GAB1 and CRKL

  • Number of citations of the paper that reports this interaction (PMID 10871282)
  • 77
  • Data Source:
  • HPRD (two hybrid)

GAB1

CRKL

Gene Name GRB2-associated binding protein 1 v-crk avian sarcoma virus CT10 oncogene homolog-like
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 31 interactors: ARHGAP32 C1QBP CRK CRKL EGFR EPOR FRS2 GAB2 GRAP2 GRB2 GTF2A1L INPP5D INSR LAT2 MAP3K3 MAPK1 MAPK3 MAPK4 MARK2 MET MST1R PDGFRB PIK3CG PIK3R1 PLCG1 PLCG2 PTPN11 PTPN18 RET SHC1 SOS1 71 interactors: ABL1 AOX1 ARHGAP32 ARHGEF5 BCAR1 BCR BIK BLNK CBL CBLB CD34 CRK DAB1 DOCK2 DOK1 EPHB6 EPOR ERBB2 ERBB3 ETV6 EVL FCGR1A GAB1 GAB2 GAREM GRB2 GRN IFNAR1 IGF1R INPP5D INSR IRS4 ITGB1 KHDRBS1 KIDINS220 KIT LAMA5 LTBP4 LYN MAP4K1 MAP4K5 MEGF6 MSL1 NEDD9 NOTCH2 PDGFRA PHC2 PIK3R1 PIK3R2 PLEKHA1 PLSCR1 POLR1D PPFIBP2 PTPN11 PXN RAPGEF1 RPL31 SHANK3 SHC1 SOS1 SOS2 STAT5A STAT5B SYK TGFB1I1 TNS2 TYK2 WAC WAS WIPF1 YY1
Entrez ID 2549 1399
HPRD ID 05116 03596
Ensembl ID ENSG00000109458 ENSG00000099942
Uniprot IDs Q13480 Q9HA84 P46109
PDB IDs 2BZX 2BZY 2DBK 2EO3 2LQN 2LQW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adaptor  amplifies  antagonism  bdl  bile  binder  broad  ccl5  chemokine  conditional  contributor  duct  elucidate  exacerbated  fibrogenesis  fibrosis  fibrotic  gab1cko  grb2  hepatocyte  hepatocytes  injections  knockout  ligation  lipopolysaccharide  liver  livers  myofibroblasts  tetrachloride 
actions  adaptor  antiapoptotic  behavior  believed  chemotactic  converting  crkii  focused  grb2  igfs  implicated  intracellularly  ir  irs  mediates  metabolism  mitogenic  nucleus  occur  organogenesis  outlines  promoting  shc  signalling  signals  stimulating  substrate  transmitting 
Tagcloud (Difference) ?
amplifies  antagonism  bdl  bile  binder  broad  ccl5  chemokine  conditional  contributor  duct  elucidate  exacerbated  fibrogenesis  fibrosis  fibrotic  gab1cko  hepatocyte  hepatocytes  injections  knockout  ligation  lipopolysaccharide  liver  livers  myofibroblasts  tetrachloride 
actions  antiapoptotic  behavior  believed  chemotactic  converting  crkii  focused  igfs  implicated  intracellularly  ir  irs  mediates  metabolism  mitogenic  nucleus  occur  organogenesis  outlines  promoting  shc  signalling  signals  stimulating  substrate  transmitting 
Tagcloud (Intersection) ?
adaptor  grb2