PFKM and LSM7

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PFKM	LSM7
Gene Name		phosphofructokinase, muscle	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol 6-phosphofructokinase Complex Apical Plasma Membrane Extracellular Vesicular Exosome Sperm Principal Piece	Spliceosomal Complex Cytosol
	Molecular Function	6-phosphofructokinase Activity Protein Binding ATP Binding Protein C-terminus Binding Kinase Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Fructose Binding	Protein Binding U6 SnRNA Binding
	Biological Process	Carbohydrate Metabolic Process Fructose 6-phosphate Metabolic Process Glucose Metabolic Process Glycolytic Process Pathogenesis Positive Regulation Of Insulin Secretion Glucose Homeostasis Small Molecule Metabolic Process Muscle Cell Cellular Homeostasis Carbohydrate Phosphorylation Protein Oligomerization	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Processing RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways		Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates	mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ATP6V0A4 CAV3 DYNLL1 FHL2 HGS LSM7 MAPK3 NDUFB2 NOS1 PCNA PFKL SIAH1 UBTD1	23 interactors: DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SART3 SMN1 SNRPD3 SNRPF TACC1 ZSCAN26
Entrez ID		5213	51690
HPRD ID		01988	06287
Ensembl ID		ENSG00000152556	ENSG00000130332
Uniprot IDs		P08237	Q9UK45
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Localization Heart Trabecula Formation Positive Regulation Of Organelle Organization Positive Regulation Of Histone Acetylation Myoblast Fusion Negative Regulation Of Potassium Ion Transport Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Heart Trabecula Morphogenesis Syncytium Formation Regulation Of Sodium Ion Transmembrane Transport Striated Muscle Cell Differentiation Negative Regulation Of Calcium Ion Transport Phagosome Maturation Regulation Of Histone Acetylation Regulation Of Signaling Trabecula Morphogenesis Positive Regulation Of Transport Myotube Differentiation Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transport Muscle Cell Differentiation Regulation Of Sodium Ion Transport Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Deoxyribonuclease Activity Negative Regulation Of Apolipoprotein Binding Regulation Of Signal Transduction By Receptor Internalization Negative Regulation Of Sarcomere Organization Regulation Of Nerve Growth Factor Receptor Activity Cardiac Muscle Cell Development Anatomical Structure Morphogenesis Positive Regulation Of Histone Modification Cellular Metabolic Process Regulation Of Cardiac Muscle Contraction Response To Stimulus Response To Organic Substance Regulation Of Vesicle-mediated Transport Cellular Nitrogen Compound Metabolic Process Regulation Of Organelle Organization Regulation Of Striated Muscle Contraction Negative Regulation Of Transport Leading Strand Elongation Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of Ion Transport Regulation Of Intracellular Transport Regulation Of Signal Transduction Interaction With Host Cardiac Muscle Cell Differentiation Response To Heat	Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Metabolic Process RNA Splicing MRNA Processing RNA Splicing, Via Transesterification Reactions Nuclear-transcribed MRNA Catabolic Process RNA Processing MRNA Catabolic Process RNA Catabolic Process MRNA Splicing, Via Spliceosome Aromatic Compound Catabolic Process RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Gene Expression Spliceosomal SnRNP Assembly Cellular Macromolecule Catabolic Process Histone MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process NcRNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Catabolic Process RRNA Processing RRNA Metabolic Process Termination Of RNA Polymerase II Transcription Ribosome Biogenesis Histone H3-K4 Acetylation Positive Regulation Of Histone Deubiquitination Notochord Cell Development Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Positive Regulation Of Hemoglobin Biosynthetic Process Cellular Metabolic Process DNA-templated Transcription, Termination Metabolic Process MRNA 3'-end Processing Cellular Macromolecular Complex Assembly Axial Mesoderm Formation Retrograde Transport, Plasma Membrane To Golgi RNA 3'-end Processing Regulation Of Hemoglobin Biosynthetic Process Notochord Formation Regulation Of Protein Deubiquitination Lens Fiber Cell Morphogenesis Axial Mesoderm Morphogenesis Regulation Of Protein Localization
Tagcloud ?			angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm5 lsm57 lsm6 lsm657 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal
Tagcloud (Difference) ?			angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm5 lsm57 lsm6 lsm657 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal
Tagcloud (Intersection) ?