GMNN and HOXB7

Number of citations of the paper that reports this interaction (PMID 14973489)
53

Data Source:
HPRD (in vitro)

		GMNN	HOXB7
Gene Name		geminin, DNA replication inhibitor	homeobox B7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding Histone Deacetylase Binding Repressing Transcription Factor Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Mitotic Cell Cycle Protein Complex Assembly Negative Regulation Of DNA Replication Organ Morphogenesis Negative Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Anterior/posterior Pattern Specification Myeloid Cell Differentiation Embryonic Skeletal System Morphogenesis Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Pathways		DNA Replication Pre-Initiation M/G1 Transition Regulation of DNA replication Removal of licensing factors from origins CDT1 association with the CDC6:ORC:origin complex Association of licensing factors with the pre-replicative complex Cell Cycle, Mitotic Assembly of the pre-replicative complex
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: ARNT AURKA CASP3 CCDC146 CDKN1A CDKN2A CDT1 CSNK2A1 HDAC1 HOXA10 HOXA11 HOXA7 HOXB7 HOXC8 HOXC9 HOXD10 IMPDH1 KAT7 MCM6 NCF1 PHC1 REPIN1 SCMH1 SIX3 SMARCA4 ZNF439	13 interactors: APP CLK3 CREBBP CSNK2A1 EP300 GMNN HOXB6 IRAK3 NFKBIA PARP1 PBX1 PKNOX1 XRCC6
Entrez ID		51053	3217
HPRD ID		06783	00850
Ensembl ID		ENSG00000112312	ENSG00000260027
Uniprot IDs		O75496	P09629
PDB IDs		1T6F 1UII 2LP0 2WVR 4BRY
Enriched GO Terms of Interacting Partners?		Anterior/posterior Pattern Specification Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Macromolecule Biosynthetic Process Pattern Specification Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Embryonic Morphogenesis Anatomical Structure Morphogenesis Gene Expression Embryonic Organ Development Embryonic Organ Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Embryo Development Proximal/distal Pattern Formation Embryonic Skeletal System Morphogenesis Regulation Of Cell Cycle Multicellular Organismal Development Negative Regulation Of Cell Cycle Developmental Process Skeletal System Morphogenesis Organ Morphogenesis Regulation Of Cell Cycle Process Embryonic Limb Morphogenesis Embryonic Skeletal System Development Regulation Of Metabolic Process Limb Morphogenesis Skeletal System Development Metabolic Process Chromatin Modification Limb Development Organ Development System Development Anatomical Structure Development Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cell Cycle Phase Transition Positive Regulation Of Transcription, DNA-templated	Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Immune System Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Type I Interferon Production Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Type I Interferon Production Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process N-terminal Peptidyl-lysine Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Metabolic Process Regulation Of Cytokine Production RNA Biosynthetic Process Regulation Of Binding Anatomical Structure Morphogenesis Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Cellular Metabolic Process Multicellular Organismal Development N-terminal Protein Amino Acid Acetylation Anatomical Structure Development Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cytokine Production Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Homeostatic Process Organ Development Innate Immune Response Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Notch Signaling Pathway System Development Developmental Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Cell Cycle N-terminal Protein Amino Acid Modification Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Heat Regulation Of Cellular Process Response To Temperature Stimulus Viral Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process
Tagcloud ?			acquisition autonomous beta2 depleted dramatically emt knockdown luciferase m2 macrophage mb mda mesenchymal metastasis mmtv neu overexpressing pharmacologic phenotypes promoted promotes relevance reversed smad3 tam tams tgf transgenic
Tagcloud (Difference) ?			acquisition autonomous beta2 depleted dramatically emt knockdown luciferase m2 macrophage mb mda mesenchymal metastasis mmtv neu overexpressing pharmacologic phenotypes promoted promotes relevance reversed smad3 tam tams tgf transgenic
Tagcloud (Intersection) ?