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DDX47 and MLH1
Number of citations of the paper that reports this interaction (PMID
20706999
)
2
Data Source:
BioGRID
(two hybrid)
DDX47
MLH1
Gene Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
mutL homolog 1
Image
Gene Ontology Annotations
Cellular Component
Nucleolus
Membrane
Synaptonemal Complex
Male Germ Cell Nucleus
Nucleus
Nucleoplasm
Chiasma
Membrane
MutLalpha Complex
Molecular Function
Helicase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
ATPase Activity
Guanine/thymine Mispair Binding
MutSalpha Complex Binding
Biological Process
RRNA Processing
MRNA Processing
RNA Splicing
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Nuclear-transcribed MRNA Poly(A) Tail Shortening
Resolution Of Meiotic Recombination Intermediates
DNA Repair
Mismatch Repair
Double-strand Break Repair Via Nonhomologous End Joining
Male Meiosis Chromosome Segregation
Synapsis
Spermatogenesis
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Somatic Hypermutation Of Immunoglobulin Genes
Meiotic Metaphase I Plate Congression
Isotype Switching
Negative Regulation Of Mitotic Recombination
Oogenesis
Meiotic Spindle Midzone Assembly
Pathways
Meiotic recombination
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch Repair
Drugs
Diseases
GWAS
Protein-Protein Interactions
5 interactors:
APP
KRAS
MLH1
PRNP
SRPK1
74 interactors:
ABCC3
ABHD16A
ACER3
ACTG2
AGR2
AIFM1
ALDOA
ANXA6
AP2B1
APRT
ARAF
ASS1
ATF2
BLM
BRCA1
CAB39L
CAPN5
CASP3
CKAP4
CKB
CXorf57
DDX47
EEF1G
EEF2
EIF2A
ELP6
EXO1
EXOC3
FBXO32
FCGBP
FLNB
FRMD6
GABARAP
GSTP1
IGKC
KPNA2
LGALS4
MAP2K6
MBD4
MLH3
MSH3
MSH4
MUC2
MYC
MYL6
MYOG
NDRG1
NT5C3B
ORC4
PARP12
PARVA
PCNA
PMS1
PMS2
PSMA1
PTGDS
PTPRH
RAD23B
RAD9A
RAPGEFL1
SEC61A1
SELENBP1
SERPINF1
SPERT
SQSTM1
STAP2
TRIM23
TRIM29
TXN
TXN2
UBOX5
VAMP8
ZC3H11A
ZER1
Entrez ID
51202
4292
HPRD ID
10863
00390
Ensembl ID
ENSG00000213782
ENSG00000076242
Uniprot IDs
Q9H0S4
P40692
Q59EG3
PDB IDs
3BER
3NA3
3RBN
Enriched GO Terms of Interacting Partners
?
Cell Development
Cellular Copper Ion Homeostasis
Copper Ion Homeostasis
Learning Or Memory
Cognition
Axon Guidance
Immune Response
MRNA Processing
Cell Differentiation
Visual Learning
Single-organism Behavior
Response To Stress
Visual Behavior
Axonogenesis
MRNA 3'-end Processing
MRNA Metabolic Process
Associative Learning
Axon Development
RNA Processing
Cell Morphogenesis Involved In Neuron Differentiation
Behavior
Chemotaxis
RNA 3'-end Processing
Neuron Projection Morphogenesis
Meiotic Spindle Midzone Assembly
Meiotic Metaphase I Plate Congression
Cell Morphogenesis Involved In Differentiation
Immune System Process
Learning
Sexual Reproduction
Innate Immune Response
Transition Metal Ion Homeostasis
Neuron Projection Development
Anatomical Structure Development
Negative Regulation Of Mitotic Recombination
Synaptic Growth At Neuromuscular Junction
Regulation Of Nitrogen Compound Metabolic Process
Cell Projection Morphogenesis
Cell Part Morphogenesis
Collateral Sprouting In Absence Of Injury
Neuron Development
Developmental Process
Reproduction
Regulation Of Mitotic Recombination
Male Meiosis Chromosome Segregation
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Cell Morphogenesis
Regulation Of Protein Phosphorylation
Chromosome Segregation
Collateral Sprouting
Cellular Response To Stress
Cellular Response To DNA Damage Stimulus
Cellular Response To Stimulus
Response To Stimulus
Mismatch Repair
Response To Stress
DNA Metabolic Process
DNA Catabolic Process
DNA Recombination
Negative Regulation Of Cell Cycle
DNA Repair
Cell Cycle
Cell Cycle Process
Cellular Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Response To Organic Substance
DNA Damage Checkpoint
Mitotic DNA Damage Checkpoint
Mucus Secretion
Regulation Of Cell Cycle
Mitotic DNA Integrity Checkpoint
Nitrogen Compound Metabolic Process
Cellular Response To Organic Substance
Apoptotic Process
Programmed Cell Death
Nucleic Acid Phosphodiester Bond Hydrolysis
Cell Death
Death
Response To Abiotic Stimulus
Cell Cycle Checkpoint
Apoptotic Signaling Pathway
Nucleobase-containing Compound Metabolic Process
Cellular Response To Dexamethasone Stimulus
Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Response To Dexamethasone
Homeostatic Process
Mitotic Cell Cycle Checkpoint
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
DNA Catabolic Process, Exonucleolytic
Somatic Recombination Of Immunoglobulin Gene Segments
G2 DNA Damage Checkpoint
DNA Catabolic Process, Endonucleolytic
Regulation Of Apoptotic DNA Fragmentation
Somatic Diversification Of Immunoglobulins
Reciprocal Meiotic Recombination
Anatomical Structure Development
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Actin-mediated Cell Contraction
Tagcloud
?
9p24
actionable
arid1a
atlas
barr
bystander
cd274
cdkn2a
classifier
comes
comprises
cpg
ebv
enrollment
epstein
fail
gastrogenus
genomically
harbor
innocent
instability
intimately
l2
lytic
microsatellite
msi
noncoding
pdcd1lg2
qualify
Tagcloud (Difference)
?
9p24
actionable
arid1a
atlas
barr
bystander
cd274
cdkn2a
classifier
comes
comprises
cpg
ebv
enrollment
epstein
fail
gastrogenus
genomically
harbor
innocent
instability
intimately
l2
lytic
microsatellite
msi
noncoding
pdcd1lg2
qualify
Tagcloud (Intersection)
?