ZBTB3 and EIF5B

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ZBTB3	EIF5B
Gene Name		zinc finger and BTB domain containing 3	eukaryotic translation initiation factor 5B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytosol
	Molecular Function	DNA Binding Metal Ion Binding	Translation Initiation Factor Activity GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Cellular Protein Metabolic Process
Pathways			Translation GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Cap-dependent Translation Initiation
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		21 interactors: ANKRD2 BIN1 EIF5B FOXM1 GATA4 GTF2A1L IKBKG IRF6 JADE2 LEF1 NR3C1 PKNOX1 PPARG PROX1 SKIL SMAD3 SSX3 SUPT5H THRA ZMYM2 ZNF556	9 interactors: BRCA1 CBL CSNK2A1 ECT2 EIF1AX ETS1 PAXIP1 TFCP2 ZBTB3
Entrez ID		79842	9669
HPRD ID		15693	07304
Ensembl ID		ENSG00000185670	ENSG00000158417
Uniprot IDs		Q9H5J0	O60841 Q8N5A0
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Epithelial Cell Differentiation DNA-templated Transcription, Initiation Nitrogen Compound Metabolic Process Epithelium Development Gland Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Differentiation Regulation Of Cellular Process Tissue Development Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Organ Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Steroid Hormone Mediated Signaling Pathway Lens Fiber Cell Differentiation Regulation Of Cell Differentiation Positive Regulation Of Cell Development Muscle Structure Development Negative Regulation Of Cellular Metabolic Process	Positive Regulation Of Histone H3-K4 Methylation Response To Ionizing Radiation Positive Regulation Of Histone Acetylation Regulation Of Cellular Component Organization Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Regulation Of Chromosome Organization Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Histone Methylation Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Histone Acetylation Regulation Of Histone Methylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Response To Hydrogen Peroxide Regulation Of Organelle Organization Regulation Of Cell Cycle Positive Regulation Of Histone Modification Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of Histone H4-K16 Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Nitrogen Compound Metabolic Process Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Response To Abiotic Stimulus Response To Radiation Negative Regulation Of Cell Cycle Gene Expression Signal Transduction In Response To DNA Damage Regulation Of Metabolic Process Cellular Response To Reactive Oxygen Species Regulation Of Cell Cycle Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Histone H3-K9 Acetylation Transcription, DNA-templated Signal Transduction By P53 Class Mediator RNA Biosynthetic Process Regulation Of Histone Modification Positive Regulation Of Angiogenesis Response To Hydrogen Peroxide Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation
Tagcloud ?			40s 60s 80s accordingly configuration cryo distinguished em facilitated facilitates gmppnp gtpase hcv initiator ires joining met peptidyl reconstructions redefines reorientation ribosomal ribosome rotational substates trna trnai universally
Tagcloud (Difference) ?			40s 60s 80s accordingly configuration cryo distinguished em facilitated facilitates gmppnp gtpase hcv initiator ires joining met peptidyl reconstructions redefines reorientation ribosomal ribosome rotational substates trna trnai universally
Tagcloud (Intersection) ?