CEP55 and SNW1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP55	SNW1
Gene Name		centrosomal protein 55kDa	SNW domain containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Centriole Membrane Midbody Cleavage Furrow Intercellular Bridge	Chromatin Nucleus Nucleoplasm Spliceosomal Complex Positive Transcription Elongation Factor Complex B Nuclear Matrix Catalytic Step 2 Spliceosome SMAD3-SMAD4 Protein Complex
	Molecular Function	Protein Binding	Transcription Coactivator Activity Transcription Corepressor Activity Notch Binding Protein Binding Nuclear Hormone Receptor Binding Vitamin D Receptor Binding Retinoic Acid Receptor Binding Poly(A) RNA Binding SMAD Binding
	Biological Process	Mitotic Cytokinesis Cell Separation After Cytokinesis Nucleus Organization Mitotic Metaphase Plate Congression Establishment Of Protein Localization	Negative Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Gene Expression Viral Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation By Host Of Viral Transcription Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of MRNA Splicing, Via Spliceosome Retinoic Acid Receptor Signaling Pathway Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Neurogenesis Positive Regulation Of Histone H3-K4 Methylation Regulation Of Vitamin D Receptor Signaling Pathway Positive Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Retinoic Acid
Pathways			Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Notch-HLH transcription pathway Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant NOTCH1 Intracellular Domain Regulates Transcription Generic Transcription Pathway Pre-NOTCH Transcription and Translation Signaling by NOTCH1 Pre-NOTCH Expression and Processing Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Constitutive Signaling by NOTCH1 PEST Domain Mutants FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS			Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573)
Protein-Protein Interactions		55 interactors: AKAP9 ANXA11 ARHGEF15 C1orf109 CCBE1 CCDC53 CCHCR1 CDC45 CDK1 CDSN CEP57L1 DTNB ECSIT EIF1AD FAM90A1 FBF1 FXR2 GOLGA8DP HAUS1 HGS KIFC3 MAPK1 MAPK1IP1L MFAP1 MIA3 MORF4L2 MUM1 NOS3 PCNT PDCD6IP PEF1 PIN1 PLEKHG6 PLK1 POLM POM121 PPP1R16B PSEN2 PTPN23 RAB3D RBM17 RBM22 RCOR3 RNF32 SDCBP SNRPB SNW1 SSX2IP TCL1A TEAD4 TEX14 TFG TSG101 VPS37C VPS37D	58 interactors: ACTN2 ASCC2 CEP55 CIR1 CXorf56 DAXX EP300 GOLGA2 HDAC2 IKBKG IKZF1 JDP2 KRT40 LRP2BP LZTS2 MAGEA1 MAPK6 MEN1 MFAP1 MSL1 MTUS2 NCOR1 NCOR2 NHP2L1 NOTCH1 NOTCH3 NR0B1 NR0B2 PABPN1 PCBD2 PGR PPIL1 PRKAA2 RARA RB1 RBL1 RBL2 RBPJ RINT1 RXRA SART1 SIN3A SIRT1 SKI SMAD2 SMAD3 SMAD4 SRC TEX11 TFIP11 TNNT1 TOP1 TRAF1 TRIM15 TTC14 VAV2 VDR ZSCAN1
Entrez ID		55165	22938
HPRD ID		12569	04340
Ensembl ID		ENSG00000138180	ENSG00000100603
Uniprot IDs		Q53EZ4	G3V3A4 Q13573
PDB IDs		3E1R
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Localization Establishment Of Protein Localization Virion Assembly Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Exocytosis Protein Transport Viral Protein Processing Positive Regulation Of Transport Mitotic Cell Cycle Process Regulation Of Vesicle-mediated Transport Cell Cycle Regulation Of Exocytosis Mitotic Cell Cycle Organelle Organization Cell Division Microtubule Cytoskeleton Organization Positive Regulation Of Extracellular Vesicular Exosome Assembly Intracellular Transport Of Virus Cell Cycle Process Regulation Of Cellular Localization Viral Life Cycle Centrosome Organization Membrane Organization Cellular Localization Mitotic Nuclear Envelope Disassembly Positive Regulation Of Metabolic Process Microtubule Organizing Center Organization Regulation Of Protein Metabolic Process Regulation Of Organelle Organization Anatomical Structure Development Nuclear Envelope Disassembly G2/M Transition Of Mitotic Cell Cycle Viral Process Microtubule-based Process Viral Budding Developmental Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Anatomical Structure Morphogenesis Cell Differentiation Regulation Of Signal Transduction Cellular Response To DNA Damage Stimulus Cell Projection Morphogenesis Regulation Of Early Endosome To Late Endosome Transport Cellular Protein Localization Cell Part Morphogenesis Regulation Of Cellular Component Organization Nuclear Envelope Organization	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Gene Expression RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Organic Substance Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Organization Chromatin Modification Organ Development Regulation Of Signal Transduction Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Signaling Regulation Of Binding Response To Transforming Growth Factor Beta Positive Regulation Of Metabolic Process Cell Cycle Chromosome Organization Negative Regulation Of Cell Differentiation
Tagcloud ?		atad2 birc5 cdkn2a cldn6 crypt ct26 epcam flt1 g12d gp70 hif1a homozygously immunome immunotherapies mabs mhc mki67 ms4a8a ms4a8b muc2 mutated nras pbk syngeneic synonymous top2a transcriptome trp53 undifferentiated	buffer complicates consist demonstration deprotection ends exploit feasibility foci knock nucleoprotein pot1 pseudogene rap1 repetitive scaling shelterin shortening skiip telomere telomeres telomeric tif tin2 tpp1 trf1 trf2 ttaggg visualized
Tagcloud (Difference) ?		atad2 birc5 cdkn2a cldn6 crypt ct26 epcam flt1 g12d gp70 hif1a homozygously immunome immunotherapies mabs mhc mki67 ms4a8a ms4a8b muc2 mutated nras pbk syngeneic synonymous top2a transcriptome trp53 undifferentiated	buffer complicates consist demonstration deprotection ends exploit feasibility foci knock nucleoprotein pot1 pseudogene rap1 repetitive scaling shelterin shortening skiip telomere telomeres telomeric tif tin2 tpp1 trf1 trf2 ttaggg visualized
Tagcloud (Intersection) ?