PFKM

Gene Name		phosphofructokinase, muscle
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol 6-phosphofructokinase Complex Apical Plasma Membrane Extracellular Vesicular Exosome Sperm Principal Piece
	Molecular Function	6-phosphofructokinase Activity Protein Binding ATP Binding Protein C-terminus Binding Kinase Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Fructose Binding
	Biological Process	Carbohydrate Metabolic Process Fructose 6-phosphate Metabolic Process Glucose Metabolic Process Glycolytic Process Pathogenesis Positive Regulation Of Insulin Secretion Glucose Homeostasis Small Molecule Metabolic Process Muscle Cell Cellular Homeostasis Carbohydrate Phosphorylation Protein Oligomerization
Pathways		Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-protein Interactions		13 interactors: ATP6V0A4 CAV3 DYNLL1 FHL2 HGS LSM7 MAPK3 NDUFB2 NOS1 PCNA PFKL SIAH1 UBTD1
Entrez ID		5213
HPRD ID		01988
Ensembl ID		ENSG00000152556
Uniprot IDs		P08237
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Localization Heart Trabecula Formation Positive Regulation Of Organelle Organization Positive Regulation Of Histone Acetylation Myoblast Fusion Negative Regulation Of Potassium Ion Transport Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Heart Trabecula Morphogenesis Syncytium Formation Regulation Of Sodium Ion Transmembrane Transport Striated Muscle Cell Differentiation Negative Regulation Of Calcium Ion Transport Phagosome Maturation Regulation Of Histone Acetylation Regulation Of Signaling Trabecula Morphogenesis Positive Regulation Of Transport Myotube Differentiation Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transport Muscle Cell Differentiation Regulation Of Sodium Ion Transport Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Deoxyribonuclease Activity Negative Regulation Of Apolipoprotein Binding Regulation Of Signal Transduction By Receptor Internalization Negative Regulation Of Sarcomere Organization Regulation Of Nerve Growth Factor Receptor Activity Cardiac Muscle Cell Development Anatomical Structure Morphogenesis Positive Regulation Of Histone Modification Cellular Metabolic Process Regulation Of Cardiac Muscle Contraction Response To Stimulus Response To Organic Substance Regulation Of Vesicle-mediated Transport Cellular Nitrogen Compound Metabolic Process Regulation Of Organelle Organization Regulation Of Striated Muscle Contraction Negative Regulation Of Transport Leading Strand Elongation Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of Ion Transport Regulation Of Intracellular Transport Regulation Of Signal Transduction Interaction With Host Cardiac Muscle Cell Differentiation Response To Heat
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