PFKM and UBTD1

Number of citations of the paper that reports this interaction (PMID 24211586)
0

Data Source:
BioGRID (two hybrid)

		PFKM	UBTD1
Gene Name		phosphofructokinase, muscle	ubiquitin domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol 6-phosphofructokinase Complex Apical Plasma Membrane Extracellular Vesicular Exosome Sperm Principal Piece
	Molecular Function	6-phosphofructokinase Activity Protein Binding ATP Binding Protein C-terminus Binding Kinase Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Fructose Binding
	Biological Process	Carbohydrate Metabolic Process Fructose 6-phosphate Metabolic Process Glucose Metabolic Process Glycolytic Process Pathogenesis Positive Regulation Of Insulin Secretion Glucose Homeostasis Small Molecule Metabolic Process Muscle Cell Cellular Homeostasis Carbohydrate Phosphorylation Protein Oligomerization
Pathways		Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		13 interactors: ATP6V0A4 CAV3 DYNLL1 FHL2 HGS LSM7 MAPK3 NDUFB2 NOS1 PCNA PFKL SIAH1 UBTD1	13 interactors: BCOR CD1A FZD5 KIAA2026 MID1 MID2 MRFAP1L1 PFKM RANBP2 RNF10 TEAD1 TRIM39 UBE2D4
Entrez ID		5213	80019
HPRD ID		01988	08568
Ensembl ID		ENSG00000152556	ENSG00000165886
Uniprot IDs		P08237	Q9HAC8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Localization Heart Trabecula Formation Positive Regulation Of Organelle Organization Positive Regulation Of Histone Acetylation Myoblast Fusion Negative Regulation Of Potassium Ion Transport Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Heart Trabecula Morphogenesis Syncytium Formation Regulation Of Sodium Ion Transmembrane Transport Striated Muscle Cell Differentiation Negative Regulation Of Calcium Ion Transport Phagosome Maturation Regulation Of Histone Acetylation Regulation Of Signaling Trabecula Morphogenesis Positive Regulation Of Transport Myotube Differentiation Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transport Muscle Cell Differentiation Regulation Of Sodium Ion Transport Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Deoxyribonuclease Activity Negative Regulation Of Apolipoprotein Binding Regulation Of Signal Transduction By Receptor Internalization Negative Regulation Of Sarcomere Organization Regulation Of Nerve Growth Factor Receptor Activity Cardiac Muscle Cell Development Anatomical Structure Morphogenesis Positive Regulation Of Histone Modification Cellular Metabolic Process Regulation Of Cardiac Muscle Contraction Response To Stimulus Response To Organic Substance Regulation Of Vesicle-mediated Transport Cellular Nitrogen Compound Metabolic Process Regulation Of Organelle Organization Regulation Of Striated Muscle Contraction Negative Regulation Of Transport Leading Strand Elongation Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of Ion Transport Regulation Of Intracellular Transport Regulation Of Signal Transduction Interaction With Host Cardiac Muscle Cell Differentiation Response To Heat	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Localization To Microtubule Protein Localization To Cytoskeleton Negative Regulation Of Histone H3-K36 Methylation Negative Regulation Of Tooth Mineralization Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Pattern Specification Process Axis Specification Depurination Regulation Of Chorionic Trophoblast Cell Proliferation Spemann Organizer Formation Protein Localization To Organelle Cellular Protein Modification Process Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Negative Regulation Of Schwann Cell Proliferation Positive Regulation Of Signal Transduction Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Specification Of Axis Polarity Negative Regulation Of Odontogenesis Negative Regulation Of Glucokinase Activity Positive Regulation Of Stem Cell Maintenance DNA Dealkylation Involved In DNA Repair Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Histone H3-K4 Methylation Base-excision Repair, AP Site Formation Chorionic Trophoblast Cell Differentiation Protein K6-linked Ubiquitination Glucose Homeostasis Chorion Development Pathogenesis Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Myelination Regulation Of Tight Junction Assembly Negative Regulation Of Glial Cell Proliferation Post-embryonic Camera-type Eye Development Fructose 6-phosphate Metabolic Process Branching Involved In Labyrinthine Layer Morphogenesis Positive Regulation Of Intracellular Signal Transduction Histone H2A Monoubiquitination Regulation Of Metabolic Process Lateral Mesoderm Development Cardiovascular System Development Negative Regulation Of Viral Release From Host Cell Histone H2A Ubiquitination
Tagcloud ?			attenuation barrier besides britain constitutes copyright correlates creates damageing depend depends feedback great impacts ireland john ltd mdm2 mutually passageing premature senescence serial society sons transformed tumourigenesis wiley worse
Tagcloud (Difference) ?			attenuation barrier besides britain constitutes copyright correlates creates damageing depend depends feedback great impacts ireland john ltd mdm2 mutually passageing premature senescence serial society sons transformed tumourigenesis wiley worse
Tagcloud (Intersection) ?