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GMNN
Gene Name
geminin, DNA replication inhibitor
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Transcription Corepressor Activity
Protein Binding
Histone Deacetylase Binding
Repressing Transcription Factor Binding
Biological Process
Mitotic Cell Cycle
Protein Complex Assembly
Negative Regulation Of DNA Replication
Organ Morphogenesis
Negative Regulation Of Cell Cycle
Negative Regulation Of Transcription, DNA-templated
Pathways
DNA Replication Pre-Initiation
M/G1 Transition
Regulation of DNA replication
Removal of licensing factors from origins
CDT1 association with the CDC6:ORC:origin complex
Association of licensing factors with the pre-replicative complex
Cell Cycle, Mitotic
Assembly of the pre-replicative complex
Drugs
Diseases
GWAS
Protein-protein Interactions
26 interactors:
ARNT
AURKA
CASP3
CCDC146
CDKN1A
CDKN2A
CDT1
CSNK2A1
HDAC1
HOXA10
HOXA11
HOXA7
HOXB7
HOXC8
HOXC9
HOXD10
IMPDH1
KAT7
MCM6
NCF1
PHC1
REPIN1
SCMH1
SIX3
SMARCA4
ZNF439
Entrez ID
51053
HPRD ID
06783
Ensembl ID
ENSG00000112312
Uniprot IDs
O75496
PDB IDs
1T6F
1UII
2LP0
2WVR
4BRY
Enriched GO Terms of Interacting Partners
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Anterior/posterior Pattern Specification
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Pattern Specification Process
Macromolecule Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
RNA Metabolic Process
Embryonic Morphogenesis
Anatomical Structure Morphogenesis
Gene Expression
Embryonic Organ Development
Embryonic Organ Morphogenesis
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Embryo Development
Proximal/distal Pattern Formation
Embryonic Skeletal System Morphogenesis
Regulation Of Cell Cycle
Multicellular Organismal Development
Negative Regulation Of Cell Cycle
Developmental Process
Skeletal System Morphogenesis
Organ Morphogenesis
Regulation Of Cell Cycle Process
Embryonic Limb Morphogenesis
Embryonic Skeletal System Development
Regulation Of Metabolic Process
Limb Morphogenesis
Skeletal System Development
Metabolic Process
Chromatin Modification
Limb Development
Organ Development
System Development
Anatomical Structure Development
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Transcription, DNA-templated
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