic Process Negative Regulation Of Hair Follicle Development Nerve Growth Factor Binding Regulation Of Synapse Assembly Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Anatomical Structure Morphogenesis Regulation Of Programmed Cell Death
Tagcloud ?