GAB1 and INSR

  • Number of citations of the paper that reports this interaction (PMID 9658397)
  • 13
  • Data Source:
  • HPRD (two hybrid, in vitro)

GAB1

INSR

Gene Name GRB2-associated binding protein 1 insulin receptor
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 31 interactors: ARHGAP32 C1QBP CRK CRKL EGFR EPOR FRS2 GAB2 GRAP2 GRB2 GTF2A1L INPP5D INSR LAT2 MAP3K3 MAPK1 MAPK3 MAPK4 MARK2 MET MST1R PDGFRB PIK3CG PIK3R1 PLCG1 PLCG2 PTPN11 PTPN18 RET SHC1 SOS1 77 interactors: ACP1 ADRB2 AHSG ARF1 ARHGAP26 CALM1 CALM2 CALM3 CAV1 CAV3 CBL CEACAM1 CRK CRKL CSK DOK1 DOK4 DOK5 ENPP1 FABP4 FRS2 GAB1 GNB2L1 GRB10 GRB14 GRB7 HRAS IGF1R IGF2 INS INSRR IRF7 IRS1 IRS2 JAK1 JAK2 KHDRBS1 KRT27 KRT31 MAD2L1 MAPK3 PIK3R1 PIK3R3 PLCG1 PRKCA PRKCD PTK2 PTPN1 PTPN11 PTPN12 PTPN2 PTPN6 PTPRC PTPRF RAF1 RASA1 SH2B1 SH2B2 SHC1 SMAD2 SNX1 SNX2 SNX4 SNX6 SOCS1 SOCS2 SOCS3 SOCS6 SORBS1 SRC STAT5A STAT5B SYNCRIP TEAD1 VAV1 VAV3 YWHAB
Entrez ID 2549 3643
HPRD ID 05116 00975
Ensembl ID ENSG00000109458 ENSG00000171105
Uniprot IDs Q13480 Q9HA84 P06213
PDB IDs 1GAG 1I44 1IR3 1IRK 1P14 1RQQ 2AUH 2B4S 2DTG 2HR7 2Z8C 3BU3 3BU5 3BU6 3EKK 3EKN 3ETA 3LOH 3W11 3W12 3W13 3W14 4IBM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adaptor  amplifies  antagonism  bdl  bile  binder  broad  ccl5  chemokine  conditional  contributor  duct  elucidate  exacerbated  fibrogenesis  fibrosis  fibrotic  gab1cko  grb2  hepatocyte  hepatocytes  injections  knockout  ligation  lipopolysaccharide  liver  livers  myofibroblasts  tetrachloride 
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
Tagcloud (Difference) ?
adaptor  amplifies  antagonism  bdl  bile  binder  broad  ccl5  chemokine  conditional  contributor  duct  elucidate  exacerbated  fibrogenesis  fibrosis  fibrotic  gab1cko  grb2  hepatocyte  hepatocytes  injections  knockout  ligation  lipopolysaccharide  liver  livers  myofibroblasts  tetrachloride 
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
Tagcloud (Intersection) ?