GAB1 and PTPN11

  • Number of citations of the paper that reports this interaction (PMID 10871282)
  • 77
  • Data Source:
  • HPRD (two hybrid)

GAB1

PTPN11

Gene Name GRB2-associated binding protein 1 protein tyrosine phosphatase, non-receptor type 11
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 31 interactors: ARHGAP32 C1QBP CRK CRKL EGFR EPOR FRS2 GAB2 GRAP2 GRB2 GTF2A1L INPP5D INSR LAT2 MAP3K3 MAPK1 MAPK3 MAPK4 MARK2 MET MST1R PDGFRB PIK3CG PIK3R1 PLCG1 PLCG2 PTPN11 PTPN18 RET SHC1 SOS1 114 interactors: ACTN4 ARHGAP1 AXL BCR BDKRB2 BTLA C6orf25 CAT CAV1 CBL CCKBR CD33 CDH5 CEACAM1 CHUK CRKL CSF2RB CSF3R CTLA4 CXCR4 DAB1 DDR1 EGFR EPHA2 EPOR ERBB2 FCRL3 FLT1 FLT4 FRS2 FRS3 FYN GAB1 GAB2 GAB3 GHR GRB2 GRIN2B HNRNPU IFNAR1 IFNGR1 IGF1R IL4R IL6ST INPP5D INSR IRS1 IRS2 IRS4 JAK1 JAK2 KDR KIR2DL5A KIT KLRC1 LAIR1 LCK LEPR LIFR LILRB4 MAP3K4 MAP3K5 MAPK3 MET MPL MPZL1 MS4A2 MVP NEDD9 NTRK1 NTRK2 PAG1 PDGFRA PDGFRB PECAM1 PIK3CG PIK3R1 PILRA PILRB PLCG1 PRKCA PRKCB PRKCH PRLR PTK2 PTK2B PTPN6 PXN RET ROS1 RPIA SELE SHC1 SIGLEC11 SIGLEC12 SIGLEC7 SIRPA SIT1 SLAMF1 SLAMF6 SOCS3 SOS1 SPRY2 SRC STAT1 STAT3 STAT5A STAT5B SYNCRIP TEK TIE1 TNFRSF1A TREML1 TRIM32
Entrez ID 2549 5781
HPRD ID 05116 01470
Ensembl ID ENSG00000109458 ENSG00000179295
Uniprot IDs Q13480 Q9HA84 Q06124
PDB IDs 2SHP 3B7O 3MOW 3O5X 3TKZ 3TL0 4DGP 4DGX 4GWF 4H1O 4H34 4JE4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adaptor  amplifies  antagonism  bdl  bile  binder  broad  ccl5  chemokine  conditional  contributor  duct  elucidate  exacerbated  fibrogenesis  fibrosis  fibrotic  gab1cko  grb2  hepatocyte  hepatocytes  injections  knockout  ligation  lipopolysaccharide  liver  livers  myofibroblasts  tetrachloride 
absolute  case  cases  count  died  eleven  female  indispensable  interval  jmml  juvenile  male  median  monocytes  mutation  myelomonocytic  observation  obviously  onset  peripheral  platelet  plt  progressive  ras  retrospectively  slow  sure  wbc  white 
Tagcloud (Difference) ?
adaptor  amplifies  antagonism  bdl  bile  binder  broad  ccl5  chemokine  conditional  contributor  duct  elucidate  exacerbated  fibrogenesis  fibrosis  fibrotic  gab1cko  grb2  hepatocyte  hepatocytes  injections  knockout  ligation  lipopolysaccharide  liver  livers  myofibroblasts  tetrachloride 
absolute  case  cases  count  died  eleven  female  indispensable  interval  jmml  juvenile  male  median  monocytes  mutation  myelomonocytic  observation  obviously  onset  peripheral  platelet  plt  progressive  ras  retrospectively  slow  sure  wbc  white 
Tagcloud (Intersection) ?