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GMNN
Description
geminin DNA replication inhibitor
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Transcription Repressor Complex
Molecular Function
Chromatin Binding
Transcription Corepressor Activity
Protein Binding
Histone Deacetylase Binding
DNA-binding Transcription Factor Binding
Biological Process
Regulation Of DNA Replication
Regulation Of Mitotic Cell Cycle
Negative Regulation Of DNA Replication
Animal Organ Morphogenesis
Regulation Of DNA-templated DNA Replication Initiation
Positive Regulation Of Chromatin Binding
Negative Regulation Of Cell Cycle
Negative Regulation Of DNA-templated Transcription
Protein-containing Complex Assembly
DNA Replication Preinitiation Complex Assembly
Negative Regulation Of DNA-templated DNA Replication
Pathways
Assembly of the pre-replicative complex
Activation of the pre-replicative complex
Switching of origins to a post-replicative state
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Novel Interacting Genes
1 novel interacting genes:
SHANK2
Interacting Genes
34 interacting genes:
ARNT
AURKA
CASP3
CDC20
CDKN1A
CDKN2A
CDT1
CEBPA
CSNK2A1
FZR1
GLIS2
HOXA10
HOXA11
HOXA7
HOXB7
HOXC8
HOXC9
HOXD10
IMPDH1
KANK2
KAT7
LNX1
MCM6
NCF1
PHC1
PTPN11
REPIN1
RNF2
SAPCD2
SCMH1
SIX3
SMARCA4
ZNF250
ZNF439
Entrez ID
51053
HPRD ID
06783
Ensembl ID
ENSG00000112312
Uniprot IDs
O75496
PDB IDs
1T6F
1UII
2LP0
2WVR
4BRY
7KLZ
Enriched GO Terms of Interacting Partners
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Negative Regulation Of Cell Cycle
Nucleoplasm
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Regulation Of Cell Cycle
DNA Binding
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Cell Cycle Phase Transition
Anterior/posterior Pattern Specification
Nucleus
Regulation Of Transcription By RNA Polymerase II
Pattern Specification Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Sequence-specific Double-stranded DNA Binding
Regulation Of Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Regionalization
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Skeletal System Morphogenesis
Regulation Of Cell Cycle Process
Proximal/distal Pattern Formation
Regulation Of Cell Population Proliferation
Positive Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Cell Cycle Phase Transition
Embryonic Skeletal System Morphogenesis
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Cell Cycle Process
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Metabolic Process
Embryonic Morphogenesis
Negative Regulation Of Macromolecule Biosynthetic Process
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Biosynthetic Process
Chromatin Binding
Regulation Of DNA-templated DNA Replication Initiation
Regulation Of Mitotic Cell Cycle Phase Transition
Chromatin
Embryonic Organ Morphogenesis
Regulation Of Mitotic Cell Cycle
Nuclear Body
Negative Regulation Of Metabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Developmental Process
Cellular Developmental Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
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