Gene Name |
geminin, DNA replication inhibitor |
aurora kinase A |
Image |
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Gene Ontology Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Phosphonothreonine
- Adenosine-5\'-Diphosphate
- 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE
- 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4\',3\':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1H)-one
- 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea
- 1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea
- 1-(5-{2-[(1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl)phenyl]urea
- N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE
- N-butyl-3-{[6-(9H-purin-6-ylamino)hexanoyl]amino}benzamide
- 2-(1H-pyrazol-3-yl)-1H-benzimidazole
- N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE
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Diseases |
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GWAS |
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Protein-Protein Interactions |
26 interactors:
ARNT
AURKA
CASP3
CCDC146
CDKN1A
CDKN2A
CDT1
CSNK2A1
HDAC1
HOXA10
HOXA11
HOXA7
HOXB7
HOXC8
HOXC9
HOXD10
IMPDH1
KAT7
MCM6
NCF1
PHC1
REPIN1
SCMH1
SIX3
SMARCA4
ZNF439
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54 interactors:
APP
ARPC1B
ARPC2
AURKAIP1
BIRC5
BORA
BRCA1
CBX3
CDC20
CDC25B
CHFR
CKAP5
CSN2
GADD45A
GMNN
GSK3B
HDAC2
HDAC6
HIST3H3
IKBKB
INCENP
KIF11
KIF2C
MAPRE2
MAPRE3
MBD3
MDM2
NDC80
NFKBIA
NIN
NME1
NUF2
PLK3
PML
PPP1CA
PPP1CB
PPP1CC
PRKACA
PTTG1
PUM2
RASSF1
SRPK1
SRPK2
SUMO1
TACC1
TACC3
TLK1
TLK2
TP53
TP73
TPX2
UBE2N
USP2
VHL
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Entrez ID |
51053 |
6790 |
HPRD ID |
06783 |
04066 |
Ensembl ID |
ENSG00000112312
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ENSG00000087586
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Uniprot IDs |
O75496
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O14965
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PDB IDs |
1T6F
1UII
2LP0
2WVR
4BRY
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1MQ4
1MUO
1OL5
1OL6
1OL7
2BMC
2C6D
2C6E
2DWB
2J4Z
2J50
2NP8
2W1C
2W1D
2W1E
2W1F
2W1G
2WQE
2WTV
2WTW
2X6D
2X6E
2X81
2XNE
2XNG
2XRU
3COH
3E5A
3EFW
3FDN
3H0Y
3H0Z
3H10
3HA6
3K5U
3LAU
3M11
3MYG
3NRM
3O50
3O51
3P9J
3QBN
3R21
3R22
3UNZ
3UO4
3UO5
3UO6
3UOD
3UOH
3UOJ
3UOK
3UOL
3UP2
3UP7
3VAP
4B0G
4DEA
4DEB
4DED
4DEE
4DHF
4JAI
4JAJ
4JBO
4JBP
4JBQ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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adenosine
ags
alisertib
als
ampk
antiapoptotic
aurora
autophagy
bioavailable
cip1
cytochrome
dependently
exerts
inducing
killing
kip1
mitochondria
monophosphate
n78
nci
orally
phosphatidylinositol
proapoptotic
proautophagic
responds
sb202191
threonine
waf1
wortmannin
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Tagcloud (Difference) ? |
|
adenosine
ags
alisertib
als
ampk
antiapoptotic
aurora
autophagy
bioavailable
cip1
cytochrome
dependently
exerts
inducing
killing
kip1
mitochondria
monophosphate
n78
nci
orally
phosphatidylinositol
proapoptotic
proautophagic
responds
sb202191
threonine
waf1
wortmannin
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Tagcloud (Intersection) ? |
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