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PFKM and DYNLL1
Number of citations of the paper that reports this interaction (PubMedID
14760703
)
0
Data Source:
HPRD
(in vitro)
PFKM
DYNLL1
Description
phosphofructokinase, muscle
dynein light chain LC8-type 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
6-phosphofructokinase Complex
Membrane
Apical Plasma Membrane
Sperm Principal Piece
Kinetochore
Nucleus
Chromosome
Cytoplasm
Mitochondrion
Centrosome
Cytosol
Cytoskeleton
Cytoplasmic Dynein Complex
Microtubule
Microtubule Associated Complex
Plasma Membrane
Cilium
COP9 Signalosome
Microtubule Cytoskeleton
Membrane
Secretory Granule
Dynein Complex
Site Of Double-strand Break
Tertiary Granule Membrane
Mitotic Spindle
Ciliary Tip
Ficolin-1-rich Granule Membrane
Axon Cytoplasm
Molecular Function
Nucleotide Binding
Catalytic Activity
6-phosphofructokinase Activity
Protein Binding
ATP Binding
Phosphofructokinase Activity
Kinase Activity
Transferase Activity
Kinase Binding
Identical Protein Binding
Metal Ion Binding
Fructose Binding
Fructose-6-phosphate Binding
Enzyme Inhibitor Activity
Protein Binding
Enzyme Binding
Nitric-oxide Synthase Regulator Activity
Nitric-oxide Synthase Inhibitor Activity
Identical Protein Binding
Protein-containing Complex Binding
Dynein Intermediate Chain Binding
Deoxyribonuclease Inhibitor Activity
Scaffold Protein Binding
Biological Process
Glycogen Catabolic Process
Fructose 6-phosphate Metabolic Process
Glycolytic Process
Fructose 1,6-bisphosphate Metabolic Process
Positive Regulation Of Insulin Secretion
Glucose Homeostasis
Positive Regulation Of Transcription By RNA Polymerase II
Muscle Cell Cellular Homeostasis
Carbohydrate Phosphorylation
Glycolytic Process Through Fructose-6-phosphate
Canonical Glycolysis
Glycolysis From Storage Polysaccharide Through Glucose-1-phosphate
Apoptotic Process
DNA Damage Response
Microtubule-based Process
Spermatid Development
Substantia Nigra Development
Positive Regulation Of Intracellular Transport
Intraciliary Retrograde Transport
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Negative Regulation Of Phosphorylation
Motile Cilium Assembly
Negative Regulation Of Nitric Oxide Biosynthetic Process
DNA Strand Resection Involved In Replication Fork Processing
Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing
Pathways
Glycolysis
Activation of BIM and translocation to mitochondria
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Macroautophagy
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
Intraflagellar transport
RHO GTPases Activate Formins
Neutrophil degranulation
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
AURKA Activation by TPX2
HCMV Early Events
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS
Glycated hemoglobin levels (
34059833
)
Hematocrit (
27863252
32888494
)
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
High light scatter reticulocyte count (
32888494
)
Immature fraction of reticulocytes (
32888494
)
Longevity (90 years and older) (
25199915
)
Mean corpuscular hemoglobin concentration (
32888494
)
Mean corpuscular volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Metabolite levels (
23823483
)
Pulse pressure (
30578418
)
Red blood cell count (
32888494
)
High light scatter reticulocyte count (
27863252
32888494
)
High light scatter reticulocyte percentage of red cells (
27863252
32888494
)
Immature fraction of reticulocytes (
27863252
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Reading disability or specific language impairment (pleiotropy) (
25065397
)
Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) (
25065397
)
Reticulocyte count (
27863252
32888494
)
Reticulocyte fraction of red cells (
27863252
32888494
)
Interacting Genes
20 interacting genes:
ATP6V0A4
CAV3
CEBPA
DLC1
DYNLL1
FHL2
HGS
LSM7
MAPK3
NDUFB2
NOS1
PCNA
PDGFRL
PFKL
SFRP2
SFRP4
SIAH1
SUMO2
TEAD4
UBTD1
108 interacting genes:
ACTB
ACTC1
ACTG1
ALDOA
AMOTL2
B3GALT4
BACH1
BCAS1
BCL2L11
BMF
C14orf119
C19orf44
CA2
CACNB1
CCDC28A
CIMAP1A
CLIP2
COXFA4L2
CS
DAZ1
DCTN5
DLG4
DLGAP1
DNAJB9
DNM2
DNM3
DNMT1
DPPA3
DYNC1H1
DYNC1I1
DYRK1A
EEF1A1
ERG28
FAM153A
FAM53B
