WBP11 and WBP4

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		WBP11	WBP4
Gene Name		WW domain binding protein 11	WW domain binding protein 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Nucleoplasm Spliceosomal Complex Plasma Membrane Nuclear Speck
	Molecular Function	Single-stranded DNA Binding Protein Binding Protein Phosphatase Type 1 Regulator Activity Poly(A) RNA Binding WW Domain Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding
	Biological Process	RRNA Processing MRNA Processing RNA Splicing Regulation Of Catalytic Activity	MRNA Cis Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 23266558)
Protein-Protein Interactions		28 interactors: APBB1 ARF1 C5orf22 CD2BP2 CTNNBL1 DDX17 DDX5 FYN GIGYF2 GRB2 ITSN1 MCRS1 NCK2 PIK3R1 PPP1CA PPP1CB PPP1CC PQBP1 PRPF40A RBM5 RTN4IP1 RUNX1T1 SRC TESC TRAF4 TRIP10 VIM WBP4	44 interactors: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207
Entrez ID		51729	11193
HPRD ID		18293	16086
Ensembl ID		ENSG00000084463	ENSG00000120688
Uniprot IDs		F5H721 Q9Y2W2	B7Z4M2 O75554
PDB IDs			2DK1 2JXW
Enriched GO Terms of Interacting Partners?		Enzyme Linked Receptor Protein Signaling Pathway RNA Splicing Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus RNA Processing MRNA Splicing, Via Spliceosome Response To Growth Factor RNA Splicing, Via Transesterification Reactions MRNA Processing Positive Regulation Of Signal Transduction Apoptotic Process Programmed Cell Death Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Signaling Cell Death Death Entrainment Of Circadian Clock By Photoperiod MRNA Metabolic Process T Cell Costimulation Triglyceride Catabolic Process Regulation Of Gene Expression Regulation Of Intracellular Estrogen Receptor Signaling Pathway Photoperiodism Entrainment Of Circadian Clock Regulation Of Signal Transduction Regulation Of Cellular Process Acylglycerol Catabolic Process Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Axon Guidance Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Adhesion Ephrin Receptor Signaling Pathway Neurotrophin Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organismal Development Positive Regulation Of Cell-cell Adhesion Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway System Development Response To Radiation Developmental Process Anatomical Structure Development Response To Abiotic Stimulus Regulation Of Apoptotic Process Regulation Of T Cell Activation Positive Regulation Of Cell Activation Neuron Differentiation	MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Cellular Component Assembly MRNA Splice Site Selection Cellular Process Metabolic Process MRNA 3'-end Processing Transcription, DNA-templated RNA Biosynthetic Process RNA 3'-end Processing Spliceosomal SnRNP Assembly Posttranscriptional Regulation Of Gene Expression Attachment Of Spindle Microtubules To Kinetochore Rhythmic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Translational Initiation Macromolecule Biosynthetic Process Positive Regulation Of Translation Actin Polymerization Or Depolymerization Negative Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Circadian Rhythm Regulation Of RNA Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Positive Regulation Of Gene Expression MRNA Polyadenylation Cellular Response To Osmotic Stress
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