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GMNN and PHC1
Number of citations of the paper that reports this interaction (PMID
14973489
)
53
Data Source:
HPRD
(in vitro)
GMNN
PHC1
Gene Name
geminin, DNA replication inhibitor
polyhomeotic homolog 1 (Drosophila)
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Sex Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
Molecular Function
Transcription Corepressor Activity
Protein Binding
Histone Deacetylase Binding
Repressing Transcription Factor Binding
DNA Binding
Chromatin Binding
Zinc Ion Binding
Biological Process
Mitotic Cell Cycle
Protein Complex Assembly
Negative Regulation Of DNA Replication
Organ Morphogenesis
Negative Regulation Of Cell Cycle
Negative Regulation Of Transcription, DNA-templated
Multicellular Organismal Development
Histone Ubiquitination
Cellular Response To Retinoic Acid
Pathways
DNA Replication Pre-Initiation
M/G1 Transition
Regulation of DNA replication
Removal of licensing factors from origins
CDT1 association with the CDC6:ORC:origin complex
Association of licensing factors with the pre-replicative complex
Cell Cycle, Mitotic
Assembly of the pre-replicative complex
Oxidative Stress Induced Senescence
Cellular Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions
26 interactors:
ARNT
AURKA
CASP3
CCDC146
CDKN1A
CDKN2A
CDT1
CSNK2A1
HDAC1
HOXA10
HOXA11
HOXA7
HOXB7
HOXC8
HOXC9
HOXD10
IMPDH1
KAT7
MCM6
NCF1
PHC1
REPIN1
SCMH1
SIX3
SMARCA4
ZNF439
18 interactors:
BMI1
GMNN
HSPA8
PCGF2
PHC2
PIAS2
PPP1CA
PPP1CC
RING1
RNF2
SCMH1
SFMBT1
SIAH1
SP100
SUMO1
SUMO1P1
UBE2I
ZCCHC7
Entrez ID
51053
1911
HPRD ID
06783
16009
Ensembl ID
ENSG00000112312
ENSG00000111752
Uniprot IDs
O75496
B4DF21
J3KQH6
P78364
Q6GMQ3
Q6N083
PDB IDs
1T6F
1UII
2LP0
2WVR
4BRY
2L8E
Enriched GO Terms of Interacting Partners
?
Anterior/posterior Pattern Specification
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Pattern Specification Process
Macromolecule Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
RNA Metabolic Process
Embryonic Morphogenesis
Anatomical Structure Morphogenesis
Gene Expression
Embryonic Organ Development
Embryonic Organ Morphogenesis
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Embryo Development
Proximal/distal Pattern Formation
Embryonic Skeletal System Morphogenesis
Regulation Of Cell Cycle
Multicellular Organismal Development
Negative Regulation Of Cell Cycle
Developmental Process
Skeletal System Morphogenesis
Organ Morphogenesis
Regulation Of Cell Cycle Process
Embryonic Limb Morphogenesis
Embryonic Skeletal System Development
Regulation Of Metabolic Process
Limb Morphogenesis
Skeletal System Development
Metabolic Process
Chromatin Modification
Limb Development
Organ Development
System Development
Anatomical Structure Development
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Gene Expression
Protein Modification By Small Protein Conjugation
Negative Regulation Of Cellular Metabolic Process
Chromatin Modification
Chromatin Organization
Regulation Of Metabolic Process
Anterior/posterior Pattern Specification
Peptidyl-lysine Modification
Protein Sumoylation
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Protein Ubiquitination
Histone Ubiquitination
Regulation Of RNA Metabolic Process
Chromosome Organization
Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Anatomical Structure Morphogenesis
Cellular Protein Modification Process
Pattern Specification Process
Cellular Protein Metabolic Process
Developmental Process
Regulation Of Signal Transduction
Histone H2A Monoubiquitination
Histone H2A Ubiquitination
Regulation Of Signaling
Organelle Organization
RNA Metabolic Process
Histone Monoubiquitination
Triglyceride Catabolic Process
Entrainment Of Circadian Clock By Photoperiod
Histone Modification
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Gene Expression
Protein Metabolic Process
Photoperiodism
Entrainment Of Circadian Clock
Acylglycerol Catabolic Process
Cell Division
Cell Cycle
Cellular Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Macromolecule Biosynthetic Process
Tagcloud
?
bmi1a
bmi1b
cbx2
cbx4
cbx6a
cbx6b
cbx7a
cbx7b
cbx8a
cbx8b
combs
enormous
orthologs
pcgf1
pcgf5a
pcgf5b
pcgf6
phc2a
phc2b
phc3
polyhomeotic
prc1
psc
ring1
rnf2
sce
syntenies
syntheses
trimethylates
Tagcloud (Difference)
?
bmi1a
bmi1b
cbx2
cbx4
cbx6a
cbx6b
cbx7a
cbx7b
cbx8a
cbx8b
combs
enormous
orthologs
pcgf1
pcgf5a
pcgf5b
pcgf6
phc2a
phc2b
phc3
polyhomeotic
prc1
psc
ring1
rnf2
sce
syntenies
syntheses
trimethylates
Tagcloud (Intersection)
?