GABARAPL1
GABARAPL2
GAPDH
GLUD1
GLUL
GNL3L
GPHN
GPRIN2
GRIN3A
HIP1R
HMBOX1
HOMER3
HSPA8
IHO1
INPP1
IQUB
KANK2
LDHA
MAP1B
MARK3
MAST2
ME2
MORC3
MORN3
MRE11
MTA1
MTR
MYO10
MYO5A
NDEL1
NFKBIA
NOS1
NRF1
NTRK1
NTRK2
NTRK3
OR7C2
OTUD6A
PAK1
PAN2
PARD3
PAX6
PCM1
PFKM
PFKP
PKIA
PKIB
PKIG
POLH
PPP3R2
RAB4A
RACK1
RASGRP4
REDIC1
RGS2
SHROOM3
SLC13A1
SMCP
TERT
THAP10
THAP8
TNFRSF14
TP53BP1
TRIM54
TSNARE1
TUBA3C
TUBB
TXNDC17
VIM
ZHX1
ZMYND11
ZNF354A
ZNF710
Entrez ID
5213
8655
HPRD ID
01988
03334
Ensembl ID
ENSG00000152556
ENSG00000088986
Uniprot IDs
A0A024R0Y5
A0A0S2Z4I1
A0A2R8Y891
F8VTQ3
P08237
P63167
Q6FGH9
PDB IDs
4OMT
1CMI
3ZKE
3ZKF
6GZJ
6GZL
6RLB
6SC2
7D35
8PR0
8PR1
8PTK
8RGG
Enriched GO Terms of Interacting Partners
?
Caveola
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Anatomical Structure Formation Involved In Morphogenesis
Heart Trabecula Formation
Negative Regulation Of Signaling
Negative Regulation Of Transport
Negative Regulation Of Cell Communication
Negative Regulation Of Potassium Ion Transport
Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Z Disc
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Cell Development
Myoblast Fusion
Regulation Of Cell Communication
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Signaling
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Hematopoietic Stem Cell Proliferation
Response To Hormone
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Apoptotic Process
Canonical Wnt Signaling Pathway
Wnt-protein Binding
Ubiquitin-like Protein Ligase Binding
Protein-containing Complex Binding
Cellular Developmental Process
Sodium Channel Regulator Activity
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Membrane Repolarization
T-tubule
Cardiac Muscle Cell Development
Regulation Of Sodium Ion Transmembrane Transport
Regulation Of Nerve Growth Factor Receptor Activity
Regulation Of Proteolysis
Syncytium Formation By Plasma Membrane Fusion
Negative Regulation Of Signal Transduction
Negative Regulation Of Sarcomere Organization
Cell-cell Fusion
Regulation Of Signal Transduction By Receptor Internalization
Cardiac Cell Development
Syncytium Formation
Negative Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential
Negative Regulation Of Cell Population Proliferation
Regulation Of Protein Catabolic Process
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Regulation Of Transcription By RNA Polymerase II
Response To Dexamethasone
Positive Regulation Of Macromolecule Biosynthetic Process
PCNA Complex
Cytoskeleton
Microtubule
Cytoplasm
Postsynaptic Density
Microtubule Binding
Neurotrophin Receptor Activity
Neurotrophin Binding
Cytosol
Pyruvate Metabolic Process
Neuron Projection Morphogenesis
Nucleotide Binding
Cell Projection Morphogenesis
Glycolytic Process
Fructose 1,6-bisphosphate Metabolic Process
Cytoskeleton Organization
Actin Filament
Identical Protein Binding
ADP Catabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Microtubule-based Process
Apical Junction Complex
ADP Metabolic Process
Nucleoside Diphosphate Catabolic Process
Ribonucleoside Diphosphate Catabolic Process
Positive Regulation Of Cellular Component Biogenesis
Replication Fork
CAMP-dependent Protein Kinase Inhibitor Activity
Cytoskeleton-dependent Intracellular Transport
Dendritic Spine
Organelle Organization
Axon
Establishment Of Organelle Localization
Axonogenesis
Microtubule Associated Complex
Carbohydrate Catabolic Process
Peptidyl-cysteine S-nitrosylase Activity
6-phosphofructokinase Activity
6-phosphofructokinase Complex
Beta-tubulin Binding
Ribonucleoside Diphosphate Metabolic Process
Purine Ribonucleotide Catabolic Process
Microtubule Cytoskeleton Organization
Substantia Nigra Development
Negative Regulation Of Protein Import Into Nucleus
Myelination In Peripheral Nervous System
Regulation Of Transport
Nucleoside Diphosphate Metabolic Process
Regulation Of Transepithelial Transport
Calyx Of Held
Fructose-6-phosphate Binding
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Tagcloud (Difference)
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Tagcloud (Intersection)
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