CEP55 and ANXA11

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid, two hybrid, two hybrid)

		CEP55	ANXA11
Name		centrosomal protein 55	annexin A11
Structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytoskeleton Membrane Midbody Cleavage Furrow Intercellular Bridge Flemming Body	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Spindle Cytosol Cytoskeleton Plasma Membrane Vesicle Membrane Membrane Midbody Extracellular Matrix Melanosome Specific Granule Azurophil Granule Phagocytic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Phosphatidylserine Binding RNA Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylethanolamine Binding MHC Class II Protein Complex Binding S100 Protein Binding Calcium-dependent Protein Binding
	Biological Process	Mitotic Cytokinesis Nucleus Organization Mitotic Metaphase Chromosome Alignment Establishment Of Protein Localization Cell Division Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Midbody Abscission Cranial Skeletal System Development	Phagocytosis Cytokinetic Process Cell Division Response To Calcium Ion
GWAS		High density lipoprotein cholesterol levels ( 30498476 ) Metabolite levels ( 23823483 )	Chronic obstructive pulmonary disease-related biomarkers ( 23144326 ) Diabetic kidney disease ( 26305897 ) Sarcoidosis ( 22936702 32826979 ) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848 )
Novel Interactors		None recorded	1 novel interactors: MPHOSPH9
Interacting Genes		94 interacting genes: AIRIM AKAP9 ANXA11 ARHGEF15 BAG4 C1orf216 CBY2 CCBE1 CCDC120 CCHCR1 CDC37 CDC45 CDK1 CDSN CEP57L1 CFTR COL8A1 CPSF7 DTNB ECSIT EIF1AD ENKD1 ESS2 EXOSC5 FAM161B FAM90A1 FBF1 FXR2 GOLGA2 GOLGA8DP HAUS1 HGS HNRNPA0 HSF2BP KANK2 KIFC3 KRT31 LENG1 LGALS4 LRRC23 MAPK1 MAPK1IP1L MFAP1 MIA3 MORF4L2 NDEL1 NEDD4L NOS3 NTAQ1 NXF1 OGT PCNT PDCD6IP PEF1 PIN1 PLEKHG6 PLK1 POLM POM121 PPP1R16B PRPF6 PSEN2 PSMC2 PTPN23 PWWP3A RAB3D RBM14 RBM17 RBM22 RBM42 RBPMS RCOR3 RNF32 SDCBP SF1 SFPQ SNRPB SNRPN SNW1 SS18L1 SUPT5H TCL1A TEAD4 TEX11 TFG TFIP11 TP53BP2 TSG101 UBC VPS37C VPS37D WASHC1 WASHC3 ZNF48	19 interacting genes: ALG2 ARSA CDC42 CEP55 ENO2 EWSR1 FUBP1 HNRNPH3 KRTAP13-2 KRTAP6-2 NFKBID OGT PDCD6 PLSCR1 S100A6 SRI TFG WWOX ZDHHC17
Entrez ID		55165	311
HPRD ID		12569	03983
Ensembl ID		ENSG00000138180	ENSG00000122359
Uniprot IDs		Q53EZ4	P50995 Q5T0G8
PDB IDs		3E1R 3WUT 3WUU 3WUV	9FOF 9FOR
GO Terms Enriched among Interactors		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Protein Binding Spliceosomal Complex Centrosome MRNA Processing Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway RNA Splicing Nucleoplasm MRNA Metabolic Process Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Catalytic Step 2 Spliceosome Cytoskeleton Multivesicular Body Assembly Multivesicular Body Organization Positive Regulation Of Exosomal Secretion Late Endosome To Vacuole Transport Organelle Organization Regulation Of Exosomal Secretion Regulation Of Extracellular Exosome Assembly Endosome Transport Via Multivesicular Body Sorting Pathway RNA Processing Calcium-dependent Protein Binding RNA Binding Viral Budding Via Host ESCRT Complex Multivesicular Body Sorting Pathway Positive Regulation Of Exocytosis Viral Budding MRNA Binding Protein Localization To Vacuole Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cellular Component Assembly Nucleic Acid Metabolic Process Microtubule Nucleation Cytosol Establishment Of Protein Localization To Vacuole ESCRT I Complex Centriole Cytoplasm Spindle Nucleic Acid Binding U4/U6 X U5 Tri-snRNP Complex Microtubule Cytoskeleton Organization Involved In Mitosis MRNA Cis Splicing, Via Spliceosome SnRNP Binding Endosome Organization Microtubule Organizing Center Organization Membrane Fission Microtubule-based Process Organelle Assembly	Identical Protein Binding