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ZBTB3 and BIN1
Number of citations of the paper that reports this interaction (PMID
20211142
)
148
Data Source:
BioGRID
(two hybrid)
ZBTB3
BIN1
Gene Name
zinc finger and BTB domain containing 3
bridging integrator 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleus
Cytoplasm
Synaptic Vesicle
Actin Cytoskeleton
Membrane
Z Disc
T-tubule
Axon
I Band
Node Of Ranvier
Axon Initial Segment
Varicosity
Axon Terminus
Cerebellar Mossy Fiber
Lipid Tube
Molecular Function
DNA Binding
Metal Ion Binding
Protein Binding
Protein Complex Binding
Identical Protein Binding
Protein Heterodimerization Activity
Tau Protein Binding
GTPase Binding
RNA Polymerase Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Endocytosis
Cell Proliferation
Viral Process
Muscle Cell Differentiation
Positive Regulation Of Apoptotic Process
Positive Regulation Of GTPase Activity
Regulation Of Neuron Differentiation
Positive Regulation Of Endocytosis
Positive Regulation Of Astrocyte Differentiation
Lipid Tube Assembly
Regulation Of Cell Cycle Arrest
Pathways
Drugs
Diseases
GWAS
Alzheimer's disease (
22832961
21460840
21627779
22005930
)
Alzheimer's disease (late onset) (
21460841
21390209
)
Protein-Protein Interactions
21 interactors:
ANKRD2
BIN1
EIF5B
FOXM1
GATA4
GTF2A1L
IKBKG
IRF6
JADE2
LEF1
NR3C1
PKNOX1
PPARG
PROX1
SKIL
SMAD3
SSX3
SUPT5H
THRA
ZMYM2
ZNF556
36 interactors:
ABL1
AMPH
AP2A1
AP2A2
APP
ASAP2
ATXN2
CUX1
DLGAP4
DNM1
DNM2
FBP1
ITGA1
ITGA3
ITGA6
MAP4K3
MBNL1
MYC
PLD1
PLD2
PTK2
RAP1A
RFX3
RIN2
RIN3
SH3GL2
SH3GLB1
SNX4
SOS1
SOS2
SYN1
SYNJ1
TP73
UBC
XRCC4
ZBTB3
Entrez ID
79842
274
HPRD ID
15693
03150
Ensembl ID
ENSG00000185670
ENSG00000136717
Uniprot IDs
Q9H5J0
B7Z6Y2
O00499
Q9BTH3
PDB IDs
1MUZ
1MV0
1MV3
2FIC
2RMY
2RND
Enriched GO Terms of Interacting Partners
?
Transcription, DNA-templated
RNA Biosynthetic Process
Gene Expression
Transcription From RNA Polymerase II Promoter
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Nitrogen Compound Metabolic Process
Epithelial Cell Differentiation
DNA-templated Transcription, Initiation
Nitrogen Compound Metabolic Process
Epithelium Development
Gland Development
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Cell Differentiation
Regulation Of Cellular Process
Tissue Development
Positive Regulation Of Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Organ Development
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Steroid Hormone Mediated Signaling Pathway
Lens Fiber Cell Differentiation
Regulation Of Cell Differentiation
Positive Regulation Of Cell Development
Muscle Structure Development
Negative Regulation Of Cellular Metabolic Process
Regulation Of Signaling
Endocytosis
Generation Of Neurons
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Projection Organization
Regulation Of ERBB Signaling Pathway
Neurogenesis
Neuron Projection Morphogenesis
Cell Projection Morphogenesis
Cell Part Morphogenesis
Regulation Of Signal Transduction
Axon Guidance
Neuron Differentiation
Neuron Development
Nervous System Development
Vesicle-mediated Transport
Chemotaxis
Signaling
Neuron Projection Development
Locomotion
Cell Communication
Anatomical Structure Morphogenesis
Cell Morphogenesis
Axonogenesis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Axon Development
Negative Regulation Of Signaling
Cell Differentiation
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Morphogenesis Involved In Neuron Differentiation
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Cellular Process
Cell Development
Positive Regulation Of Catalytic Activity
Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neurotrophin Signaling Pathway
System Development
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Metabolic Process
Cell Morphogenesis Involved In Differentiation
Regulation Of Catalytic Activity
Regulation Of Intracellular Signal Transduction
Movement Of Cell Or Subcellular Component
Cellular Response To Growth Factor Stimulus
Regulation Of Body Fluid Levels
Positive Regulation Of Apoptotic Process
Blood Coagulation
Tagcloud
?
a2m
algorithm
allele
alzheimer
amplicons
apoe
apoj
biochip
clut
combinations
cr1
determina
e3
e4
epsilon2
epsilon4
exoc3l2
gab2
genotyping
immobilized
microchip
oligonucleotides
picalm
predis
rs11136000
sporadic
studying
tion
tomm40
Tagcloud (Difference)
?
a2m
algorithm
allele
alzheimer
amplicons
apoe
apoj
biochip
clut
combinations
cr1
determina
e3
e4
epsilon2
epsilon4
exoc3l2
gab2
genotyping
immobilized
microchip
oligonucleotides
picalm
predis
rs11136000
sporadic
studying
tion
tomm40
Tagcloud (Intersection)
?